Výzkumné oddělení
Vedoucí oddělení
Martin Horák
Vyberte rok
Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes
Specific pathogenic mutations in the M3 domain of the GluN1 subunit regulate the surface delivery and pharmacological sensitivity of NMDA receptors.
7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo.
The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors.