Actions

Action 1. (text from the Action Plan)
Title: Support of mobility, particularly, for PhD students employed at the IBP – a career improvement. A new institutional regulation will be established. 
GAP Principles: 18, 23, 24, 25, 26, 29
Timing: Preparation of the regulation in 2021-2022. The call for the Internal support of mobility will be announced in december for the next year and evaluated by the end of January the next year. 
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: Up to 10 supported PhD students and scientists per year. Supported R1-R4 categories in percentage: 25/40/25/10. Measurable indicator will be the number of supported PhD students/the number of students that applied for this type of support. Action 1. has high priority for both institutional strategy and HRS4R.
Current Status: In progress.
Remarks: The regulation on the mobility has been established.

Sub-Action 1.1
Title: Two-months stay of PhD student (Mgr. Martina Karasová, IBP employee) at University of Vienna
Mgr. Martina Karasová has been involved in the studies of mechanical stress on colon cells as well as in studies of the the influence of the combination of physical and chemical stimulation of cells on signal pathways activation. 
Timing: July 1, 2022 - August 31, 2022
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.1 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.2
Title: One-months stay of PhD student (Mgr. Pavlína Pokorná, IBP employee) at dr. Giovanni Bussi laboratory, Italy.
Mgr. Pavlína Pokorná has learned new method (enhanced-sympling MD simulation) and related types of analyses used in the laboratory. These methods are used in our department for the project of folding G-tracts. Collaboration with G. Bussi continues by the stay of his PhD student in our department. 
Timing: March 3, 2022 - April 29, 2022
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.2 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.3
Title: Mgr. Pavlina Pokorná participated at the conference "RNA Society Meeting", Boulder, Colorado, USA (the biggest world conference on RNA) in which bioinformatic groups take part.
Mgr. Pavlina Pokorná prezented a poster on the use of simulations for the study of RNA-protein complexes. Thanks to discussions with a broad spectrum of scientists, she acquired interesting ideas for her further work. She also meet dr. Campagne and discussed with him a joint project "Dynamics of FUS-RNA comlexes).
Timing: May 31, 2022 - June 5, 2022
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.3 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.4
Title: Mgr. Barbora Kvokačková participated at the symposium "Defining and defeating metastasis", Heidelberg, Germany.
This symposioum was held at the EMBL centre  and joint scintists of different fields focused to better understanding of tumour biology, first of all the processes of metastasis. Mgr. Barbora Kvokačková prezented a poster on her results obtained during PhD studies and discusses possible future collaborations with other participants. 
Timing: June 19, 2022 - June 22, 2022
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.4 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.5
Title: Mgr. Denis Šubert participated at the conference "Engineering recombinant proteins for structural and functional studies 2022", Liverpoole, UK.
This conference is focused to bioinformatic analysis of protein sequences as well as to methods of production, purification and quality control of proteins. Mgr. Denis Šuber prezented a poster on "DNA-binding preferences of the SAF-A protein in vitro".
Timing: November 10, 2022 - November 11, 2022.
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.5 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.6
Title: Mgr. Jan Mašek visited national parks of Austria searching for oligotrophic habitats with cyanobacteria.
This visit focused to newly discovered cyanobacterial siderophores - cyanochelines. The structure and its connection with function is investigated as well as its role in ecosystems (the cyanochelines enable microorganisms incorporation of iron in biologically acceptable form. During the visit samples of possible producents of cyanochelines have been collected for cultivation and  further analyses.
Timing: August 22, 2022 - August 25, 2022.
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.6 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.7
Title: Mgr. Klaudia Mrazíková participated at the conference WATOC 2020 (12th Triennial Congress of the World Association of Theoretical and Computational Chemists).
Mgr. Klaudia Mrazíková prezented a poster with her research results obtained in the frame of SYMBIT project. She discusses scientific topics with many specialists.
Timing: July 2 2022 - July 9, 2022.
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.7 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.8
Title: Mgr. Radka Vozárová stayed at Görlitz, Germany
Mgr. Radka Vozárová collected some samples for further analysis in the area called Weiβberg, where our dogroses (wild roses) of primary interest are growing there. They showed her how to use Flow Cytometer and MegaX for phylogeny tree construction and adding the calibration points into it. 
Timing: April 19, 2022 - May 3, 2022.
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.8 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.9
Title: Mgr. Radka Vozárová stayed at Gatersleben, Germany (prof. A. Houben's laboratory)
Mgr. Radka Vozárová learned different protocols and procedures on how to prepare material for immunocytochemistry. She also worked with Cytospin, which is a useful machine for slide preparation for FISH or immunocytochemistry.  There she tried to optimize the protocol for immunocytochemistry on pentaploid dogroses. She tried different centromeric histone H3 modifications on rosa mitotic and meiotic chromosomes, which we didn´t have in Brno.
Timing: May 3, 2022 - May 20, 2022.
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.9 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.10
Title: Mgr. Martin Stojaspal stayed at Edinburgh, UK
Mgr. Martin Stojaspal attended a workshop in Edinburgh, UK (Scotland) on 16-22th July, called "Introduction to Python for Biologists," which focused on introducing the Python programming language with lots of examples and exercises to practice the subject. The exercises were focused on issues that should help biologists to analyze their data. The workshop was delivered by teachers with experience in programming, who combined the explanatory part with the practical part very well. This workshop broadened my horizons in Python programming, which can be applied to facilitate day-to-day tasks in the lab, such as sequencing data analysis, cloning designs, etc. The trip was funded by a Twinning project, the funds of which I was able to use as a student at Masaryk University.
Timing: July 16, 2022 - July 22, 2022.
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.10 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.11
Title: Mgr. Alice Krumpolcová stayed at Botany Unit of Finnish Museum of Natural History, University of Helsinki, Finland.
Mgr. Alice Krumpolcová Collected Finnish populations of liverworts, DNA extractions, performed morphological studies of herbarium specimens, discussed and analysed liverwort phylogeny.
Timing: September 25, 2022 - October 28, 2022.
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.11 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.12
Title: "Internal Support of Mobility Program" has been elaborated to support mobility of PhD students in future (here).
Detailed information: The purpose of the Internal Support of Mobility Program of the Institute of Biophysics of the CAS, v. v. i. is to provide financial contributions to students of doctoral study programs traveling abroad for a study stay or practical internship in the duration at least 30 days. The contribution is intended primarily for students of doctoral study programs traveling abroad for study stays/practical internships organized within the framework of mobility programs of the parent university. For other types of mobility programs (e.g. trips organized by the IBP) it is possible to apply for a contribution, if that the trip is registered by a relevant study department of the parent university.
Timing: October 26, 2022
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category is supported. Action 1.12 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.13
Title: Mgr. Paolo Fagherazzi stayed at Max Delbrück Center for Molecular Medicine, Department of Genome diversification and integrity, superision: Dr. Michela Di Virgilio, Berlin, Germany
Detailed information: The stay was focused to defining the circular RNA component of Class Switch Recombination.
Timing: November 11, 2021 - February 2, 2022.
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.13 has high priority for both institutional strategy and HRS4R.
Current Status: In Progress

Sub-Action 1.14
Title: Mgr. Petra Raptová Ph.D. stays at Oulu, Faculty of Medicine, Finland.
Detailed information: She has visited the group of Prof. R. Hintall (children neurology, research unit PEDEGO, Faculty of Medicine at Oulu). This group is focused for a long time at heavy multiorgan neurological disorders at children. The research project, in which Mgr. P. Raptova will be involved, is focused at understanding of patophysiology of these disseases.
Timing: November 1, 2021 - January 1, 2022.
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: Young scientists R1-2 category are supported from ERASMUS. Action 1.14 has high priority for both institutional strategy and HRS4R.
Current Status: In Progress

Report for 2022
Title: Report on the mobility of PhD students (young scientists) in 2022
Detailed information: In 2022 we focus to the support of mobility of PhD students empoyed at the IBP. We have prepared a regulation for this activity (see here) to provide some financial support from the Institute for longer stays abroad of PhD students (at least 30 days). The competition will be announces by the Director of the Institute on December 1, 2022. In this year 12 PhD students stayed abroad: M. Karasová for 2 months, P. Pokorná for 1 month, P. Pokorná for 6 days, B. Kvokačková for 3 days, D. Šubert for 10 days, J. Mašek for 3 days, K. Mrazíková for 7 days, R. Vozárová for 14 days, R. Vozárová for 17 days, M. Sojaspal for 4 days, A. Krumpolcová for 1 month, P. Fagherazzi for 2 months. The short-term visits are mostly conferences.
Timing:  year 2022
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: 12 PhD students stayed abroad. Regulation for this activity has been prepared. R1 category is supported. Action 1. has high priority for both institutional strategy and HRS4R. 
Current Status for 2022: Completed for year 2022

Sub-Action 1.15
Title: Support of young researchers mobility by Internal Mobility Support Research Program (IMSRP)
Detailed information: Ph.D. students are strongly supported in our Institute. Their research (chemicals, measurements using infrastructure) as well as part time employment are covered from the budget of the Institute. In addition, the mobility is supported by the Internal Regulation (see Sub-Action 1.12). During their stays abroad, their positions are kept and salary remains covered in most cases.
Timing: January 20, 2023
Responsible unit: Council of the Institute, Steering Commitee and Working Group, Director of the Institute
Indicator(s)/Targets: Mobility is supported using the regulation described in 1.12. Director of the Institute, Eva Bártová, decided to provide support according to the IMSRP to 2 students:  R. Mikesova: Sweden, Umea University (see Sub-Action 1.19) and O. Hesko: Slovenia, Lublan, National Institute of Chemistry (see Sub-Action 1.16). Sub-Action 1.15 has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.16
Title: One-months stay of PhD student (Ing. Ondrej Hesko, IBP employee) at Analytical Chemistry Laboratory, National Institute of Chemistry, Lublan, Slovenia.
Detailed information: Ing. Ondrej Hesko has been involved in the development of a sensitive and selective electrochemical genosensor for field detection of citrus bark cracking viroid (CBCVBd). The internship was also focused on learning the electrochemical impedance spectroscopy method as a tool for the detection of nucleic acid hybridization and developing cooperation with the Chemical Institute in Slovenia.
Timing: February 27, 2023 - March 31, 2023
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.16 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.17
Title: Three-months stay of PhD student (Mgr. Marie Kratka, IBP employee) at Max-Planck-Institut für Pflanzenzüchtungsforschung, Cologne, Germany. The program of the internship of Mgr. Marie Kratka was the creation of a recombination map of the holocentric plant of the wild bull by means of pollen scRNA analysis.
Timing: March 14, 2023 - June 16, 2023
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.17 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.18
Title: Two-months stay of PhD student (Ing. Tatiana Staronova, IBP employee) at Ruđer Bošković Institute, Zagreb, Croatia.
Detailed information: Under the leadership of Dr. In Strmečki Kos, Ing. Tatiana Staronova dealt with the electrochemical analysis of unlabeled polysaccharides occurring primarily in seawater. Since carbohydrates can often be found in nature covalently bound to proteins, peptides or lipids, she also studied various mixtures of these substances and looked for optimal methods and conditions for their analysis.
Timing: March 23, 2023 - May 30, 2023
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.18 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.19
Title: One-month stay of PhD student (Mgr. Tereza Mikesova, IBP employee) at Umea University, Umea, Sweden.
Detailed information: During the internship, Mgr. T. Mikesova worked on two methods that are intended for a more detailed description of guanine quadruplexes in combination with other common biophysical methods. These are qPCR stop assay and primer extension assay. The result of both of these methods is the determination of the stability of guanine quadruplexes, the presence of which affects to varying degrees the ability of DNA polymerase to synthesize a DNA strand. The advantage of the qPCR stop assay method is the possibility to analyze genomic DNA isolated from cells. The advantages of the primer extension assay method are analyzes starting at a temperature of 20 °C, depending on the selected DNA polymerase, and the possibility of determining the guanines involved in the formation of a given guanine quadruplex. Another positive of this internship is the establishment of scientific cooperation and the implementation of methods at the DBNA department. Both methods will be included in upcoming publications.
Timing: April 3, 2023 - May 7, 2023
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.19 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.20
Title: Two-months stay of PhD student (MSc. I. Indu, IBP employee) at Geneton. s.r.o., Bratislava, Slovakia. Detailed information: During the internship MSc. I. Indu learnt the techniques of next-generation sequencing and Sanger sequencing, performed experiments of library preparation for Truseq DNA sequencing and Nextera XT Illumina sequencing, quantification, EMSA.Genomic and cell-free DNA isolation. She also gained experience the
preparation of Electrophoretic Mobility Shift Assay for Protein (SG4) human DNA interaction.
Timing: September 2, 2023 - November 2, 2023
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.20 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.21
Title: One-month stay of PhD student (Ing. Lucie Sislerova, IBP employee) at Medical University of Graz, Graz, Austria.
Detailed information: The internship at MedUni Graz took place in the research team of Pedro Sanchez Murcia. Ing. L. Sislerova focused mainly on modeling non-B DNA structures (e.g. G-quadruplexes) and their interaction with small molecules mainly by methods molecular dynamics.
Timing: September 11, 2023 - October 11, 2023
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.21 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.22
Title: One-month stay of PhD student (Mgr. Jiri Rudolf, IBP employee) at Medical University of Graz, Graz, Austria.
Detailed information: Mgr. J. Rudolf has mastered two RNA separation methods that have been applied to plant samples to isolate plant telomerase RNA. An annex separation protocol was optimized for plant RNA. This procedure was successful for the separation of the target fraction from tRNA and long rRNA. The project was consulted several times with Prof. Mark Helm, who agreed to the possibility of long-term cooperation. The method can be converted to the workplace.
Timing: October 6, 2023 - November 6, 2023
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.22 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.23
Title: One-month stay of PhD student (Mgr. Anna Rudolf, IBP employee) at Medical University of Graz, Graz, Austria.
Detailed information: As part of the internship at IMB Mainz, a detailed introduction to the individual-nucleotide resolution crosslinking and immunoprecipitation method took place (iCLIP) in in vivo and in vitro variants. Furthermore, own optimization experiments with proteins associated with telomerase were started, so that this approach could possibly be applied in telomerase projects at the home workplace, and serve for a more detailed description of RNA-protein interactions.
Timing: October 6, 2023 - November 6, 2023
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category was supported. Action 1.23 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 1.24
Title: Four-month stay of PhD student (Mgr. Jakub Červinka, IBP employee) at University of Copenhagen, Denmark.
Detailed information: Mgr. J. Červinka will learn new methods in the field of cell biology such as cultivation of cells from patient samples in the form of spheroids and subsequent study of their sensitivity to anti-tumour drugs.
Timing: January 1, 2024 - May 7, 2024
Responsible Unit: HR Award Team, Director of the IBP
Indicator(s)/Targets: R1 category is supported. Action 1.24 will have high priority for both institutional strategy and HRS4R.
Current Status: In Progress

Report for 2022-2023
Title: Report on the mobility of PhD students (young scientists) in 2022-2023
Detailed information: In 2022 we focus to the support of mobility of PhD students empoyed at the IBP. We improved working conditions of the students in order to stimulate internships abroad. In addition, we have prepared a regulation for this activity (Intranet, see Sub-Action 1.12) to provide some financial support from the Institute for longer stays abroad of PhD students (at least 30 days). The competition has been announces by the Director of the Institute on December 1, 2022.
In 2022 year 12 PhD students stayed abroad: M. Karasová for 2 months, P. Pokorná for 1 month, P. Pokorná for 6 days, B. Kvokačková for 3 days, D. Šubert for 10 days, J. Mašek for 3 days, K. Mrazíková for 7 days, R. Vozárová for 14 days, R. Vozárová for 17 days, M. Sojaspal for 4 days, A. Krumpolcová for 1 month, P. Fagherazzi for 2 months. The short-term visits are mostly conferences.
In January, 2023, the mobility has been supported based on the regulation for 2 students: R. Mikesova: Sweden, Umea University, 3.4.-3.5.2023, O. Hesko: Slovenia, Lublan, National Institute of Chemistry, 27.2.2023 - 31.3.2023. 6 Ph.D. students visited laboratories abroad without using financial support from the Institute based on the regulation (Mgr. M. Kratka, MSc. I. Indu, Mgr. J. Rudolf, Mgr. A. Rudolf, Ing. T. Staronova and Ing. L. Sislerova). The work at the institute before and after the internship was thematically related to the work done during the internship and was financed by the institute. During the internship, the salary of the students is maintained by the institute. In December, 2023, a four-month stay of Mgr. J. Červinka has been supported at University of Copenhagen, Denmark.
Timing:  2022-2023
Responsible Unit: HRAW Working Group, HRAW Expert Team, Director of the Institute
Responsible Sub-Group: Stanislav Kozubek, Pavlína Pokorná, Iva Kejnovská, Martin Falk
Indicator(s)/Targets: 12 students and scientists stayed abroad (4 over 1 month) in 2022; 8 students stayed abroad for one month or loner in 2023, 3 students have been supported on the base of the new regulation in 2023. Regulation for this activity has been prepared. R1-R4 categories were supported. Measurable indicator (the number of students supported/the number of students requesting for the support) has been fulfilled to 100%. Action 1. has high priority for both institutional strategy and HRS4R. We will continue with this Action in the next period (2024-2026) in order to optimize the regulation and support the mobility in appropriate form corresponding to the needs of students and scientists as well as to the financial possibilities of the Institute.
Current Status for 2022-2023: Completed for 2022-2023.
Status of the Action: Will be continued in 2024-2026.

Action 2. (text from the Action Plan)
Title: Recruitment tool - the external part containing job advertisements
GAP Principles: 4, 10, 12, 13, 14, 15
Timing: Implementation of the tool: 2022, the last quarter; In the period 2022-2024, each year information on recruited scientists will be provided at the last qarter of the year.
Responsible Unit: HR Award Team; ISAB members, Attestation Commission
Indicator(s)/Targets: Indicators: 10-20 newly-recruited scientists each year; R1-R4 categories will be supported, approximately 40/30/20/10 in percentage. Measurable indicator will be the number of recruited scientists/the number of scientists needed. The external part of the recruitment tool containing job advertisements will be adjusted and will contain web links to information on institution working conditions, benefits, etc. The part of the recruitment tool used for communication with candidates will be sophisticated and will allow for automatic feedback and other communication patterns. Department leaders will be selected based on fully open recruitment activity advertised in scientific journals. Action 2. has high priority for both institutional strategy and HRS4R. 
Current Status: In progress
Remarks:

Sub-Action 2.1
Title: New PhD position in plant evolution genetics
Timing: February 2, 2022, deadline February 25, 2022 14 h
Indicator(s)/Targets: Recruitment of PhD student to the Department of dr. R. Hobza. The student (Jan Mašek) has been selected from 9 candidates and employed starting from March 1, 2022.
Detailed descriprion: PhD position in Dr. Hobza laboratory was advertised in February 2022 on the IBP webpage and international  job portal (Euraxess). Moreover, in order to find a highly motivated and ambitious PhD candidate the information was spread in social and university networks and during our teaching activities. Unfortunately, we have received only 8 applications in total.  The selection committee (Dr. Roman Hobza, Dr. Lucie Kajan Grodecká, Dr. Vojtěch Hudzieczek) was instructed by Ing. Robin Ulrich on HRAW recruitment rules and made an unbiased and non-prioritized assessment of the academic qualifications and experience with respect of research area, techniques, skills, and other requirements listed in the advertisement. We found only one application meeting our requirements. The candidate (Jan Mašek) was carefully interviewed and found fully eligible to become a part of our team. Action 2.1 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.2
Title: Position of the director of the Institute
Timing: January 28, 2022, deadline March 4, 2022 14 h
Indicator(s)/Targets: We have received documents from only 1 candidate, Prof. Eva Bártová, DSc. On March 14, 2022 the Academic Commission elected Prof. Eva Bártová for the second term, which was approved by the Council of the Institute as well as by the Council of the Czech Academy of Sciences. Action 2.2 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.3
Title: New postdoc position in cell biology and radiobiology
Timing: November 25, 2021, deadline December 22, 2021 14 h
Detailed description: Six candidates applied for the postdoctoral competition. They were all from outside the EU. Three of them did not meet the conditions of the procedure due to their education. From the three candidates, a selection of other criteria related to professional experience required in the announced tender was then made. Based on the assessment of the documents of individual candidates, Anicet Batcho was invited to the interview. The relaxation of anti-covid measures enabled the selection committee (instructed by Ing. Robin Ulrich on HRAW recruitment rules) composed of E. Sýkorová, J. Fajkus, V. Peška, L. Jenner to meet with the applicant at the Institute of Biophysics. After the interview, the commission assessed the candidate's answers and presentations, and after the meeting, he was accepted for the position. The tenderer was informed of the outcome of the procedure by e-mail. 
Indicator(s)/Targets: Recruitment of postdoc to the Department of dr. M. Falk. The student (dr. Batcho Agossa Anicet) has been selected from 6 candidates and employed starting from March 28, 2022 Action 2.3 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.4
Title: New PhD position in DNA replication, genome stability and cancer development (advertisement)
Timing: March 11, 2022, deadline April 15, 2022 14 h
Detailed description: PhD position in Dr. Polasek-Sedlackova laboratory was advertised on 11^th March 2022 on the IBP webpage, international and national job portals, and social networks in order to find a highly motivated and ambitious PhD candidate. After application deadline 15^th April 2022, all applications (93 in total) were carefully screened, and 24 applications were excluded due to missing documents required in the application. The selection committee (Mgr. Hana Polasek-Sedlackova, Ph.D., Mgr. Jana Krejci, Ph.D.) made an unbiased and non-prioritized assessment of the academic qualifications and experience with respect of research area, techniques, skills, and other requirements listed in the advertisement. Additionally, the selection committee was instructed by Ing. Robin Ulrich on HRAW recruitment rules and acted in a way that promotes the impartiality and diversity of the laboratory environment regardless personal background of applicants. Subsequently, between 20^th and 21^st April 2022, 11 candidates were invited to the online interviews, during which each candidate presented his/her master project and career path, became acquainted about research program of Dr. Polasek-Sedlackova group, and received detailed information about offered PhD position and PhD program. On 25^th April 2022, the second round of online interviews with four candidates took place, from whom Anoop Kumar Yadav was selected as the best candidate meeting all the requirements for the announced position. Once assessment work was completed, the selection committee provided feedback on the interview to those candidates who showed the interest. 
Indicator(s)/Targets: Recruitment of PhD student in the frame of Junior Star project. Action 2.4 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.5
Title: New postdoc position in animal and human physiology
Timing: June 16, 2022, deadline  July 8, 2022 23 h
Detailed description: Position of professional staff (researcher), working place in the Department of Biophysics of the Immune System, fully funded position with competitive salary in a well-established laboratory (full-time job), the contract will be fixed till December 31, 2022 with possible prolongation. Participation on interdisciplinary project focused on development of hyaluronan based materials, testing in vivo with mice, different types of surgical procedures will be performed, ingernational team with a strong publication track record and international collaboration. The applicant should have a solid knowledge of animal and human physiology with special focus on innate immune system response. Previous exposure to basic methods of biochemistry and molecular biology and other advanced techniques will be advantageous. The expertise of the applicant in the testing of medical devices and new therapeutics should cover the following: master of science in animal or human physiology, advanced experience in mice surgical procedures, evaluation of material biocompatibility in vivo, certificate of professional competence for designing experiments and experimental projects on animals (EU validity), good level of communication in English language (verbal and written). Personal characteristics: highly motivated, independent thinking, good organizational and communication skills, ability to develop and apply new concepts, creative approach to problem-solving, flexible attitude. 

After the application deadline the applications were carefully screened. The selection committee (Assoc. Prof., L. Kubala, Ph.D., Ing. Robert Ulrich) was instructed by Ing. Robin Ulrich on HRAW recruitment rules and made an unbiased and non-prioritized assessment of the academic qualifications and experience with respect to the research areas. Based on good laboratory experience and skills Mgr. Eva Kriváková has been employed for a period August 1, 2022 - December 31, 2022.
Indicator(s)/Targets: Recruitment of postdoc to the Department of Prof. L. Kubala. Starting date: August 1, 2022. Action 2.5 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.6
Title: New postdoc position in DNA replication and genome stability
Timing: June 30, 2022, deadline  July 31, 2022 23 h
Detailed description: The Department of Cell Biology & Epigenetics is looking for talented candidates, who are interested in joining our department as a postdoctoral fellow. Postdoctoral fellow will be affiliated with the laboratory of Dr. Hana Polasek-Sedlackova at the Department of Cell Biology and Epigenetics, Institute of Biophysics, Czech Academy of Sciences. The research program of Polasek-Sedlackova group bridges basic DNA replication research with cancer research and developmental biology field. Our goal is to understand how DNA replication is regulated in mammalian cells to achieve high fidelity of copying genomes, critical to alleviate genome instability associated with severe diseases, including cancer. By combining physiologically relevant cellular models with state-of-the-art quantitative cell biology, genomics, and proteomics approaches, we explore the regulation of genome duplication during normal mammalian development and malignant transformation. The role of the postdoc: As a postdoctoral fellow, you will be engaged in ambitious and interdisciplinary research project. You will explore the molecular mechanisms ensuring precise and timely regulated initiation of DNA replication¾a very early steps laying the foundation for error-free genome duplication. You will learn and fully master the state-of-the-art approaches of quantitative cell biology including CRISPR-Cas9 mediated genome editing, high-resolution microscopy and high-content imaging. You will also have an opportunity to develop your own ideas within our research program. We offer:(1) A two-year postdoctoral position in a stimulating and supportive international research environment. (2) Access to state-of-the-art facilities and infrastructure.  (3) A competitive salary with health insurance and social security and additional benefits (five weeks of paid vacation, sick days, free childcare directly at the institute, meal allowance, sport, and recreation contribution etc.). (4) For international candidates, we offer assistance and support with practical and legal aspects (housing, visa, tax etc.). (5) Opportunity to interact with our network of national and international collaborators. We are looking for a highly motivated and ambitious postdoc candidate with: (1) A PhD degree in Life Science e.g., Biochemistry, Biomedicine, Molecular Biology, Protein Science or similar. (2) Good record of peer-reviewed scientific publications. Pre-prints are also counted to meet this requirement. (3) Hands-on experience in molecular cloning, cell culture work, and microscopy-based approaches is required. (4) Analytical ability to design innovative scientific or technical solutions. (5) Strong communication and collaborative skills and an interest to work in international and interdisciplinary environment. (6) Proficiency in spoken and written English. Application must include following documents: (1) A letter stating your specific scientific interest, motivation, and qualifications for the project (max. two pages). (2) Detailed CV, including personal contact information, education, work/research experience, laboratory skills, list of publications or manuscripts (max. two pages). (3) Copies of PhD diploma and master’s diploma. If you are waiting for a PhD diploma, provide a written statement from the supervisor. (4) At least one signed reference letter (with referee contact details and relationship). 
       After the application deadline of 31^st July 2022, all applications (10 in total) were carefully screened for the criteria required for the postdoc position. The selection committee (Mgr. Hana Polasek-Sedlackova, Ph.D., Ing. Robert Ulrich) was instructed by Ing. Robin Ulrich on HRAW recruitment rules and made an unbiased and non-prioritized assessment of the academic qualifications and experience with respect to the research area, and techniques, skills, and other requirements listed in the advertisement. Additionally, the selection committee acted in a way that promotes the impartiality and diversity of the laboratory environment regardless personal background of the applicants. Subsequently, between 5^th and 9^th August 2022, three candidates were invited to the online interviews, during which each candidate presented his/her Ph.D. project and career path, became acquainted with the research program of Dr. Polasek-Sedlackova group, and received detailed information about offered postdoc position. Based on very good laboratory experience and skills necessary to successfully drive the offered postdoc project, Ing. Magdalena Skalníková, Ph.D. was selected as the best candidate for this position. Once assessment work was completed, the selection committee provided feedback on the interview to those candidates who showed interest.
Indicator(s)/Targets: Recruitment of postdoc to the Department of prof. E. Bátrová. Starting date: November 1, 2022. Action 2.6 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.7
Title: New postdoc position in DNA repair studies
Timing: July 11, 2022, deadline  September 15, 2022 17 h
Detailed description: The Department of Cell Biology & Epigenetics is looking for a postdoctoral fellow in the laboratory of Dr. Eva Bártová, the Department of Cell Biology and Epigenetics, Institute of Biophysics, Czech Academy of Sciences. The department is interested in the studies of the structures and processes in the cell nucleus. We are focused on nuclear structures which are involved in transcription or DNA repair. Another field of our research is the study of epigenetic events in the cell nucleus. We aim at post-translation modifications of histones (PTMs). We study the regulatory role of PTMs of histones. We investigate nuclear processes by the use of molecular biology or proteomics techniques. In addition, high-resolution confocal microscopy, combined with the GFP technique, enables us to investigate processes in living cells, for example, during cell differentiation. The main part of our research is focused on DNA repair studies in living cells exposed to UVA or gamma-radiation. Using UV lasers, we are able to induce DNA lesions in the selected regions of the genome (see image). Therefore, we are able to observe protein complexes playing a role in DNA damage response. Recently, our studies were focused on the role of RNA modification in DNA damage response. Our preferences: Ph.D. degree in Biochemistry, Biomedicine, Cell and Molecular Biology. Applicants with good skills in ChIP-PCR, ChIP-Seq, and western blots are preferred. Also, experience in confocal microscopy, FRAP, and FLIM-FRET are demanded. Only applicants with the scientific potential to apply for postdoctoral projects will be selected for the interview. For this prerequisite, an excellent scientific score is essential. The most important aspect: Please, if you are interested in an interview, send to Eva Bartova (bartova@ibp.cz) an example of your representative confocal images, western blots, ChIP-PCR data, FRAP or FLIM data. Confocal images are preferred, especially in 3D-mode, deconvolution, or super-resolution. We offer: 1) A postdoctoral position in a stimulating and supportive international research environment, 2) Access to state-of-the-art facilities and infrastructure, 3) A competitive salary with health insurance and social security and additional benefits (five weeks of paid vacation, sick days, 10% home office, free childcare directly at the Institute, meal allowance, sport and recreation contribution, etc.), 4) For international candidates, we offer assistance and support with practical and legal aspects (housing, visa, tax, etc.). We offer two months’ accommodation at the Institutional dormitory, till all mentioned aspects are solved. The application must include the following documents: 1) A letter stating your specific scientific interest, motivation, and qualifications for the project (max. two pages), 2) A detailed CV, including personal contact information, education, work/research experience, laboratory skills, list of publications or manuscripts (max. two pages), 3) Copies of Ph.D. diploma and master’s diploma. If you are waiting for a Ph.D. diploma, provide a written statement from the supervisor, 4) At least one signed reference letter (with referee contact details and relationship). Completed applications must be sent as one pdf file to ulrich@ibp.cz and bartova@ibp.cz  by September 15^th, 2022. Selected candidates will be invited for an online interview in the first half of October.

On the basis of a professional assessment of the qualification requirements, taking into account the results of the previous scientific activities of the applicants (dr. Muhammad Bilal, dr. Mozzammel Haque, dr. Sweta Singh, dr. Kateřina Teturová, dr. Vlastimil Tichý, dr. Hemendra Yadav) and subsequent debates with head of the Department of Cell Biology and Epigenetics, Assoc. Prof. RNDr. Eva Bártová, Ph.D., DSc. the selection committee (instructed by Ing. Robin Ulrich on HRAW recruitment rules) recommends the director of the IBP CAS to accept to the Department as a researcher Mgr. Vlastimil Tichý, Ph.D., who, according to the commission's conclusions, best meets the requirements for the given job position.

Indicator(s)/Targets: Recruitment of postdoc to the Department of prof. E. Bátrová. Starting date: September 15, 2022. Action 2.7 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.8
Title: New PhD position in unusual secondary structures of nucleic acids
Timing: July 27, 2022, deadline  August 17, 2022 23 h
Detailed description: PhD student (R1), part-time with 0.4 workload – 16 h/week at the Department of Biophysics of the Nucleic Acids for the project focusing on the unusual secondary structures of nucleic acids and their interactions with proteins and small-molecule ligands. Requirements: 1) student of a doctoral programme in Biophysics, Biochemistry, Chemistry or Molecular Biology at any of Czech universities; 2) knowledge of spectroscopic and electrophoretic methods; 3) knowledge of the respective field of nucleic acids structure; 4) written and spoken English language (level B2 minimum). Gross salary at 0.4 workload 11,000 CZK/month. Until December 31st, 2022, with expected one-year annual extensions. The applicant should send a CV and a cover letter to the group leader, Daniel Renciuk (renciuk@ibp.cz) and to a Head of economic administration, Robert Ulrich (ulrich@ibp.cz) before August 17th, 2022.

After the application deadline of August 17, 2022, all applications (15 in total) were carefully screened for the criteria required for the PhD position. The selection committee (Mgr. Daniel Renčiuk, Ph.D., Ing. Robert Ulrich) made an unbiased and non-prioritized assessment of the academic qualifications and experience with respect to the research area, and techniques, skills, and other requirements listed in the advertisement. The selection committee instructed by Ing. Robin Ulrich on HRAW recruitment rules  recommended Mgr. Filip Křikava to be employed at the Department. Once assessment work was completed, the selection committee provided feedback on the interview to those candidates who showed interest.
Indicator(s)/Targets: Recruitment of PhD student to the Department of Biophysics of the Nucleic Acids. Starting date: September 1, 2022. Action 2.8 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Report for 2022
Title: Report on the recruitment of scientists and PhD students to the Institute (activities in 2022)
Detailed informationIn: In 2022 we have advertised and subsequently selected 8 candidates to various positions from Ph.D. positions (3 candidates – Vlastimil Tichý, Anoop Kumar Yadev, Jan Mašek), postdoc position (4 candidates – Filip Křikava, Eva Krivaková, Magdalena Skalníková, Batcho Adoosa Anicet) and to the postition of the director of the Institute (1 candidate – Eva Bártová). The number of applications was in average 7 with limits 1-15 candidates. In order to fulfill the OTM-R principles, the advertisements were published at the Institute web pages as well as Euraxess, with detailed description of the position (the field of work, period, required experience, knowledge of languages, salary and other conditions). In the advertisements the required documents were also listed. After the application deadline the candidates were carefully screened for the criteria of the position. The selection committee was instructed by Ing. Robin Ulrich on HRAW recruitment rules and made an unbiased and non-prioritized assessment of the academic qualifications and experience with respect to the research area, technical skills, and other requirements. Subsequently, the selected applicants were invited to the interviews with presentations, they also received detailed information about the offered position. The winning candidates were selected exclusively on the merit (experience and good laboratory skills in relation to the future research).
The selection of the director of the Institute is regulated by the academic rules (selection committee is nominated by the Council of the Academy of Sciences). The requirements as well as the procedure has been discribed at the web pages of the Institute, Academy of Sciences, at Euraxess and in Czech newspaper.
A new internal regulation on the recruitment and selection of researchers of the Institute of Biophyiscs of the CAS has been adopted in September 16, 2022. The basics OTM-R principles are involved in this document and the future recruitments will be realized according to this regulation. The regulation can be seen here.
Timing:  year 2022
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: The number of recruitments (8) as well as the spectrum of positions (R1-R4) has been approximatelly fulfilled. R1/R2/R3/R4 was 3/4/0/1, which corresponds to the expected percentages (40/30/20/10). Measurable indicator (the number of recruited scientists/the number of scientists needed) has been fulfilled to 100%. The OTM-R principles were respected (see the detailed description) and substantially improved during the year. The communication tools used involved presentations in the Institute as well as interviews throught on-line tools (Zoom or other platforms). Action 2. has high priority for both institutional strategy and HRS4R. 
Current Status for 2022: Completed for 2022

Sub-Action 2.9
Title: New postdoc position (R2)
Timing: January 1, 2023, deadline, Starting date March 1, 2023
Detailed description: The research group headed by Dr. Karel Souček conducting a basic and translational research in the field of cancer biology invites scientists to apply for a postdoctoral position. We wish to understand the plasticity of cancer cells in the context of tumor heterogeneity and progression. We consistently strive to publish our findings in reputable scientific journals, develop newmethods and collaborate with clinicians to be able to translate our research results to practice. The key components of our daily activities include collaboration between experimentalists, medicinal chemists and clinicians, solidarity among the laboratory team and mentoring of young colleagues. Project annotation: Haspin is an atypical Ser/Thr kinase with a well-described function in normal mitosis, but a largely understudied role in regulating cell cycle interphase, plasticity and cell fate decisions. The project will focus on elucidating differences in the Haspin interactome in interphase and mitosis and its role in cell cycle regulation, plasticity and fate. The research will combine several state-of-the-art methodologies (advanced proteomics, unique chemical probes) into unbiased and hypothesis-driven experimental strategies with the ambition to address important gaps in our understanding of Haspin function, molecular mechanism and regulation in fundamental biological processes. The goal is to advance our understanding of the precise role of this kinase in multiple aspects and contexts and to address its attractiveness as a therapeutic target. Requirements: be self-motivated, independent, team-oriented;have received a PhD or its equivalent within the last 7 years;have a publishing record – in the last three years at least two publication outputs. The applicant must be the principal author of at least one publication; have experience in field molecular and cell/cancer biology, biochemistry, or biophysics; have experience with research in (cancer) cell cycle and mitosis (an advantage); have excellent communication skills and the ability to collaborate with multiple teams. Application should involve: CV (max. two A4 pages) including a summary of work experience, publication activity, involvement in research grants, etc; a cover letter describing motivation and previous experience; contact information to at least three referees; send applications to Karel Souček at ksoucek@ibp.cz. 
Dr. Karel Souček appointed a commission which after careful consideration of all documents decided to select candidates for narrower selection: Marine Serrano, Alejandru Leyton, Jana Szabova and Natalia Gablo. After on-line discussions with the candidates, the commission (instructed by Ing. Robin Ulrich on HRAW recruitment rules) recommended Marina Serrano for the postdoc position in the group of dr. K. Souček with the starting date March 1, 2023. After a short time Marine Serrano had problem with her family and decided to end the work in the Institute.
Indicator(s)/Targets: Recruitment of R2 researcher the Department of Cytokinetis had high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.10
Title: New postdoc position in the group of Molecular DNA Complexes (Department of Cell Biology and Radiobiology)
Timing: deadline June 29, 2023, starting date July 1, 2023
Detailed description: We are established research team interested in the function and evolution of telomere and telomerase in plants. We focus on telomerase function during plant growth and vegetative development as well as on telomerase interactions in vivo and in vitro to establish working models. The successful candidates will join projects that combine methodical approaches of plant developmental genetics,  molecular biology, microscopy and genetics. Requirements: PhD in molecular biology, genetics, biochemistry, or a related discipline, PhD thesis defence in early 2023 is also acceptable; practical experience with plant models and plant handling; publication and track record showing the candidate’s profile; routine skills in using molecular biology/biochemistry methods (electrophoresis, isolation DNA/RNA/protein, hybridization, PCR/qPCR, western blotting, immunoprecipitation); practical experience with RNA and/or microscopy is a plus; proficiency in English – oral and written; openness to learn new techniques; active attitude to problem-solving, ability to work in a team; independent thinking & passion for science, ffer: cutting-edge research projects; professional career development & soft skills; international collaboration & visibility; english speaking, stimulating and friendly environment; benefits package (5 weeks of paid holiday, institute canteen, children and sport facilities); work-life balance in university city offering options for outdoor and cultural activities. Please submit your structured CV including list of publications, motivation letter and name & contact details of academic referees via e-mail to evin@ibp.cz and ulrich@ibp.cz before January 6th, 2023. Interviews with selected applicants can be arranged online, when appropriate.
The evaluation committee was instructed by Ing. Robin Ulrich on HRAW recruitment rules and involved Mgr. E. Sýkorová, Prof. J. Fajkus, Prof. M. Fojtova. 11 candidates applied for this position, however, the committee concluded that the conditions mentioned above fulfilled ony 2 of them (the other were informed about the conclusions of the committee). Both selected candidates (Mgr. Anna Korytářová and Mgr. Jiří Rudolf) were interwiewed and finally they were employed from July 1, 2023 to December 31, 2023.
Indicator(s)/Targets: Recruitment of PhD students to the Department of Cell Biology and Radiobiology has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.11
Title: New Ph.D. position (R1 researcher) in DNA replication, genome stability and cancer development
Timing: deadline  March 15, 2023, 23 h
Detailed description: The Department of Cell Biology & Epigenetics invites applications from young talented candidates, who are interested in joining our department as a Ph.D. fellow. Ph.D. fellow will be affiliated with the laboratory of Dr. Hana Polasek-Sedlackova at the Department of Cell Biology and Epigenetics, Institute of Biophysics, Czech Academy of Sciences and Ph.D. program Molecular and Cell Biology and Genetics, Faculty of Science, Masaryk University. The position is available from 1st October 2023 or as soon as possible thereafter. Application deadline: 15th March 2023. As a Ph.D. fellow, you will be engaged in an ambitious and interdisciplinary research project. You will explore the molecular mechanisms ensuring precise and timely regulated initiation of DNA replication – a very early steps laying the foundation for error-free genome duplication. You will learn and fully master the state-of-the-art approaches of quantitative cell biology including CRISPR-Cas9 mediated genome editing, high-resolution microscopy, and high-content imaging. You will also have an opportunity to develop your own ideas within our research program. We offer: 1) A four-year Ph.D. position in a stimulating and supportive international research environment, 2)access to state-of-the-art facilities and infrastructure, 3) opportunity to interact with our network of national and international collaborators, 4) a competitive salary with health insurance and social security and additional benefits (five weeks of paid vacation, sick days, free childcare directly at the institute, meal allowance, sport and recreation contribution, etc.), 5) for international candidates, we offer assistance and support with practical and legal aspects (housing, visa, tax, etc.). We are looking for a highly motivated and ambitious Ph.D. candidate with: 1) a Master’s degree in Life Science e.g. Biochemistry, Biomedicine, Molecular Biology, Protein Science, or similar, 2) basic knowledge and lab experience with molecular and cell biology techniques, 3) strong communication and collaborative skills and an interest to work in an international and interdisciplinary environment, 4)  proficiency in spoken and written English. The application must include the following documents: 1) a letter stating your specific scientific interest, motivation, and qualifications for the project (max. two pages), 2) detailed CV, including personal contact information, education, work/research experience, laboratory skills, publications, or manuscripts (max. two pages), 3) copies of diplomas, Bachelor as well as Master’s degrees including the transcript of grades. If you are waiting for a Master’s diploma, provide a written statement from the supervisor, 4) at least one signed reference letter (with referee contact details and relationship). Complete applications must be sent as one pdf file to ulrich@ibp.cz and polasek-sedlackova@ibp.cz by the 15th of March. Selected candidates will be invited for an online interview in the third week of March. For more information, please contact Dr. Hana Polasek-Sedlackova (polasek-sedlackova@ibp.cz).
A total of 104 applicants, mainly from abroad, took part in the selection process. On the basis of non-fulfillment of qualification requirements (missing required documents, etc.), 28 applicants were excluded from further selection. Subsequently, the selection committee (instructed by Ing. Robin Ulrich on HRAW recruitment rules) involved researcher of the project GAČR JUNIOR STAR 22-20303M (Deciphering the beginnings of DNA replication in the integrity of the genome) Mgr. Hana Polášek-Sedláčková, Ph.D. together with her scientific team (M. Skalníková, A. K. Yadav, J. Krejčí) based on expert assessment, selected a total of 10 candidates who best met the requirements for the given job position. Subsequently, on the March 22-23, 2023, online interviews took place, on the basis of which to the second round of the selection process proceeded: Shazia Ashraf (University Hospital Erlangen, Germany), Khalid Rasheed (Institute Curie, France), Markéta Dvořáková (Palacký University, Czech Republic) and Simran Negi ( Indian Institute of Science, India). On March 27, 2023, the final online interviews took place with members of the research group of Dr. Polášek-Sedláčková. The final round of the selection process took place on March 27-30, 2023 in writing, when all candidates prepared a short description of the future doctoral project. After evaluating the written papers, Simran Negi was selected as the best candidate who met all the requirements for the advertised position. On the basis of ongoing expert consultation with the researcher of the GAČR JUNIOR STAR 22-20303M project  Mgr. Hana Polášek-Sedláčková, Ph.D. and after a thorough study of the qualifications of the applicants, the selection committee recommends the director of the BFÚ of the Academy of Sciences of the Czech Republic to accept the candidate Simran Negi as a doctoral student in the GAČR JUNIOR STAR 22-20303M project from September 1, 2023, subject to the completion of the necessary formalities for doctoral studies in the Czech Republic.
Indicator(s)/Targets: Recruitment of PhD candidate to the Department of Assoc. Prof. Eva Bártová. Starting date: September 1, 2023. Action 2.11 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.12
Title: New Ph.D. position in cancer research
Timing: application deadline March 31, 2023 23:59 (Europe/Prague) h
Detailed descriprion:  What we offer: 1) position in cancer research for 4 years, 2) funded studentship combined with part time grant position, 3) independently funded applications welcomed, 4) superb admin and tech support. Research Area: cancer cell plasticity and its dynamics, circulating tumor cells, novel drug candidates. We are looking for and independent, self motivated and patient person with an interest in cell and tumour biology. The applicants should send CV and a short motivation letter, including scientific interest and future plan, diploma thesis and contacts of the current supervisor and co-supervisor to Karel Souček (ksoucek@ibp.cz) by March 31, 2023. Selected candidates will be invited for an interview in the first week of April 2023.
A total of 29 applicants took part in the selection process. Dr. Karel Souček appointed a commission (instructed by Ing. Robin Ulrich on HRAW recruitment rules) which after careful consideration of all documents decided to select Mgr. Janu Vepřek, however, she refused the offered employment. The other candidates did not fulfill the requirements of the commission.
Indicator(s)/Targets: 4 year PhD position in cancer research under the umbrella of the Ph.D. program Animal Physiology, Immunology and Developmental Biology. Action 2.12 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.13
Title: New postdoc position in cell biology for a project aimed at investigating the function of Haspin kinase and its role in the regulation of cell cycle, plasticity, and fate.
Timing: Starting Date: July 25, 2023, deadline May 25, 2023
Detailed description: Are you a recent PhD graduate in molecular and cell biology, biochemistry, or biophysics looking for an exciting postdoctoral opportunity? Join our team for a project aimed at investigating the function of Haspin kinase and its role in the regulation of cell cycle, plasticity, and fate. We are seeking a highly motivated and enthusiastic candidate with a PhD in the relevant fields. Prior postdoctoral experience is not required; we welcome candidates who are eager to learn and have a strong passion for research. Good communication skills and the ability to collaborate with multiple teams are also important. As a postdoctoral researcher on our team, you will have the opportunity to use advanced proteomics and unique chemical probes to study the Haspin interactome and its function in different stages of the cell cycle. You will also investigate the role of Haspin in plasticity regulation and cell fate decision making, and evaluate its potential as a therapeutic target. If you are interested in this opportunity, please send your CV, cover letter, and contact information for at least three referees to Karel Souček at ksoucek@ibp.cz. We welcome all applicants who are interested in joining our team and embarking on an exciting research journey with us.
No applications were sent to our contact or e-mail address. Therefore, we continued the advertisement (see 2.15)
Indicator(s)/Targets: Recruitment of postdoc to the Department of Prof. J. Vondráček has high priority for both institutional strategy and HRS4R.
Current status: In Progress

Sub-Action 2.14
Title: New  PhD position (First Stage Researcher, R1) in the field of biology for the project "Disposition, distribution, and processing of DNA lesions in the genome of Arabidopsis thaliana plants defective in DNA repair and nucleosome assembly" (GAČR, 23-06643S)
Timing: Starting Date: August 1, 2023, deadline: July 25, 2023
Detailed description: Position is offered by the Department of Cell Biology and Radiobiology for the project "Disposition, distribution, and processing of DNA lesions in the genome of Arabidopsis thaliana plants defective in DNA repair and nucleosome assembly". Requirements: Education Level - Master Degree or equivallent, excellent knowledge of English, 1) Experience in the field of molecular biology and plant cytogenetics methods (nucleic acid extraction, preparation of chromosome preparations, FISH), 2) Experience in bioinformatics (active knowledge of Linux and programming in Python).
     After a thorough study of the qualifications of the applicants (arranged alphabetically by last name – Asgari, Gautam, Machelová) and on the basis of expert consultation with the researcher of the GAČR project, 23-06643S, "Disposition, occurrence and processing of DNA lesions in the genome of Arabidopsis thaliana plants defective for repair DNA and the assembly of nucleosomes" (Mgr. Vratislav Peška, Ph.D.) the selection committee instructed by Ing. Robin Ulrich on HRAW recruitment rules recommended to the director of the BFÚ of the Academy of Sciences of the Czech Republic to accept as a doctoral student in the DCBR department Mgr. Adéla Machelová.
Indicator(s)/Targets: Recruitment of PhD student to the Department of Cell Biology and Radiobiology. Action 2.14 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.15
Title: New postdoc position in cell biology for a project aimed at investigating the function of Haspin kinase and its role in the regulation of cell cycle, plasticity, and fate.
Timing: Starting Date: September 1, 2023, deadline August 31, 2023
Detailed description: Are you a recent PhD graduate in molecular and cell biology, biochemistry, or biophysics looking for an exciting postdoctoral opportunity? Join our team for a project aimed at investigating the function of Haspin kinase and its role in the regulation of cell cycle, plasticity, and fate. We are seeking a highly motivated and enthusiastic candidate with a PhD in the relevant fields. Prior postdoctoral experience is not required; we welcome candidates who are eager to learn and have a strong passion for research. Good communication skills and the ability to collaborate with multiple teams are also important. As a postdoctoral researcher on our team, you will have the opportunity to use advanced proteomics and unique chemical probes to study the Haspin interactome and its function in different stages of the cell cycle. You will also investigate the role of Haspin in plasticity regulation and cell fate decision making, and evaluate its potential as a therapeutic target. If you are interested in this opportunity, please send your CV, cover letter, and contact information for at least three referees to Karel Souček at ksoucek@ibp.cz. We welcome all applicants who are interested in joining our team and embarking on an exciting research journey with us.
Indicator(s)/Targets: Recruitment of postdoc to the Department of Prof. J. Vondráček has high priority for both institutional strategy and HRS4R.
Current status: In Progress

Sub-Action 2.16
Title: New PhD position in biology/chemistry
Timing: starting date September 1, 2023, deadline  August 30, 2023 23:59 h
Detailed description: PhD student (R1), part-time with 0.5 workload – 20 h/week at the Department of Biophysical Chemistry and Molecular Oncology for the project 21-46325L (Czech Science Foundation) - Development of a sensitive and selective electrochemical genosensor for on-site detection of Citrus Bark Cracking Viroid (CBCVd). Minimum educational attainment: Master’s degree, Qualification level: R1
Professional requirements: completed master's degree in molecular biology or biochemistry;knowledge of methods of molecular biology, biochemistry;experience in biophysical and electrochemical methods. Language requirements: English, level B2 or higher. Employee benefits: 25 days annual leave + 3 sick days; flexible working hours;possibility of partial remote work; vocational and language courses; up to CZK 8,000 per year for recreation, sports activities or culture; company catering at a reduced price; vitamin supplements, free drinking water/fluids; sports and cultural teambuilding events. Applications for the selection procedure, including CV should be sent electronically to hermanova@ibp.cz and ulrich@ibp.cz or by post to Královopolská 2590/135, 612 00 Brno, Czech Republic, with the visible indication ‘Selection Procedure + Specific Job Title’ on the envelope.
    After a thorough study of the qualifications of the applicants (Adil Mushtaq, Amna Khan, Arslan William, Hafiz Amir Nadeem, Hanan abdul KareeM, Kely Saad, Manika P Sharma, Marcela Hrušková, Muhammad Shahbaz, Tayyaba Mehmood, Negar Asgari, Saba Shakoor, Nandita Tiwari, Hana Sabi, Bottu Kavya Sree) and based on expert consultation with the project manager GAČR, 21-46325L, "Development of a sensitive and selective electrochemical genosensor for field detection of citrus bark cracking viroid" (CBCVBd) (doc. RNDr. Miroslav Fojta, CSc .) the selection committee (instructed by Ing. Robin Ulrich on HRAW recruitment rules) recommended to the director of the IBP CAS to accept as a doctoral student in the DBCMO department Mgr. Marcela Hrušková.
Indicator(s)/Targets: Recruitment of PhD student to the Department of Biophysical Chemistry and Molecular Oncology. Starting date: September 1, 2023. Action 2.16 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.17
Title: New PhD position in biology/chemistry
Timing: starting date October 1, 2023, deadline  September 25, 2023 23:59 h
Detailed description: PhD student (R1), 1.0 workload – 40 h/week at the Department of Structure and Dynamics of Nucleic Acids, project 23-05639S (Czech Science Foundation) - Molecular dynamics simulations of RNA: from static structures to molecular ensembles. Minimum educational attainment: Master’s degree, Qualification level: R1
Professional requirements: Excellent and recent knowledge of computational chemistry of nucleic acids, especially of atomistic simulations in explicit solvent; Active PhD study in the programme of biomolecular chemistry, biochemistry, biophysics or the related subjects; at any universities in Brno; Excellent knowledge of structure of protein-RNA complexes; Active knowledge of English language and ability to write scientific texts. Language requirements: English - minimal level C1. Applications for the selection procedure, including CV and cover letter should be sent electronically to krepl@ibp.cz and ulrich@ibp.cz or by post to Královopolská 2590/135, 612 00 Brno, Czech Republic, with the visible indication ‘Selection Procedure + Specific Job Title’ on the envelope.
    After a thorough study of the qualifications of the applicants (Abhimanyu Roy, Ahmad Hafezi, Amin Arjmandfard, Amina Marzeena S., Behnaz Mirzaei Behbahani, Hilal Çavuş, Mohammad Amin Bakhshan, Muhammad Naeem Ashraf, Negar Asgari, S. Suresh Kumar, Shaik Abdul Azeez A., Soodabeh Abbasi Sani, Toon Lemmens, Visvesvarar P.) and on the basis of expert consultation with the project manager GAČR, 23-05639S, "RNA molecular simulations: from static structures to molecular ensembles" (prof. RNDr. Jiří Šponer, DrSc.) the commission instructed by Ing. Robin Ulrich on HRAW recruitment rules recommended the director of the IBP CAS to accept as a Ph.D. student  in DSDNA department Toon Lemmens.
Indicator(s)/Targets: Recruitment of PhD student to the Department of Structure and Dynamics of Nucleic Acids. Starting date: October 1, 2023. Action 2.17 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.18
Title: New doctoral student in molecular biophysics and pharmacology
Timing: starting date November 1, 2023, deadline  October 5, 2023 23:59 h
Detailed description: Doctoral student (R1), 0.1 workload at the Department of Molecular Biophyics and Pharmacology, Minimum educational attainment: Master’s degree, Qualification level: R1
Professional requirements:graduated from the Master's studies of the Faculty of Science, majoring in biochemistry; doctoral student, majoring in biochemistry; knowledge needed to solve the issue of antitumor effectiveness of metallopharmaceuticals.  Language requirements: Active knowledge of English language. Applications for the selection procedure, including CV, cover letter and references should be sent electronically to Prof. RNDr. Viktor Brabec, DrSc. (head of the Department of Molecular Biophysics and Pharmacology, brabec@ibp.cz) and Ing. Robert Ulrich (head of the economic and personnel department, ulrich@ibp.cz) or by post to Královopolská 2590/135, 612 00 Brno, Czech Republic, with the visible indication ‘Selection Procedure + Specific Job Title’ on the envelope.
    After a thorough study of the qualifications of the applicants (Hossein Marofi, Kanad Roy, Sofia Sharkawy) and on the basis of expert consultation with the head of the Department of Molecular Biophysics and Pharmacology (Prof. RNDr. Viktor Brabec, DrSc.), the selection committee (instructed by Ing. Robin Ulrich on HRAW recruitment rules) recommended the director of the BFÚ of the Academy of Sciences of the Czech Republic to accept as a PhD student in the DMBP department Sofia Sharkawa.
Indicator(s)/Targets: Recruitment of doctoral student to the Department of Molecular Biophysics and Pharmacology. Starting date: November 1, 2023. Action 2.18 has high priority for both institutional strategy and HRS4R.
Current status: Completed

Sub-Action 2.19
Title: Postdoctoral fellow - bioinformatician
Timing: starting date January 1, 2024, deadline  November 27, 2023 23:59 h
Detailed description: Postdoctoral fellow (R1), 0.3-0.5 workload at the Department of Cell Biology and Radiobiology, Minimum educational attainment: Ph.D. in Genomics and Proteomics or a similar DSP (defended Ph.D. thesis) obtained in the last 4 years. Professional requirements: Knowledge of molecular biology and genomics with a focus on bioinformatic analysis of genomic and transcriptomic data; practice in the field of processing genomic and transcriptomic data evidenced by publication activity in quality international journals; a high degree of independence in solving research tasks and prerequisites for teamwork. Language requirements: Ability to actively communicate in English and Czech (necessary for communication with undergraduate students and their guidance). Employee benefits: 25 days annual leave + 3 sick days; flexible working hours; possibility of remote work; vocational and language courses; up to CZK 8,000 per year for recreation, sports activities or culture; company catering at a reduced price; vitamin supplements, free drinking water/fluids; sports and cultural teambuilding events. Applications for the selection procedure, including CV, cover letter and referencesshould be sent electronically to vpeska@ibp.cz and ulrich@ibp.cz or by post to Královopolská 2590/135, 612 00 Brno, Czech Republic, with the visible indication ‘Selection Procedure + Specific Job Title’ on the envelope.
Indicator(s)/Targets: Recruitment of postdoc fellow to the Department of Cell Biology and Radiobiology. Starting date: January 1, 2024. Action 2.19 has high priority for both institutional strategy and HRS4R.
Current status: In Progress

Sub-Action 2.20
Title: Postdoctoral fellow - Telomere biology of Trypanosomatids, DNA lesions in the genome of Arabidopsis thaliana defective in DNA repair and nucleosome assembly
Timing: starting date January 1, 2024, deadline  November 27, 2023 23:59 h
Detailed description: Postdoctoral fellow (R1), full time workload at the Department of Cell Biology and Radiobiology, Minimum educational attainment: Ph.D. in Genomics and Proteomics or a similar DSP (defended Ph.D. thesis) obtained in the last 4 years. Professional requirements: Knowledge of molecular biology and biochemistry methods. Experience with telomere analysis methods and telomerase activity; research experience evidenced by a list of publications in quality international journals; publications relevant to the research issue are an advantage; a high degree of independence in solving research tasks and prerequisites for teamwork. Language requirements: Ability to actively communicate in English and Czech (necessary for communication with undergraduate students and their guidance). Employee benefits: 25 days annual leave + 3 sick days; flexible working hours; possibility of remote work; vocational and language courses; up to CZK 8,000 per year for recreation, sports activities or culture; company catering at a reduced price; vitamin supplements, free drinking water/fluids; sports and cultural teambuilding events.
Indicator(s)/Targets: Recruitment of postdoc fellow to the Department of Cell Biology and Radiobiology. Starting date: January 1, 2024. Action 2.20 has high priority for both institutional strategy and HRS4R.
Current status: In Progress

Report for 2022-2023
Title: Report on the recruitment of scientists and PhD students to the Institute (activities in 2022-2023)
Detailed informationIn: In 2022, we have advertised and subsequently selected 8 candidates to various positions from Ph.D. positions (3 candidates – Vlastimil Tichý, Anoop Kumar Yadev, Jan Mašek), postdoc position (4 candidates – Filip Křikava, Eva Krivaková, Magdalena Skalníková, Batcho Adoosa Anicet) and to the postition of the director of the Institute (1 candidate – Eva Bártová).
In 2023, we advertised 12 positions (PhD and postdocs) and selected so far 9 candidates (Marine Serrano, Anna Korytářová, Jiří Rudolf, Adela Machelova and Marcela Hruskova for postdoc positions and Simran Negi, Jana Vepřek, Toon Lemmense and Sofi Sharkawy for PhD positions). Marine Serrano after a short time went away for family problems, therefore the advertisement is repeated. Jana Vepřek was selected but finally did not agree with the conditions of work. 
The number of applications was in average 11 with limits 0-104 candidates. In order to fulfill the OTM-R principles, the advertisements were published at the Institute web pages as well as Euraxess, with detailed description of the position (the field of work, period, required experience, knowledge of languages, salary and other conditions). In the advertisements the required documents were also listed. After the application deadline the candidates were carefully screened for the criteria of the position. The selection committee was instructed by Ing. Robin Ulrich on HRAW recruitment rules and made an unbiased and non-prioritized assessment of the academic qualifications and experience with respect to the research area, technical skills, and other requirements. Subsequently, the selected applicants were invited to the interviews with presentations, they also received detailed information about the offered position. The winning candidates were selected exclusively on the merit (experience and good laboratory skills in relation to the future research).
The selection of the director of the Institute is regulated by the academic rules (selection committee is nominated by the Council of the Academy of Sciences). The requirements as well as the procedure has been discribed at the web pages of the Institute, Academy of Sciences, at Euraxess and in Czech newspaper.
A new internal regulation on the recruitment and selection of researchers of the Institute of Biophysics of the CAS has been approved by ISAB and adopted in September 16, 2022. The basic OTM-R principles are involved in this document and the future recruitments will be realized according to this regulation. The regulation can be seen here.
Timing:  year 2022-2023
Responsible Unit: HR Award Group, HR Award Team (SC), Director of the Institute
Responsible Sub-Group: Stanislav Kozubek, Miroslav Krepl, Olga Nováková, Daniel Renčiuk
Indicator(s)/Targets: The number of recruitments (13) as well as the spectrum of positions (R1-R4) has been approximatelly fulfilled. R1/R2/R3/R4 was 5/7/0/1, which corresponds to the expected percentages (40/30/20/10). Measurable indicator (the number of recruited scientists/the number of scientists needed) has been fulfilled to 90%. The OTM-R principles were respected (see the detailed description) and substantially improved during the year. The communication tools used involved presentations in the Institute as well as interviews throught on-line tools (Zoom or other platforms). There are, however, some differences among departments. Action 2. had high priority for both institutional strategy and HRS4R. 
Current Status for 2022-2023: Completed.
Status of the Action: Completed. We will keep the best approach to OTM-R principles according to the regulation adopted and ensure they are embeded in all departments of the Institute.

Action 3. (text from the Initial phase)
Title: Translation of all internal rules into English. 
GAP Principles: 1, 4, 15
Timing: Implementation will be realized during the period 2021-2022 (the last quarter 2022 is the deadline). All rules and HR-related documents will be translated into English
Responsible Unit: HR Award Team, Director
Indicator(s)/Targets: Within 2 years of implementation, all institutional regulations and rules will be translated into English.
This activity will address all categories R1-R4 equally. Translated documents will be published on the IBP web page for HRS4R activities. Measurable indicator: number of documents translated/total number of documents. High priority for HRS4R.
Current Status: Completed

Sub-Action 3.1 (text from the Action Plan)
Title: Translation of the Gender Equality Plan into English. Translated document is published on the IBP web page.
Timing: 21 March, 2022
Responsible Unit: HR Award Team, Director
Indicator(s)/Targets: Elaboration of the Gender Equality Plan contributes to substantially to HR Award, however, it stand also separately as an important milestone of the Institute. High priority for HRS4R.
Current Status for this document: Completed

Sub-Action 3.2
Title: Translation of the improved History of IBP. Translated document on the History of IBP is here. https://www.ibp.cz/en/about-ibp/basic-information/history-of-the-ibp
Timing: 28 March, 2022
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: Translation of the document on the History of IBP contributes to better understanding the evolution of science and research tradition at the Institute.
Current Status for this document: Completed

Sub-Action 3.3
Title: Translation of the Internal regulation on the Recruitment and Selection of Researchers of the Institute of Biophysics of the CAS. Translated document on the Recruitment and Selection of Researchers of the Institute of Biophysics of the CAS is here.
Timing: May 30, 2022
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: Translation of the document on "Recruitment and Selection of Researchers" represents an important step towards internationalization of the recruitment process at the Institute. High priority for HRS4R.
Current Status for this document: Completed

Sub-Action 3.4
Title: Translation of the Internal regulation on the Establishment of the Elánek children's group. Translated document is here.
Timing:  January 1, 2022
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: Translation of the document on "Establishement of the children's group" will be important for foreign employees with children.  High priority for HRS4R.
Current Status for this document: Completed

Sub-Action 3.5
Title: Translation of the Internal regulation on "Internal Support of Mobility Program" (at our internal web page).
Timing:  October 30, 2022
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: Translation of the document on "Internal Support of Mobility Program" will be important for foreign employees to arrange their stays abroad. This regulation has high priority for both institutional strategy and for HRS4R.
Current Status for this document: Completed

Report for 2022
Title: Report on the translation of the HRAW related internal regulations and basic documents of the Institute into English
Detailed information: Basic regulations of the Institute as well as regulations important for foreing visitors such as "Organisational rules", "Career code", "Operating rules of the hostel and relaxation room", "Ethical codex" or  "Internal regulations on the recruitment and selection of researchers at the Institute of Biophysics of the Academy of Sciences of the Czech Republic, v. v. i." has been translated into English. All documents related to HRAW are systematically translated, too. Some less important documents related to specific activities (e.g. in relation to the central academic office) remain in Czech language only. 
Timing:  November 12, 2022
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: Translation of all documents and regulations related to HRAW as well as translation of basic regulations of the Institute in English has been completed. 100% of basic and HR-related documents have been translated into English. The remaining documents (approximately 30% remained in the Czech language). This step has high priority for both institutional strategy and for HRS4R.
Current Status for this document: Completed for 2022

Sub-Action 3.6
Title: Translation of the "Crisis Management Plan of the Institute of Biophysics" (at our internal web page).
Timing:  February 20, 2023
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: Translation of the document on Crisis Management Plan will be important for foreign employees to know the procedures, rights and obligations of the emloyees of the Institute in the event that the "state of crisis" is declared by the director. This regulation has high priority for both institutional strategy and for HRS4R.
Current Status for this document: Completed

Sub-Action 3.7
Title: Translation of the "Internal regulations on increasing institutional resilience at the IBP" (at our internal web page).
Timing:  February 20, 2023
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: Translation of the document on Internal regulations on increasing institutional resilience at the IBP will be important for foreign employees to know the measures to maintenain a high degree of institutional resilience at the Institute. This regulation has high priority for both institutional strategy and for HRS4R.
Current Status for this document: Completed

Report for 2022-2023
Title: Report on the translation of the HRAW related internal regulations and basic documents of the Institute into English
Detailed information: In 2022, basic regulations of the Institute as well as regulations important for foreing visitors such as "Organisational rules", "Career code", "Operating rules of the hostel and relaxation room", "Ethical codex" or  "Internal regulations on the recruitment and selection of researchers at the Institute of Biophysics of the Academy of Sciences of the Czech Republic, v. v. i." has been translated into English. In 2023 we have translated "Crisis Management Plan of the Institute of Biophysics" and "Internal regulations on increasing institutional resilience at the IBP" (enclosed). All documents related to HRAW are systematically translated, too. Some less important documents related to specific activities (e.g. in relation to the central academic office) remain in Czech language only.
Timing:  November 12, 2023
Responsible Unit: HR Working Group, HR Award Team (SC), Director of the Institute
Responsible Sub-Group: Stanislav Kozubek, Soňa Legartová, Klára Bednářová, Zuzana Machálková
Indicator(s)/Targets: Translation of all documents and regulations related to HRAW as well as translation of basic regulations of the Institute in English has been completed. 100% of new documents has been translated into English. Measurable indicator: the remaining documents (approximately 30% remained in the Czech language) are of minor importance for foreign employees. This step has high priority for HRS4R.
Current Status for this action: Completed.

Action 4. (text from the Action Plan)
Title: Evaluation of departments (bibliometric analyses of scientific results). Evaluation of departments and their leader is performed using two independent systems.
GAP Principles: 4, 10, 11, 15, 23
Timing: Improvement of science evaluation, implementation in 2021, and 2022 (the last quarter of 2022 is the deadline). Bibliometric evaluation of departments will occur at the end of each year; evaluation by International Scientific Advisory Board (ISAB will be performed biannually. According to the results of the evaluation, provided by management, and every 2nd year by ISAB, the budget for the departments will be modified.
Responsible Unit: HR Award Team and Deputy Director
Indicator(s)/Targets: Measurable indicators: number of outputs for each team divided into quartiles according to journal quality (and by the number of citations), comparison to EU and world standard. Support of individul teams by ISAB evaluation in terms of "increase support of the team", "continue support of the team", "there are problems (suggestions to solve them). Action 4. has high priority for institutional strategy average priority for and HRS4R. 
     Evaluation of departments and their leaders is performed using two independent systems. One is based on scientometry and the other is based on peer-review performed by the ISAB. Individual researchers of all categories are evaluated regularly using panels consisting of both internal and external experts. All these procedures are mostly transparent (accessible to all scientists of the Institute). During the on-site visit, ISAB evaluates all teams according to their publications, presentations and visits to their workplaces. ISAB provides independent evaluation/appraisal of all departments and their leaders and nomination of the best PhD students for the ISAB-president award. Members of ISAB provide recommendations of the best outputs for national evaluation. Internal evaluation by means of scientometry is performed each year using a 5-year period window. This evaluation procedure is organized by the Academy of Sciences of the Czech Republic. All outputs of the Institute are categorized using journal quality (journals are divided into quartiles and top decile according to the Article Influence Score). In addition, citations are also taken into consideration in a similar way (quartiles and top decile are calculated for each year, the field of science, and type of publication). These analyses are enclosed with the materials submitted to ISAB for consideration.Also, an independent evaluation is performed by the Academy of Sciences of the Czech Republic in the 5-year interval. Indicators: ISAB meeting documents, evaluation protocols. All categories R1-R4 will be acquainted with the results of the evaluation procedure.
Current Status: In progress
Remarks: In progress

Sub-Action 4.1
Title: Implementation of the national evaluation (bibliometry)
Timing: Evaluation has been performed for years 2016-2019 and finished at the end of 2021
GAP Principles: 4, 10, 11, 15, 23
Responsible Unit: Collegium of the Director
Indicator(s)/Targets: Measurable indicators: comparison to EU and world standard - in all main FORD fields of the Institute the production of outputs in the top decile and top quartile is higher or at the level of EU15 and substantially higher as compared with national levels. Based on these results, the final decision was that the Institute is among the best research organizations in the Czech Academy of Science (category A). Action 4.1 has high priority for institutional strategy average priority for HRS4R. 
Current Status: Completed
Remarks: The basic results and experience from the national evaluation have been presented at the Conference on the implementation of the national evaluation M17+ in Brno held on 30 March, 2022. The national evaluation will continue in 2022.

Sub-Action 4.2
Title: Bibliometric evaluation of departments (see here)
Detailed description: Departments of the Institute have been evaluated using bibliometric standard indicators introduced by the Czech Academy of Sciences as well as by the M17+ methodology of our national evaluation. This evaluation is performed in the intermediate time between regular evaluations (using both bibliometry and peer review methods). The results of evalution can influence the strategic decisions of the management of the Institute; in addition, financial improvements can be performed.
Timing: Bibliometric evaluation has been performed on August 8, 2022 for years 2017-2021(2020 in the case of citations)
GAP Principles: 4, 10, 11, 15, 23
Responsible Unit: Collegium of the Director
Indicator(s)/Targets: Measurable indicators: departments of the Institute are evaluated form the point of view of the number of publication and their quality (AIS deciles and quartiles of journals and the number of citations with the respect of the field of science, type of publication and year). The results of evaluation will be used by the management of the Institute for strategic purposes as well as for finacial adjustments. Action 4.2 has high priority for institutional strategy average priority for HRS4R. 
Current Status: Completed
Remarks: The selection of the appropriate indicators has been performed by the Academy of Sciences and the same indicators are use in national evaluation. Their justification can be found at https://www.vyzkum.cz/FrontClanek.aspx?idsekce=695512. 

Sub-Action 4.3
Title: ISAB meeting (see Program)
Meeting program:   Introductory prezentation by the director of the Institute, Eva Bártová (see picture). Main points of the program: 1) The ISAB statement for OP-JAC project – how to make the project attractive, and we need a short recommendation. 2) Selection of 2 of the best young scientists (students) awarded by the ISAB - the ISAB Award, 3) ISAB opinion if we should publish in MDPI journals, 4) A motivation tool for department leaders how to recruit young scientists with the potential to apply for, e.g., Junior Star and Lumina Queruntur projects (200 000 Euro/year for 4-5 years – to build new teams), 5) Recommendation of prof. Mergny for a new contract that will also be discussed by the Institutional Council – how to continue in cooperation. See meetings (here).
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: October 6, 2022
Responsible unit: Steering Commitee, Council of the Institute, Director of the Institute
Indicator(s)/Targets: This meeting program involved mainly prezentations of young scientists: Vojtěch Novohradský, Soňa Legartová, Petr Fajkus, Monika Hermanová, Radka Vozárová, Ondřej Vacek, Miroslav Krepl, Viktor Tokan, Jan Víteček and Tereza Pavlícová.  All young scientists prezented their research results and directions. Measurable indicator: 100%. Action 4.3 had high priority for both institutional strategy and for HRS4R. ISAB will decide about the quality of prezentations and speakers.
Number of participants form the Institute: 
Current status: Completed.

Report for 2022
Title: Report on the evaluation of departments using bibliometric analyses of scientific results
Detailed information: The evaluation of departments using bibliometry is performed between biannual evaluation by ISAB (see Action 4.2). In addition, national evaluation of the whole Institute has been performer with very good results (category A). Owing to ballanced results of the bibliometric evaluation, and in agreement with ARRA (Agreement on Reforming Research Assessment), we postponed the possible budget adjustments to the next year when ISAB evaluation will be performer. This year, ISAB evaluated young scientists and students (see Actions 5.1, 13.1 and 13.2). However, a number of prizes (for the best publication, for collaboration between depertments, for best application etc, will be awarded).  
Timing:  2022
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: Measurable indicators: number of outputs for each team divided into quartiles according to journal quality, comparison to EU and world standard. The results see in Action 4.1. and 4.2. This step has high priority for both institutional strategy and for HRS4R.
Current Status for this document: Completed for 2022

Sub-Action 4.4
Title: Bibliometric evaluation of departments (see histogram here)
Detailed description: Departments of the Institute have been evaluated using bibliometric method (sums of IF of journals published in 2022 were divided by FTE on 31.12.2022). This evaluation is performed for orientation on the request of the director. The results of evalution are discussed by the Council and recommendations can be given for strategic decisions of the management of the Institute or indifivual departments. Financial support for particular improvements can be added.
Timing: Bibliometric evaluation has been performed on January 27, 2023 for year 2022.
GAP Principles: 4, 10, 11, 15, 23
Responsible Unit: Council of the Institute, Director of the Institute
Indicator(s)/Targets: Measurable indicators: departments of the Institute are evaluated by a very simple method. The results of evaluation are discussed by the Council and can be used by the management of the Institute for strategic purposes as well as for finacial adjustments. Action 4.4 has high priority for institutional strategy average priority for HRS4R. 
Current Status: Completed
Remarks:  

Report for 2022-2023
Title: Report on the evaluation of departments using bibliometric analyses of scientific results and peer-review evaluation (ISAB and M17+ methodology of national evaluation)
Detailed information: The evaluation of departments and the Institute using bibliometry is performed each year using both own method (see Sub-Action 4.4), using outputs provided by the Czech Academy of Sciences (ASEP system, see Sub-Action 4.2) and using bibliometric part of the M17+ methodology of the national evaluation (see. Sub-Action 4.1). These results are used to check the performance of individual departments as well as the performance of the Institute. In addition, each year national evaluation is performed, in which the Institute is in the latest years marked "A" (the best ranking). Owing to the fact, that there are no pronounced problems in our departments or in the Institute and in agreement with ARRA (Agreement on Reforming Research Assessment), we postponed the possible budget adjustments to more complex evaluation by the CAS or recommendations by ISAB. The last year, ISAB evaluated young scientists and students (see Actions 5.1, 13.1 and 13.2). Therefore, we decided to organize the next ISAB meeting in 2024. A number of prizes (for the best publication, for collaboration between depertments, for best application etc, have been awarded).  
Timing:  2022-2023
Responsible Unit: HR Working Group, HR Award Team, Director of the Institute
Responsible Sub-Group: Stanislav Kozubek, Robert Ulrich, Milan Číž, Gabriela Ambrožová
Indicator(s)/Targets: Measurable indicators: number of outputs for each team divided into quartiles according to journal quality, comparison to EU and world standards. The results see in Action 4.1. and 4.2. This step has high priority for both institutional strategy and for HRS4R.
Current Status for this document: Completed for 2022-2023.
Status: Owing to new documents accepted by the EU (ARRA), the action will continue in the next period 2024-2026 with focus to ARRA.

Action 5. (text from the Action Plan)
Title: The best PhD student award, Application Award, Internal cooperation Award, Methodology Award, and The scientific paper of the year.
GAP Principles: 4, 8, 11, 15, 16
Timing: According to the recommendation of the supervisor and based on the evaluation of the Director's Collegium, the above mentioned awards will be implemented and the winning scientists will be awarded (at the end of each year). Director may also select the paper of the year with the highest contribution of IBP-employees (own "know-how"). These employees will be awarded a financial bonus (also at the end of each year). 
Responsible Unit: HR Award Team Advisory board (Collegium of the Director), Head of the Institutional Council
Indicator(s)/Targets: Indicators: diploma and financial bonus for Awards. Awards in all categories will be selected by WG.
These awards are open for all categories R1-R4 that have a chance to be annually awarded. Measurable indicators: % of awarded scientist from the maximum available.  Action 5. has high priority for both institutional strategy and HRS4R. 
Current Status: In progress
Remarks:

Sub-Action 5.1
Title: Awards for the best postdoc research results (evaluated by the ISAB, see here and here)
Detailed Information: Awards for the best postdoc research resluts obtained Petr Fajkus and Miroslav Krepl. Petr Fajkus studied evolution of plant telomerase RNAs. Mirosla Krepl used molecular dynamics and NMR spectroscopy for the determination of the role of hydration in recognition of N6-methyladenosine by the YTHDC1 YTH domain. The prize for the best prezentation of the Ph.D. student obtained Radky Vozárová (see 13.2). See Meetings (here).
Timing: The results were prezented at the ISAB meeting on October 6, 2022
Responsible Unit: ISAB, HR Award Team Advisory board (Collegium of the Director), Head of the Institutional Council
Indicator(s)/Targets: Diploma and financial bonus for Awards. Awards have been selected by the ISAB.
These awards are open for all categories R1-R4 that have a chance to be annually awarded. Measurable indicators: 100%, the sub-Action has been fulfilled.  Action 5.1 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed
Remarks:

Sub-Action 5.2
Title: Awards for the best publications in 2022 obtained the team of authors from the Department of Molecular Biophysics and Pharmacology (here) and the team of authors form the Department of Plant Developmental Genetics (here)
Detailed Information: The prize awarded by the director of the Institute, Eva Bártová, obtained the authors: J. Malina, H. Kostrhunová, V. Novohradský, P. Scott, and V. Brabec for the paper "Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles", published in Nucleic Acid Research in 2022 and the authors: V. Bačovský, R. Čegan, E. Tihlaříková, V. Neděla, V. Hudzieczek, L. Smrža, T. Janíček, V. Beneš, and R. Hobza for the paper "Chemical genetics in Silene latifolia elucidate regulatory pathways involved in gynoecium development published in Journal of Exeprimental Botany.
Timing: November 25, 2022
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prizes have been awarded by the director of the Institute with diplomas and financial bonuses. The awards are open for all categories R1-R4 that have a chance to be annually awarded. The sub-Action has been fulfilled.  Action 5.2 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed

Sub-Action 5.3
Title: Award for young scientists in 2022 obtained V. Bačovský (see here)
Detailed Information: The prize for youg scientists awarded by the director of the Institute, Eva Bártová, obtained Václav Bačovský from the Department of Plant Developmental Genetics. The research results are involved in publications Bačovský et al, "Chemical genetics in Silene latifolia elucidate regulatory pathways involved in gynoecium development", Journal of Experimental Botany, 2022, vol. 73, p-2354-2367 and Bačovský et al., "The Sister Chromatid Division of the Heteromorphic Sex Chromosomes in Silene Species and Their Transmissibility towards the Mitosis" Interantional Journal of Molecular Sciences", 2022,vol. 23. article number 2422.
Timing: November 25, 2022
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prize has been awarded by the director of the Institute with diploma and financial bonus. The award is open for category R1 that have a chance to be annually awarded. Action 5.3 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed 

Sub-Action 5.4
Title: Award for the best application in 2022 obtained Roman Hobza (see here)
Detailed Information: The prize for the best application awarded by the director of the Institute, Eva Bártová, obtained Roman Hobza from the Department of Plant Developmental Genetics. The prize has been awarded for the establishment of an application laboratory for agricultural biotechnology.
Timing: November 25, 2022
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prize has been awarded by the director of the Institute with diploma and financial bonus. The award is open for category R1-R4 that have a chance to be annually awarded. Action 5.4 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed 

Sub-Action 5.5
Title: Award for internationalization in 2022 obtained the research group of E. Sýkorová (see here)
Detailed Information: The prize for youg scientists awarded by the director of the Institute, Eva Bártová, obtained the research group of Eva Sýkorová from the Department of Cell Biology and Radiobiology. The research was focused to plant telomerase and its interaction networks with multiprotein complexes.
Timing: November 25, 2022
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prize has been awarded by the director of the Institute with diploma and financial bonus. The award is open for category R1-R4 that have a chance to be annually awarded. Action 5.2 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed 

Sub-Action 5.6
Title: Cooperation Award in 2022 obtained the research collective: L Dobešová, T. Gier, O. Kopečná, E. Pagáčová, T. Vicar, F. Bestvater, J. Toufar, A. Bačíková, P. Kopel, R. Fedr, G. Hildenbrand, I. Falková, M. Falk and M. Hausmann (see here)
Detailed Information: The prize for youg scientists awarded by the director of the Institute, Eva Bártová, obtained the research collective: L Dobešová, T. Gier, O. Kopečná, E. Pagáčová, T. Vicar, F. Bestvater, J. Toufar, A. Bačíková, P. Kopel, R. Fedr, G. Hildenbrand, I. Falková, M. Falk and M. Hausmann for the research results on "Incorporation of Low Concentrations of Gold Nanoparticles: Complex Effects on Radiation Response and Fate of Cancer Cells. Pharmaceutics, 2022, 14(1). Using 3D confocal microscopy and super-resolution single molecule localization microscopy, the effect of gold nanoparticles on the repair of radiation induced DSB was investigated. The results are important for the development of more efficient and safe radiation therapy of tumours.
Timing: November 25, 2022
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prize has been awarded by the director of the Institute with diploma and financial bonus. The award is open for category R1-R4 that have a chance to be annually awarded. Action 5.2 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed 

Report for 2022
Title: Report on the prizes awarded by the director of the Institute, Eva Bártová, in 2022
Detailed information: In 2022, the following prizes have been awarded: Awards for the best postdoc research results (2 prizes), Awards for the best publications (2 prizes), Award for young scientists, Award for the best application, Award for internationalization, and Cooperation Award. These employees have also obtained financial bonuses. The prize for the best methodology have not been awarded.
Timing:  end of 2022
Responsible Unit: HR Award Team, Director of the Institute
Indicator(s)/Targets: These awards are open for all categories R1-R4 that have a chance to be annually awarded. Measurable indicator: number of awards from the maximum possible (4/5=80%). This step has high priority for both institutional strategy and for HRS4R.
Current Status for this document: Completed for 2022

Sub-Action 5.7
Title: Award for young scientists in 2023 obtained P. Pokorná, D. Dobrovodský, R. Vozárová a M. Černík (see here).
Detailed Information: The prize for youg scientists awarded by the director of the Institute, Eva Bártová, obtained Pavlina Pokorná (1st place), Daniel Dobrovodský (2-3rd place), Radka Kalfusová (2-3rd place) a Marek Černík (4th place).
Timing: November 14, 2023
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prizes have been awarded by the director of the Institute with diplomas and financial bonuses. The award is open for category R1 that have a chance to be annually awarded. Action 5.7 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed 

Sub-Action 5.8
Title: Awards for the best publication in 2023 obtained the team of authors from the Department of Biophysics of Nucleic Acids (Daniel Renciuk)
Detailed Information: The prize awarded by the director of the Institute, Eva Bártová, obtained Skolakova P., Palacky J., Subert D., Renciuk D., and Vorlickova M. These scientists published  the following publication: Skolakova P., Gajarsky M., Palacky J., Subert D., Renciuk D., Trantirek L., Mergny J.L.,Vorlickova M. DNA i-motif formation at neutral pH is driven by kinetic partitioning. Nucleic Acids Research, 2023, 51, 2950–2962.  The work is mainly the result of the Department of Biophysics of Nucleic Acids, BFÚ, and the IBP authors have only one affiliation (IBP CAS). The publication continues and explains the experimental results obtained in P. Školáková's previous work published in Nucleic Acids Research, 2019, 47, 2177-2189, which has currently 40 citations.
Timing: December 15, 2023
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prizes have been awarded by the director of the Institute with diplomas and financial bonuses. The awards are open for all categories R1-R4 that have a chance to be annually awarded. Action 5.8 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed

Sub-Action 5.9
Title: Award for the best application in 2023 obtained the team of authors from the Department of Plant Developmental Genetics (Roman Hobza)
Detailed Information: The prize including financial bonus for the best application awarded by the director of the Institute, Eva Bártová, obtained Roman Hobza from the Department of Plant Developmental Genetics. The prize has been awarded for cytogenetic analysis and editation of hop genome. The department works with the world's largest breweries and hop breeders to implement the molecular methods that the laboratory develops to improve the breeding process. This is the commercial cooperation of the Application Laboratory with individual entities on a contractual basis. Cytogenetic analysis of specific hop cultivars was one of the key steps for assembling hop genome sequences and thus brought fundamental insights into the differences between European and American wild hops. With the increasing popularity of using wild hops in breeding, this knowledge can significantly help in the breeding of new cultivars. Furthermore, thanks to the established methodology of plant genome editing in our laboratory, we will verify candidate genes important in the mechanism of sex determination and other agronomically significant characteristics of hops (resistance to biotic and abiotic stress, yield) for the Japanese company Suntory.
Timing: December 15, 2023
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prize has been awarded by the director of the Institute with diploma and financial bonus. The award is open for category R1-R4 that have a chance to be annually awarded. Action 5.9 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed  

Sub-Action 5.10
Title: Awards for the collaboration among departments of IBP CAS in 2023 obtained the team of authors from the Department of Biophysical Chemistry and Molecular Oncology (Miroslav Fojta)
Detailed Information: The prizes including financial bonuses awarded by the director of the Institute, Eva Bártová, obtained Dobrovodsky D., Danhel A., Renciuk D., and Fojta M. These scientists collaborated and created results for the following publication: Dobrovodsky, D., Danhel, A., Mothes-Martin, E., Pratviel G., Renciuk D., Mergny, J.-L., Fojta, M. Interfacial behaviour of oligonucleotides prone to G-quadruplex formation on negatively charged electrode surface monitored by electrochemical probes. Electrochim. Acta., 442(2023), 141878, This publication was created in cooperation with the Department of Biophysics of Nucleic Acids (Daniel Renciuk). In this work, a new concept of an electrochemical method for the study of DNA structure with a focus on DNA G-quadruplexes, based on the use of redox probes, was presented and applied. All the results obtained using this new electrochemical method were verified and supported by the CD spectroscopy method, which is a specialty of the department of Daniel Renciuk and at the same time the best reference method for studying these structures.

Timing: December 15, 2023
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prizes have been awarded by the director of the Institute with diplomas and financial bonuses. The awards are open for all categories R1-R4 that have a chance to be annually awarded. Action 5.10 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed

Sub-Action 5.11
Title: Awards for the best publication prepared in international collaboration in 2023 obtained the team of authors from the Department of Molecular Biophysics and Pharmacology (Viktor Brabec)
Detailed Information: The prizes including finacial bonuses awarded by the director of the Institute, Eva Bártová, obtained Novohradsky V., Markova L., Kostrhunova H., Kasparkova J., Brabec V. These scientists prepared in collaboration with foreign authors the following publication: Sarkar, A.; Novohradsky, V.; Maji, M.; Babu, T.; Markova, L.; Kostrhunova, H.; Kasparkova, J.; Gandin, V.; Brabec, V.; Gibson, D. Multitargeting prodrugs that release oxaliplatin, doxorubicin and gemcitabine are potent inhibitors of tumor growth and effective inducers of immunogenic cell death. Angewandte Chemie. International Edition, 2023, 62, e202310774.
    In 2023, the long-term collaboration of Viktor Brabec with the laboratory at the Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, focused on the development of multimodal cancer drugs derived from metal complexes, culminated. With the staff of this laboratory, Viktor Brabec already published 25 joint publications in renowned high-impact journals.The above work is the culmination of this collaboration, in which they described the first-ever example of a Pt(IV) prodrug simultaneously affecting multiple pharmacological targets, composed of three FDA-approved anticancer drugs linked by self-immolating linkers facilitating the release of the active forms of all drugs after their reduction activation inside cancer cells and which are designed to induce immunogenic cell death. It is a true "multitargeting" prodrug that combines the best properties of individual drugs and synergistically increases their antitumor effectiveness. Also of importance is the fact that this new prodrug was more effective than the three FDA drugs of which this prodrug is composed, also in vivo in two immunocompetent mouse tumor models. An important circumstance emphasizing the significant contribution of the laboratory from the IBP to this collaboration is also the fact that the first shared and shared corresponding author on this publication are authors with the exclusive affiliation of the IBP CAS and that half of the authors were from the IBP CAS with the exclusive affiliation of the IBP CAS.

Timing: December 15, 2023
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prizes have been awarded by the director of the Institute with diplomas and financial bonuses. The awards are open for all categories R1-R4 that have a chance to be annually awarded. Action 5.11 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed

Sub-Action 5.12
Title: Awards for the best methodology in 2023 obtained the authors from the  Department of Plant Developmental Genetics (Roman Hobza)
Detailed Information: The prizes including financial bonuses for the best methodolgy awarded by the director of the Institute, Eva Bártová, obtained Janicek T., Hobza R., and Hudzieczek V. These authors prepared the publication: Janíček T, Hobza R, Hudzieczek V. (2023) Laser Capture Microdissection: From Genomes to Chromosomes, from Complex Tissue to Single-Cell Analysis. Methods Mol Biol. 2023;2672:163-175. doi: 10.1007/978-1-0716-3226-0_9.
   Microdissection using a laser beam is a unique method for researching complex biological samples. Using a laser beam, it is possible to separate cells or chromosomes not only on the basis of morphology but also on the basis of the fluorescence signal. This innovative approach, which has been developed and optimized for a long time by the Department of Plant Developmental Genetics, currently enables the most precise selection of biological material and is therefore becoming indispensable for detailed analyzes at the level of (epi)genomes, transcriptomes or proteomes. Precise and targeted sequencing of nucleic acids in the context of complex tissues is coming to the fore of the scientific community, which is why our laboratory was approached to present a protocol for laser microdissection in the prestigious "Methods in Molecular Biology" series (Springer Protocols).
Timing: December 15, 2023
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prizes have been awarded by the director of the Institute with diplomas and financial bonuses. The awards are open for category R1-R4 that have a chance to be annually awarded. Action 5.12 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed 

Sub-Action 5.13
Title: Award for internationalization in 2023 obtained a Dr. Hana Polasek-Sedlackova from the Departments of Cell Biology and Epigenetics (Eva Bartova).
Detailed Information: The prize including financial bonus for internationalization awarded by the director of the Institute, Eva Bártová, obtained Dr. Hana Polasek-Sedlackova working on Junior Star project from ERA.
Timing: December 15, 2023
Responsible Unit: HR Award Team, Head of the Institutional Council, Director of the Institute
Indicator(s)/Targets:  The prize has been awarded by the director of the Institute with diploma and financial bonus. The award is open for category R1-R4 that have a chance to be annually awarded. Action 5.13 has high priority for both institutional strategy and HRS4R. 
Current Status: Completed 

Report for 2022-2023
Title: Report on the prizes awarded by the director of the Institute, Eva Bártová, in 2022-2023
Detailed information: In 2022, the following prizes have been awarded: Awards for the best postdoc research results (2 prizes), Awards for the best publications (2 prizes), Award for young scientists, Award for the best application, Award for internationalization, and Cooperation Award. The awarded employees have also obtained financial bonuses. The prize for the best methodology have not been awarded.
In 2023 the selection of prizes have been performed by means of more transpared approach - using the Collegium of the director. The suggested nominations have been evaluated by the Collegium and candidates have been suggested to the director for the corresponding category of prizes. The prizes have been awarded on December 15, 2023.
Timing:  2022, end of 2023
Responsible Unit: HR Award Working Group, HR Award Team, Collegium of the Director, Director of the Institute
Responsible Sub-Group: Eva Bártová, Martin Falk, Daniel Renčiuk, Gabriela Ambrožová
Indicator(s)/Targets: These awards are open for all categories R1-R4 that have a chance to be annually awarded. Measurable indicator: number of awards from the maximum possible (4/5=80% for 2022 and 100% for 2023). This step has high priority for both institutional strategy and for HRS4R.
Current Status for this document: The prizes for 2023 have been awarded on December 15, 2023.
Status: This activity will continue in the next period of HR Award implementation.We will improve the transparency of the selection; new types of the awards could be established.

Action 6. (text from the Action Plan)
Title: An improvement of attestation rules
GAP Principles: 11, 12, 21, 24, 26, 28, 30, 35, 36, 40
Timing: Regulation will be adapted at the last quarter of 2022, attestation will be performed continually per roll and on-site at the end of each year.
Responsible Unit: HR Award Team, Attestation Commission
Indicator(s)/Targets: The Attestation Commission works per roll or during the on-place meetings. Commission provides R1-R4 categorization, based on the suggestion of the department leaders. The minutes of the Attestation Commission will be translated into English. All categories R1-R4 will be evaluated by the Attestation Commission, all employee has a chance to discuss his/her position and salary with the Attestation Commission, held every year. All employees will be acquainted with the OTM-R document. A new possibility: an employee, who is not satisfied with their salary, can apply for a salary improvement and can defend their scientific quality before the Attestation Commission. Measurable indicator: number of cases with improved salaries/number of employees required the improvement. Action 6. has high priority for HRS4R, average priority for institutional strategy. 
Current Status: In progress
Remarks:

Sub-Action 6.1
Title: Improved positions of employees
Timing: January 25, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved for 2 employees: Patzák Josef and Coulon Rémi. All employees have been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.1 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.2
Title: Improved positions of employees
Timing: February 25, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to V4 (R3) for 4 employees: Kahounová Zuzana, Procházková Jiřina, Slabáková Eva and Suchánková Tereza. All employees have been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.2 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.3
Title: Improved positions of employees
Timing: March 1, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 4 employees: Mašek Jan, Batcho Agossa Anicet, Pešková Michaela, Zhang Zhengyue. All employees have been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.3 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.4
Title: Improved positions of employees
Timing: May 31, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 7 employees: Sochorová Jana, Volfová Polanská Eva, Štros Michal, Pala Jan, Cantara Alessio, Zhang Zhengyue, Jenner Leon Paul. All employees have been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.4 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.5
Title: Improved positions of employees
Timing: June 27, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 6 employees: Vazquez Gomez Gerardo, Bodláková Markéta, Porubiaková Otilia, Drotárová Magdaléna, Petr Marek, Vojsovič Matúš. They have been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.5 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.6
Title: Improved positions of employees
Timing: July 29, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 1 employee: Šislerová Lucie. She has been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.6 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.7
Title: Improved positions of employees
Timing: August 23, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 3 employee: Vazquez Gomez Gerardo, Skoroplyas Svitlana, Křikava Filip. Thy have been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.7 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.8
Title: Improved positions of employees
Timing: September 29, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 1 employee: Tichý Vlastimil. He has been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.8 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.9
Title: Improved positions of employees
Timing: October 31, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 1 employee: Tichý Vlastimil. He has been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.9 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.10
Title: Improved positions of employees
Timing: December 6-7, 2022
Responsible unit: Attestation Commission
Indicator(s)/Targets: Attestation commission sit in person on two days. In the first session, positions have been improved to 24 employees for the department of M. Falk, 18 employees of L. Kubala, 3 employees from the Animal Facility, 4 employees of E. Bártová, 3 employees from Scientific Incubator, 17 employees of M. Fojta and 7 employees of A. Kovařík. In the second session, positions have been improved to 5 employees of V. Brabec, 17 employees of R. Hobza6 employees of D. Renčiuk, 7 employees of J. Vondráček and 8 employees of J. Šponer. They have been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.10 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Report for 2022
Title: An improvement of attestation rules (the improved regulation can be seen here)
Detailed information: Positions have been improved for 33 employees during the per-roll attestations. Regulation has been adapted in 2022, attestation has been performed continually per roll in 2022 and on-site at the end of the year (December 6-7, 2022).
Timing: report for 2022.
Responsible Unit: HR Award Team, Attestation Commission
Indicator(s)/Targets:  Commission provided R1-R4 categorization, working hours and salaries, based on the suggestions of the department leaders.  All employees had a chance to discuss his/her position and salary with the Attestation Commission. All employees have been acquainted with the OTM-R document. An employee, who is not satisfied with his salary, can apply for a salary improvement and can defend his scientific quality before the Attestation Commission.The minutes of the Attestation Commission are stored together with the template for translation into English. Measurable indicator: number of cases with improved salaries/number of employees required the improvement (in 2022 there are no such cases). Action 6. has high priority for HRS4R, average priority for institutional strategy. 

Sub-Action 6.11
Title: Improved positions of employees
Timing: January 31-March 31, 2023
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 6 employees: Veverka Pavel (January 31, 2023), Vozárová Radky (February 27, 2023), Serrano Maciá Marina, Indu, Batcho Agossa Anicet (March 13, 2023) and Skoroplyas Svitlana (March 31, 2023). They have been acquainted with the OTM-R document.  The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.11 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.12
Title: Improved positions of employees
Timing: May 31, 2023
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 2 employees: Kuderová Alena and Yadav Anoop Kumar. These employees have been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.12 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.13
Title: Improved positions of employees
Timing: June 15, 2023
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 4 employees: Dobrovolná Michaela, Kratochvilová Libuše, Mergny Jean-Louis and Kumari Juhi. These employees have been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.13 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Sub-Action 6.14
Title: Improved positions of employees
Timing: June 29, 2023
Responsible unit: Attestation Commission
Indicator(s)/Targets: Positions have been improved to 1 employees: Pruchkouski Dymitry. These employe has been acquainted with the OTM-R document. The minutes of the Attestation Commission are stored together with the template for translation into English. Action 6.14 has high priority for both institutional strategy and HRS4R.
Current Status: Completed.

Report for 2022-2023
Title: An improvement of attestation rules (the improved regulation is enclosed "Career rules")
Detailed information: In 2022, positions have been improved for 33 employees during the per-roll attestations. Regulation has been adapted in 2022, attestation has been performed continually per roll in 2022 and on-site at the end of the year (December 6-7, 2022). In 2023, positions have been improved for 13 employees (up to Novemer, 2023) during the per-roll attestations. The on-site attestation will be performed at the end of the year.
Timing: report for 2022-November, 2023.
Responsible Unit: HR Award Team, Attestation Commission, Director of the Institute
Responsible Sub-Group: Eva Bártová, Martin Falk, Daniel Renčiuk, Miroslav Fojta
Indicator(s)/Targets:  Commission provided R1-R4 categorization, working hours and salaries, based on the suggestions of the department leaders and in agreement with the career rules.  All employees had a chance to discuss his/her position and salary with the Attestation Commission. All employees have been acquainted with the OTM-R document as well as with Career rules. An employee, who is not satisfied with his salary, can apply for a salary improvement and can defend his scientific quality before the Attestation Commission.The minutes of the Attestation Commission have standard form; the template is translated into English (the template as well as all minutes are stored). Measurable indicator: number of cases with improved salaries/number of employees required the improvement (in 2022-23 there are no such cases). This reflects the fact that the employees are not sufficiently aware of such possibility. Therefore, we will continue this activity in order to achieve better solution of this problem. Action 6. has high priority for HRS4R, average priority for institutional strategy. 
Current Status: Completed for 2022-2023, the continuation will involve consideration of possible changes of the Career rules in order to increase the self-confidence of the employees undergoing attestation to give to the management a feedback about the salaries and conditions of work in general.

Action 7. (text from the Action Plan)
Title: Social equality in gender, age, education, and citizenship via the social fund.
GAP Principles: 10, 19, 20, 27
Timing: We will eliminate gender imbalance; we will support equality of age, citizenship, social categories, etc. From this view, we will use the support from the social fund working on solidarity level. Chages will be introduced gradually; we will inform about them at the last quarter of the year.
Responsible Unit: HR Award Steering Commitee
Indicator(s)/Targets: Principles of equality are well implemented at the institute, but new benefits from the social funds will be established. For example, 3 days of sick days have been provided to employees. The kid's corner is working and our plan is to support social activity that will be available for all R1-R4 categories in 2021-2024. We will also apply to the Czech Academy of Sciences for a certificate called Emeritus employee; thus, we are going to support seniority. Via such activity, retired scientists have access to the workplace and can attend the library, scientific meetings, etc. Measurable indicator: number of employes with some benefit/total number of employes at given category (women, various social categories, atc). Action 7 has high priority for HRS4R.
Current Status: In progress
Remarks:

Sub-Action 7.1
Title: Gender Equality Plan. We have elaborated the plan to improve gender equality in different aspects of scientific life:
1. Reconciling employees' work and private lives
2. Gender balance in leadership and decision-making
3. Gender balance in recruitment and career advancement
4. Measures against gender-based behaviour incompatible with social standards.
Timing of the Sub - Action 7.1 is described in a separate document Gender Equality Plan (here).
Indicators/Targets of the Sub - Action 7.1 are described in the GEP.
Action 7.1 has high priority for HRS4R. 
Current Status: In progress

Sub-Action 7.2
Title: Research emeritus.
Director of the Institute, prof. Eva Bártová, suggested two former employees, prof. B. Vyskot and prof. A. Lojek for the title of "Research Emeritus". It was approved by the president of the Academy of Sciences. They can enjoy all the benefits associated with this and determined by the career rules (e.g. take part at all social activities of the Institute)
Timing: June 7, 2022
Indicators/Targets: In the category of possible former employees we achieved 100% effectiveness. Action 7.2 has high priority for HRS4R. 
Current Status: Completed

Sub-Action 7.3
Title: Medal for PR activities and medal for the merit of the Academy of Sciences.
Director of the Institute, prof. Eva Bártová, proposed two employees, Assoc. Prof. E. Kejnovský and Assoc. Prof. S. Kozubek to receive the medal for  PR activities and the medal for the merit of the Academy of Sciences. Both suggestions were approved by the president of the Academy of Sciences.
Timing: June 13, 2022
Indicators/Targets: In the category of possible employees we achieved 100% effectiveness. Action 7.3 has high priority for HRS4R. 
Current Status: Completed

Sub-Action 7.4
Title: Letter of thanks to Soňa Karásková (see the letter).
Director of the Institute, prof. Eva Bártová, suggested Soňa Karásková to the president of the Czech Academy of Sciences, prof. Eva Zažimalová, to receive a "Letter of thanks" for dedicated work for the benefit of the Institute. This suggestion has been approved by the Academy Council and the president of the Czech Academy of Sciences granted the "Letter of thanks" to Soňa Karásková
Timing: April 29, 2022
Indicators/Targets: In the category of possible employees we achieved 100% effectiveness. Action 7.4 has high priority for HRS4R. 
Current Status: Completed

Sub-Action 7.5
Title: Senior club
Director of the Institute, prof. Eva Bártová, suggested prof. Boris Vyskot to establish "Senior Club". The Club will involve scientists working earlier at the Institute 65+ years old. They will meet at least once a year to discuss scientific topics and points of view (both recent and earlier). So far, names and addresses have been collected.
Timing: July 1, 2022
Indicators/Targets: The "Senior Club" will involve employees of all categories (so far we have colected 27 colleagues). Action 7.5 has high priority for HRS4R. 
Current Status: In Progress

Sub-Action 7.6
Title: Meeting of senior empoyees of IBP with young scientists (pictures can be seen here).
Program: 1) director of the Institute, Eva Bártová, presented a lecture "History and present of the Institute", 2) discussion with Prof. Jiří Vácha about the life in the Institute. Director of the Institute, Eva Bártová, awarded previous directors (M. Bezděk and S. Kozubek) for the merit of the Institute.
Timing: November 3, 2022, at 13 h, auditorium of the Institute
Indicators/Targets: The meeting will contribute to the realization of the position of the Institute among other research organizations in the case of young scientists.  Action 7.6 has high priority for HRS4R. 
Number of participants: 25 seniors and 27 participants from IBP
Current Status: Completed

Report for 2022
Title: Report on the improvement of the social equality in gender, age, education, and citizenship in 2022
Detailed information: We have performed important steps to the elimination of the gender imbalance and to achieve equality of employees with different age, citizenship, social categories, etc. First of all, we have elaborated "Gender Equality Plan" (see 7.1) with a number of actions and already in 2022 a very successful lecture of Mgr. P. Špondrova on "Gender in Leadeship" was realized. In addition, we established the "Senior club" and organized "Meeting of senior employees with young scientists" (see 7.6). Several medals and other forms of prizes have been awarded to employees of the Institute (7.2-7.4). We have also applied to the Czech Academy of Sciences for the certificate called Emeritus employee for our employees (see 7.2); thus, we supported seniority. Via such activity, retired scientists have access to the workplace and can attend the library, scientific meetings, etc.
Timing: report for 2022.
Responsible Unit: HR Award Team, Attestation Commission, Director of the Institute
Indicator(s)/Targets:  Principles of equality have been improved and new benefits were established (using also social fund).  Our plan is to support social activity that will be available for all R1-R4 categories in 2021-2024. Measurable indicator: number of employes with some benefit/total number of employes at given category (women, various social categories, atc). We estimate this percentage to approximately 70%. Action 7 has high priority for HRS4R.

Sub-Action 7.7
Title: Research emeritus for Dr. J. Široký (see here)
Director of the Institute, prof. Eva Bártová, suggested former employee, dr. J. Široký for the title of "Research Emeritus". It was approved by the president of the Academy of Sciences. He can enjoy all the benefits associated with this and determined by the career rules (e.g. take part at all social activities of the Institute)
Timing: January 12, 2023
Indicators/Targets: In the category of possible former employees we achieved 100% effectiveness. Action 7.7 has high priority for HRS4R. 
Current Status: Completed

Sub-Action 7.8
Title: Garden party of empoyees of IBP (pictures can be seen here and here).
Program: Employees of the Institute worked in the garden and improved the environment for sports use (e.g. volleyball).
Timing: May 5, 2023, at 15 h
Indicators/Targets: The meeting contributed to team building and improving the environment of the Institute.  Action 7.8 has average priority for HRS4R. 
Number of participants: 27 participants from IBP
Current Status: Completed

Sub-Action 7.9
Title: Senior Day (pictures can be seen here).
Program: 1) 14-15 h Showing historical movies related to IBP CAS, 2) 15-15:45 h Concert of the group "DNA" 3) 15:45 refreshment, visits to laboratories
Timing: November 24, 2023, at 14 h, auditorium of the Institute
Indicators/Targets: Senior Day has contributed to the awareness of seniors working earlier at IBP about new directions of the Institute.  Action 7.9 has high priority for HRS4R. 
Number of participants: 41 seniors - earlier emploees of IBP
Current Status: Completed

Report for 2022-2023
Title: Report on the improvement of the social equality in gender, age, education, and citizenship in 2022-2023
Detailed information: We have performed important steps to the elimination of the gender imbalance and to achieve equality of employees with different age, citizenship, social categories, etc. First of all, we have elaborated "Gender Equality Plan" (see 7.1) with a number of actions and already in 2022 a very successful lecture of Mgr. P. Špondrova on "Gender in Leadeship" was realized. The lecture continued in 2023 again by Mgr. P. Špondrová on "Equality between men and women". This course was available for all categories of employees. The course was focused to gender stereotyps, their negative influence on women and men. Some potentially discriminate cases were discussed. The "Anti-discrimination law" has been discusses and some principles were explained. In addition, we established the "Senior club" and organized "Meeting of senior employees with young scientists" (see 7.6). Another meeting is planned to the end of 2023. Several medals and other forms of prizes have been awarded to employees of the Institute (7.2-7.4). We have also applied to the Czech Academy of Sciences for the certificate called Emeritus employee for our employees (see 7.2 and 7.7); thus, we supported seniority. Via such activity, retired scientists have access to the workplace and can attend the library, scientific meetings, etc.
Timing: report for 2022-2023.
Responsible Unit: HR Award Team, Attestation Commission, Director of the Institute
Responsible Sub-Group: Eva Bártová, Kateřina Svobodová, Gabriela Ambrožová, Olga Nováková
Indicator(s)/Targets:  Principles of equality have been improved and new benefits were established (using also social fund). Our plan is to support social activity that will be available for all R1-R4 categories. Measurable indicator: number of employes with some benefit/total number of employes at given category (women, various social categories, atc). We estimate this percentage to achieve approximately 70%. Action 7 has high priority for HRS4R.
Current Status: Action 7 is completed, however, the initiated activities will continue in future. The gender part will be continued in the next period 2024-26 as an independent action.

Action 8. (text from the Action Plan)
Title: Education courses
Detailed information: Leadership and management skills are critical for a successful career in science. Employees of our Institute will be educated on how to be group leaders. The aim is to explore attendees' approaches to leadership. Negotiation skills in science: This workshop will focus on negotiation. Participants will gain understanding and mastery of the negotiation process, which will support them in reaching their professional goals. Workshop for female scientists: both professional and personal aspects of employment will be discussed. This course, however, is tailored specifically to women scientists to facilitate sharing experiences and insights. Language courses in Czech and English: the Academy of Sciences organizes many language courses specializing especially in English. Within HR Award implementation, we are going to hire an English-speaking lector who will be available for department and group leaders. This lector will provide language consultations including written and spoken language. Course on intelectual Property Rights. In order to improve the knowledge o scientists in this area, course on IPR will be organized. Course of biostatistics and bioinformatics: Employees of the Institute of Biophysics are interested in the course of biostatistics and bioinformatics that will help them to perform appropriate statistical analysis of their scientific results. A course in graphics or alternatively ad hoc specialist in graphics. This specialist will be helpful for graphical illustrations used for scientific papers and oral presentations in PowerPoint. 
GAP Principles: 2, 4, 7, 28, 30, 31, 33, 38, 39
Timing: We aim to organize the following courses: biostatistics, ethics in science, rhetoric, management of science, academic writing and lecturing, eLearning, knowledge on graphical software, language courses, GDPR course, ERC project application, science evaluation, etc. These courses will be organized gradually during 2022-2023, the exact data will be given for each sub-action.
Responsible Unit: Steering Committee
Indicator(s)/Targets: These courses will be available for all R1-R4 categories, indicators are provided in a Table summarizing IBP activities - see Strategy document on IBP web page for HRS4R. This table is showing the number of participants in the individual course. Indicators and measurable indicators will be given for each sub-action as follow. High priority for HES4R, average priority for institutional strategy.
Current Status: In progress
Remarks:

Sub-Action 8.1
Title: Introduction to Science Evaluation (2 hours) (.pptx)
Lecturer: Stanislav Kozubek
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: January 26, 2022 
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4), targetted to PhD students. Number of participants exceeded the supposed one, the measurable indicator is 100%. Action 8.1 has high priority for institutional strategy, average priority for HRS4R.
Number of participants: 25
Current Status: Completed
Remarks: According to the Action plan we had 10-15 participants, e.i. the goal of this course was fulfilled to 100%. The course have been targetted to PhD students and prezented in Czech language.

Sub-Action 8.2
Title: Rhetoric (The ability of cultivated speech, the art of expressing oneself well, formulating one s opinion, presenting oneself, and the ability to respond well to questions) (picture)
Lecturer: Vladka Hagenová
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: February 17, 2022 (10-16 h)
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4). Number of participants: 14 corresponded to the supposed one, the measurable indicator is 93% (14 form 15 maximum possible). The proportions of individual categories were: R1/R2/R3/R4=43%/36%/14%/7% (near to the plan). Action 8.2 had high priority for HRS4R, average priority for institutional strategy.
Number of participants: 14
Current Status: Completed
Remarks: According to the Action plan the number of participants could be up to 15, e.i. the goal of this course was fulfilled to 93%. However, several our employes have had attended this course earlier.

Sub-Action 8.3
Title: Biostatistics - 3 days 8.-10.3.2022 from 12:30 - 16:30 (picture)
1. day
- Introduction to biostatistics - comparability, reliability, significance etc
- Types of data - cathegories and quatitative data
- Visualization of variables (absolute and relative frequency, pie and column plots) and quantitative variables (average, median, dispersion, standard deviation, quantiles, histogrames, boxplots)
- Tests of hypotheses (test significance, p-value)
- Statistical tests (quantitative as well as qualitative variables)
2. day
- Contingence tables - OR (odds risk) and RR (relative risk), sensitivity, specificity
- Correlation coefficient (Pearson and Spearman) and regression analysis (linear and logistic regression)
- ROC analysis, sensitivity, specificity, area under the curve (AUC), classification of patients
- CART (Classification and regression tree)
- Analysis of survivatl (Kaplanův-Meier estimation, Cox model of proportional risk, median of survival, LogRank test)
3. day
- practical training
Lecturer: Dr. Michal Svoboda
GAP Principles: (++) 4. Professional attitude, (+/-) 7. Good practice in research,  (++) 38. Continuing Professional Development, (+/-) 39. Access to research training and continuous development
Timing: March 8.10.3.2022 (12:30-16:30 h)
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4). Number of participants: 13 corresponded to the supposed one, the measurable indicator is 87% (13 form 15 maximum possible). Lower number of participants was favourable for practical part. The proportions of individual categories were: R1/R2/R3/R4=50%/25%/8%/17% (less qualified scientists attended the course with higher probability). Action 8.3 had high priority for HRS4R, as well as for institutional strategy.
Number of participants: 13
Current Status: Completed
Remarks: 

Sub-Action 8.4
Title: ERC grants (types of projects, criteria, evaluation, financial aspcts, example of successful application) (picture)
Lecturer: Petra Fedorová (NCP for ERC grants), Aneta Kašlíková, Pavel Plevka
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: 12 April, 2022 (13-16 h)
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4). Number of participants: 10 corresponded to the supposed one, the measurable indicator is 67% (10 form 15 maximum possible), which was due to the focus on advanced scientists (5 R4 scientists were present). Action 8.4 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 12
Current Status: In Progress
Remarks:

Sub-Action 8.5
Title: Language courses (General English B1/II, General English B2/II, English for doctorands, Advanced English with native speaker, English for academic purposes, Communicatin and writing development ONLINE)
Lecturers: Vogel Radek, LeBlanc Michele, Škarková Eva
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: all courses take place weekly starting from September 9, 2021 to June 19, 2022
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4), distribution among the categories corresponds to our preliminary estimation: 25% each category (2 participants are involved in 2 types of courses, 2 participants are technicians). Number of participants: 12 from 15 supposed, the measurable indicator is 80% (12 form 15 planned). Action 8.5 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 12
Current Status: In Progress
Remarks: The course is continued

Sub-Action 8.6
Title: Computer graphics (Adobe Photoshop, Corel Draw, MS PowerPoint) (picture)
Lecturers: Vít Zelený
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: May 17, 2022
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4), distribution among the categories: R1=38%, R2=38%, R3=8%, R4=15%. Number of participants: 13 from 15 supposed, the measurable indicator is 87% (12 form 15 planned). Action 8.6 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 13
Current Status: Completed
Remarks: The participants requested continuation of the course for 3D graphics

Sub-Action 8.7
Title: Gender in leadership
Detailed information: After an introductory circle of a lecturer and participants, were introduced concepts such as gender, gender stereotypes, socialization, and the possibility of avoiding stereotypes. Later the attention was paid to case studies: Advertising, Remuneration, Reconciliation of work and private life, Goods and services, (Sexual) harassment. An assessment of case studies of non-equal treatment took place in groups. Then the individual cases were discussed with members of other groups, as a tool for solving the cases was used a concept of a shared burden of proof. Following topics were introduced through a discussion of the specific circumstances of the individual cases: (1) Areas and grounds of discrimination protected by the Anti-Discrimination Act, (2) Direct discrimination, indirect discriminationIndirect discrimination, (3) (Sexual) harassment, (4) Persecution, instruction, incitement to discrimination, (5) Shared burden of proof. In the end, as a summary, the lecturer briefly focused on 2 general questions: (1) Why promote equality between women and men? (international and national legal obligations, existence of inequalities, public opinion, 5 arguments for gender equality) (2) How to promote equality between women and men. Participants were cooperative, informed, active. An interest was visible from the detailed discussion. The discussion was constructive and aimed at finding solutions to the often
complex problems that equal treatment brings. Discussed situations are repeatedly on the borderline between the law and ideas of each person about rules of human coexistence, on the borderline between work and private life. Through interaction and through the search for their own solutions to the case studies submitted, participants had the opportunity to experience the complexity of the agenda themselves. They were informed about possible solutions to non-equal treatment not only through sanction mechanisms, so-called ex post solutions, but also about the need for prevention and education 
Lecturer: Mgr. et Mgr. Pavla Špondrová
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: June 22, 2022
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4), distribution among the categories: R1=40%, R2=40%, R3=10%, R4=10%. Number of participants: 20 from 20 supposed, the measurable indicator is 100%. Action 8.6 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 20
Current Status: Completed
Remarks: The participants requested continuation of the course for other gender issues

Report for 2022
Title: Report on education courses realized in 2022
Detailed information: Eight courses have been organized for the employees of our Institute in 2022 in order to improve their abilities in various aspects. The ability of cultivated speech, the art of expressing oneself well, formulating one s opinion, presenting oneself, and the ability to respond well to questions was presented at the course on rhetoric by V. Hagenová, biostatistics was comprehesively presented by M. Svoboda in a very intensive way (3 days course) starting from the theory up to practical training, the evaluation of science and its problems was introduced in the presentation of S. Kozubek, ERC grants (types of projects, criteria, evaluation, financial aspcts, example of successful application) were prezented by P. Fedorova (NCP for ERC), language courses are continuously provided by R. Vogel, M. LeBlanc and E. Škarková, Computer graphics (Adobe Photoshop, Corel Draw, MS PowerPoint) was comprehensively prezented by V. Zelený, and gender problems were intruduced in the lecture by P. Špondrová „Gender in leadership“.
Timing: report for 2022.
Responsible Unit: HR Award Team, Attestation Commission, Director of the Institute
Indicator(s)/Targets:  We have organized 8 courses, there are further courses remaining for the next year: GDPR course, management in science, course on intellectual properties and patent applications, further language courses (from our AP). In addition, we plan to organize EMBO course on writing papers and Excell programming course (according to interest). These courses will be available for all R1-R4 categories, indicators are provided in a Table summarizing IBP activities - see Strategy document on IBP web page for HRS4R.  Measurable indicator: number of employes participating/number of employees interested (here we achieved 80-100%). Action 8 has high priority for HRS4R, however, it strongly contributes to the institutional strategy.
Current Status: Completed for 2022

Sub-Action 8.8
Title: Horizon Europe, MCSF, and ERC grants (calls specific for our institute, criteria, evaluation, financial aspcts, example of successful application) program can be seen here. Photo can be seen here.
Lecturer: Ing. Naďa Koníčková, Dr. Monika Vrajová, Ph.D., Mgr. Lyudmyla Tysyachna
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: 22 February, 2023 (12-15 h)
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4). Number of participants: 15 corresponded (from all deparments) to the supposed one, the measurable indicator is % 100 (all departments were involved) (10 form 10 maximum possible). Action 8.8 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 15
Current Status: Completed
Remarks:

Sub-Action 8.9
Title: Management and Leadership in a nutshell (program can be seen here), illustration photo (here).
Lecturer: PhDr. Zdeňka Brázdová
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: 28 March, 2023 (9-16 h)
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4) with preference for R4 cathegory. Number of participants fixed by lecturer: 15 (from all deparments), R1: 10%, R2: 40%, R3: 20%, R4: 30%, the measurable indicator is 100% of possible numer (all departments were involved). Action 8.9 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 15
Current Status: Completed
Remarks:

Sub-Action 8.10
Title: Writing of scientific publication, illustration photo (here).
Detailed information: On March 30-31, 2023 a scientific writing course led by Céline Carret and aimed at young researchers and doctoral students was realized. The course covered a number of aspects related to the presentation of scientific work. The main topics were clear and concise communication of the essence of the research and its main ideas, the logic and continuity of the text and the structure and clarity of scientific articles and abstracts. The choice of suitable graphics for publications, form, was also discussed data presentation and tailoring the presentation to a specific audience. On the participant's request was also discussed in detail beyond the standard scope of the course preparation of a letter to the editor (cover letter) with an emphasis on form and importance a clear expression of the novelty and importance of research and demonstrations of countermeasures examples. The course was highly interactive with plenty of room for discussion and to the questions of the participants. It also included a number of practical exercises such as writing abstract or preparation of a short verbal presentation of one's own research (the so-called elevator pitch). These exercises also included mutual feedback bonding, when participants evaluated each other's work, passed on experiences and suggested improvements. Overall, the course provided a strong foundation for development skills in the field of scientific communication and was evaluated by the participants themselves as very beneficial and inspiring.
Lecturer: Céline Carret
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: March 30-31, 2023
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4) with preference for R1 and R2. Number of participants 18 (from all deparments), R1: 67%, R2: 33%, the measurable indicator is approximately 90% of possible maximum numer (all departments were involved). The questionnaire on the course usefulness is shown here. Similar questionnaire sent by the EMBO lecturer has shown once again that the course was highly appreciated by the participants (here).Action 8.10 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 18
Current Status: Completed

Sub-Action 8.11
Title: Equality between women and men (photo can be seen here)
Detailed information: (1) the course was intended for all interested parties, (2) the course was focused on the topic of "gender stereotypes", what we have, how they are harmful and in which areas they specifically have negative effects on both women and men; (3)  some other potentially discriminatory cases have been discussed, (4) space for explaining the principles of equal treatment as they result from the anti-discrimination law has been dedicated, which so many missed in the past lecture
Lecturer: Mgr. et Mgr. Pavla Špondrová
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: April 5, 2023, 9:30-11:30
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all employees of the Institute distribution among the categories: R1=40%, R2=40%, R3=10%, R4=10%. Number of participants: 20 from 20 supposed, the measurable indicator is 100%. Action 8.11 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 20
Current Status: Completed

Sub-Action 8.12
Title: Excel 1 (most common use of Microsoft Excel), photo can be seen here or here, presentation sent to the participants.
Detailed information: Excel 1 represents basic course on the use of Microsoft Excel, i.e. definitions of workbook, sheet, cell, selection and field; tools such as quick access, menu of cards, cell address,  sheets and sliders, magnifying in excel, types of mouse cursor, tables (standard and pivot tables), graphs, printing,  sorting, filters, finding and substituting, files from external sources, merging and splitting of text, inserting of formulas into cells and fields, simple formulaes such as sum, average, stretching along columns or rows, basic functions, drop-down list, conditions, finding functions in excel, transition of values to text, creation of plots, working with several or many files, creation of macros.      
Lecturer: Stanislav Kozubek
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: May 18, 2023 (13 hod)
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4). Number of participants: 17 R1 - 3, R2 - 4, R3 - 2, R4 - 0, non-scientific workers -  8. Action 8.12 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 17
Current Status: Completed

Sub-Action 8.13
Title: Seminar on Cybersecurity.
Detailed information: The following questions have been answered: How to work with user passwords? How e-mail works? How to recognize a fake email? What is phishing?
Lecturer: David Král (IT department)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: June 28, 2023, October 5, 2023, 0ctober 19, 2023, October 30, 2023, November 21, 2023
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4). Number of participants: 28 of all categories.  Action 8.13 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 28
Current Status: Completed

Sub-Action 8.14
Title: Course on physiotherapy 1 and 2 (photos - theoretical and practical parts)
Detailed information: This course will involve theoretical and practical parts. The presentation will include the basics of ergonomics in the workplace, the principles of trunk stabilization and posture, simple exercises to intersperse sedentary work. Practical part will be held in our minigym and will involve examples of basic exercises and their individual adaptation.
Lecturer: Mgr. Antonín Tomáš - physiotherapist
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: September 19 and 22, 2023 (9 hod), practical parts started at 9 h in 30 min intervals for groups of 5 participants.
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4). Number of participants: 33 of all categories (R1-7, R2-10, R3-7, R4-2, Other - 7). Action 8.14 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 33
Current Status: Completed

Sub-Action 8.15
Title: Applying design principles to schematic figures, illustration photos (1,2).
Detailed information: On September 27, 2023, the EMBO course "Applying design principles to schematic figures" was held at BFÚ, led by designer and trainer from EMBO, Sandra Krahl. The course was aimed primarily at the education of postdoctoral fellows and researchers. The main goal, as the name implies, was to understand and master the basic principles of creating diagrams so that they are presented correctly both visually and in terms of content. For this purpose, the participants were introduced to the entire process of schema creation, the so-called conceptualization principle, which first of all focuses on the audience to whom the schema will be presented, then defines the main idea of ​​the entire schema, and only at the end focuses on the creation of the schema itself. This principle was subsequently presented in detail through many examples. Similarly, other techniques that increase the quality of schemes were introduced. These techniques mainly focus on the possibilities of highlighting the main idea of ​​the scheme through the principle of "three layers", which works with the color and size of individual elements. At the end of the course, the participants were introduced in detail to the issue of image resolution for publication in various media, such as a scientific article, presentation or poster message. For a better understanding and assimilation of all discussed topics, the participants actively prepared their own schemes either in groups or later individually as part of the practical part of the course. Through joint discussions, they subsequently received feedback from the other participants and the lecturer. The course was very beneficial for all participants. The obtained information can be implemented in a wide range of scientific activities.
Lecturer: Sandra Krahl
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: September 27, 2023
Responsible Unit: Steering Committee, Working Group, organized by H. Polášek-Sedlášková
Indicator(s)/Targets: Available for all categories (R1-R4) with preference for R1 and R2. Number of participants 16 (from all deparments), R1: 47%, R2: 27%, the measurable indicator is approximately 90% of possible maximum numer (all departments were involved). Action 8.15 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 16
Current Status: Completed

Sub-Action 8.16
Title: Excel 1 (most common use of Microsoft Excel), presentation sent to the participants.
Detailed information: Excel 1 represents basic course on the use of Microsoft Excel, i.e. definitions of workbook, sheet, cell, selection and field; tools such as quick access, menu of cards, cell address,  sheets and sliders, magnifying in excel, types of mouse cursor, tables (standard and pivot tables), graphs, printing,  sorting, filters, finding and substituting, files from external sources, merging and splitting of text, inserting of formulas into cells and fields, simple formulaes such as sum, average, stretching along columns or rows, basic functions, drop-down list, conditions, finding functions in excel, transition of values to text, creation of plots, working with several or many files, creation of macros.      
Lecturer: Stanislav Kozubek
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: October 23, 2023 (10 h)
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories (R1-R4). Number of participants: 7 R1 - 0, R2 - 4, R3 - 0, R4 - 0, non-scientific workers -  3. Action 8.16 had high priority for both HRS4R, and for the institutional strategy.
Number of participants: 7
Current Status: Completed

Report for 2022-2023
Title: Report on education courses realized in 2022-2023
Detailed information: 8 courses have been organized for the employees of our Institute in 2022 and additional 8 courses (the language course continued) in 2023 in order to improve their abilities in various aspects. The ability of cultivated speech, the art of expressing oneself well, formulating ones opinion, presenting oneself, and the ability to respond well to questions was presented at the course on rhetoric by V. Hagenová, biostatistics was comprehesively presented by M. Svoboda in a very intensive way (3 days course) starting from the theory up to practical training, the evaluation of science and its problems was introduced in the presentation of S. Kozubek, ERC grants (types of projects, criteria, evaluation, financial aspects, example of successful application) were prezented by P. Fedorova (NCP for ERC), language courses are continuously provided by R. Vogel, M. LeBlanc and E. Škarková, Computer graphics (Adobe Photoshop, Corel Draw, MS PowerPoint) was comprehensively prezented by V. Zelený, and gender problems were intruduced in the lecture by P. Špondrová „Gender in leadership“ and continued by "Equality between women and men" in 2023. Writing of scientific publication was introduced by Céline Carret from EMBO. Introduction to Excel basic functions was prezented by S. Kozubek and Seminar on Cybersecurity was prezented by D. Král from our IT department. Course on physiotherapy with 33 participans prezented A. Tomáš.
Timing: report for 2022-2023.
Responsible Unit: WG, HR Award Team, Director of the Institute
Responsible Sub-Group: Stanislav Kozubek, Bačovský Václav, Zuzana Machálková, Olga Nováková
Indicator(s)/Targets:  We have organized 16 courses, there are further courses remaining for the next year: GDPR course, management in science, course on intellectual properties and patent applications, further language courses. In addition, we plan to organize EMBO course on writing papers and Excell programming course (according to interest). These courses are available for all R1-R4 categories. The number of participants fluctuated between 7-33; average number was 17,5. Measurable indicator: number of employes participating/number of employees interested to participate (here we achieved 80-100%). Action 8 has high priority for HRS4R, however, it also strongly contributes to the institutional strategy.
Current Status: Completed for 2022-2023, this activity will be continued in the next year involving both new topics and extending already successfully realized ones.

Action 9. (text from the Action Plan)
Title: Child-corner (nursery directly at the Institute)
Detailed information: Currently, we focus on the operation of a nursery garden; it will serve as institutional support for families with children. We consider the fact that the availability of public nurseries is considerably limited due to their low number, and we also consider low support from the government of the Czech Republic. We plan to establish a nursery with variable possibilities; children can attend this facility irregularly, that is mostly for several days a month, and/or regularly, that is every day. For parents, this nursery will provide effective service with huge variability. Nurseries can usually be entered from the age of 12 months. The admission process for children will be relatively flexible and dependent on parents' demands. The number of families using nurseries will be provided to the commission evaluated IBP implementation program. Contracts with external body-provided nurseries will be published on the National Register of Contracts.
GAP Principles: 9, 10, 24
Timing: Implementation 2021-2024; at the last quarter of each year the report about the state of child-corner will be provided.
Responsible Unit: HR Award Team - Steering Commitee, Director
Indicator(s)/Targets: This action is focused to the improvement of working conditions of women with children. This activity will be available for all R1-R4 categories in the following percentage: 30/30/20/10. Approximately 5-8 children per semester will attend this nursery. Annually, we will organize meetings with parents in order to discuss how to improve their working conditions. The number of families using nurseries will be mentioned in the final institutional report for stakeholders annually. This report will also be translated into English and will be posted on the institutional web page, in part showing activities within the HR Award. Measurable indicator: the nuber of families using nurseries/the number of families requiring it. Action 9. has high priority for HRS4R, average priority for institutional strategy.
Current Status: In progress
Remarks:

Sub-Action 9.1
Title: Establishment of the Elánek children's group (Operating rules)
Detailed information: We have established Elánek children's group according to Act 247/2014 Coll. with the capacity 6 children. The regime requirements, interior spaces, methods of dealing with laundry and othe details are described in the Operation rules.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: January 1, 2022
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories. Number of participants: 4 from 4 supposed, the measurable indicator is 100%. Action 9.1 had high priority for HRS4R.
Number of participants: 4
Current Status: Completed

Sub-Action 9.2
Title: Children's Day (pictures 1, 2, 3, 4, 5)
Detailed information: Children's places: 1. lighthouse construction - boards, cubes, small cubes 2. swamp crossing - bucket stilts, cube stilts 3. water skis 4. fishing - small and large fish 5. pirate duel 6th ship sinks - carrying water 7. throw to the goal - cans, rings, bolobol 8. pirate trail - paddle tennis, bats, track, croquet. Workshops: 1. pearl necklace - stringing pasta, children can then color it 2. pirate hat, eye tape - pre-cut template - connects with a stapler and slows down 3. making a pirate sword or saber from a modeling balloon 4. Pumps, jellyfish, octopuses, coloring books, - creation from paper, crepe and glue. Other options: Body and face painting, using stencils and tattoos. Joint creation from modeling balloons. Joint competitions, according to the interests of children and adults. Special experience: pony riding. Small refreshments has been provided at the event.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: June 3, 2022
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories. Number of participants: 50 from 60 supposed, the measurable indicator is 83%. Action 9.2 had high priority for HRS4R.
Number of participants: 50
Current Status: Completed
Remarks:

Report for 2022
Title: Report about the child corner and activites for parents with children in 2022
Detailed information: We have established a nursery (Elánek group) with variable possibilities; children can attend this facility irregularly, that is mostly for several days a month, and/or regularly, that is every day. For parents, this nursery  provides effective service with marked variability. Nurseries can usually be entered from the age of 12 months. The admission process for children is relatively flexible and depends on parents' demands.
Timing: report for 2022.
Responsible Unit: HR Award Team - Steering Commitee, Director
Indicator(s)/Targets:  This action is focused to the improvement of working conditions of women with children. The activity is available for all R1-R4 categories. Up to 6 children per semester may attend this nursery (according to the demand). We have organized meetings with parents in order to discuss how to improve their working conditions during the „Summer schools“ (see 14.1-14.2) . The number of families using nurseries is currently 4 from 5 demanding in this year (one family used other nursery in the town). This report will also be translated into English and will be posted on the institutional web page, in part showing activities within the HR Award. Measurable indicator: the nuber of families using nurseries/the number of families requiring it (80%). Action 9. has high priority for HRS4R, average priority for institutional strategy.
Current Status: Completed for 2022

Sub-Action 9.3
Title: Children's Day (pictures 1, 2, 3)
Detailed information: Children's places: 1. lighthouse construction - boards, cubes, small cubes 2. swamp crossing - bucket stilts, cube stilts 3. water skis 4. fishing - small and large fish 5. pirate duel 6th ship sinks - carrying water 7. throw to the goal - cans, rings, bolobol 8. pirate trail - paddle tennis, bats, track, croquet 9. bouncy castle. Workshops: 1. pearl necklace - stringing pasta, children can then color it 2. pirate hat, eye tape - pre-cut template - connects with a stapler and slows down 3. making a pirate sword or saber from a modeling balloon 4. Pumps, jellyfish, octopuses, coloring books, - creation from paper, crepe and glue. Other options: Body and face painting, using stencils and tattoos. Joint creation from modeling balloons. Joint competitions, according to the interests of children and adults. Special experience: pony riding. Small refreshments has been provided at the event.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: June 2, 2023
Responsible Unit: Steering Committee, Working Group
Indicator(s)/Targets: Available for all categories. Number of participants (children): 62 from (Institute of Biophysics 55, 7 from Institute of Physics of Materials), 55 supposed, the measurable indicator is over 100%. Action 9.3 had high priority for HRS4R.
Number of participants: 62
Current Status: Completed

Sub-Action 9.4
Title: The Elánek children's group is functioning (see here)
Detailed information: The established Elánek children's group with the capacity 6 children is functioning in both 2022 and 2023 (as described in the Operation rules).
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: 2022-2023
Responsible Unit: Working Group, Steering Committee
Indicator(s)/Targets: Available for all categories. Number of participants: 6 from 6 supposed, the measurable indicator is 100%. Action 9.4 has high priority for HRS4R.
Number of participants: 6
Current Status: Completed

Report for 2022-2023
Title: Report about the child corner and activites for parents with children in 2022-2023
Detailed information: We have established a nursery (Elánek group) with variable possibilities; children can attend this facility irregularly, that is mostly for several days a month, and/or regularly, that is every day (five days a week). For parents, this nursery  provides effective service with marked variability. Nurseries can usually be entered from the age of 12 months. The admission process for children is relatively flexible and depends on parents' demands. Financial support for the group depends on the number of children (6 children is obligatory).
Timing: report for 2022-2023.
Responsible Unit: Working Group, Steering Commitee, Director
Responsible Sub-Group: Stanislav Kozubek, Jana Lunerová, Milada Kořínková, Luděk Havran
Indicator(s)/Targets:  This action is focused mainly to the improvement of working conditions of women with children. The activity is available for all R1-R4 categories. Up to 6 children per semester may attend this nursery (according to the demand). We have organized meetings with parents in order to discuss how to improve their working conditions during the „Summer schools“ (see 14.1-14.2) . The number of families using nurseries was 4 from 5 demanding in 2022 (one family used other nursery in the town).  There are 6 children in the Elánek group in 2023.
Measurable indicator: the nuber of families using nurseries/the number of families requiring, it is 80-100%. Action 9. has high priority for HRS4R, average priority for institutional strategy.
Current Status: Completed (the activity is not involved in HR AP for 2024-2026, however, Elánek group will continue in the same extent in future)

Action 10. (text from the Action Plan)
Title: Lectures provided by foreign scientists will be selected by young scientists working at the IBP and by PhD students. We will also organize director's collegium, meeting of researchers, meetings of WG and SC, meetings of parents in science
GAP Principles: 23, 38, 39
Timing: The call for nominations of speakers will be made at the beginning of every new year (I. quarter). Students will select 2-3 foreign speakers that will be invited for a lecture. A discussion on the scientific results and career possibilities will be organized annually since 2021. Also, several times a year, we will organize director's collegium, meeting of researchers, meeting of WG and SC, meeting of parents in science. Exact dates will be shown during the implementation phase.
Responsible Unit:  Steering Commitee, WG
Indicator(s)/Targets: It is essential to organize lectures, institutional seminars, meetings and discussion clubs. Minutes of meetings will be archived and translated into English. Meetings will be open for R1-R4 categories and will be organized according to the schedule published in the table, in the Strategy document of the IBP. The participation of scientists in these activities will be properly described in the Minutes of the meeting. Measureable indicators: number of participants/number of available employes at given category (e.g. number of participants at the directors collegium/number of members of the collegium). Action 10. has high priority for institutional strategy, average priority for HRS4R..
Current Status:
Remarks:

Sub-Action 10.1
Title: Methodological Symposium on Machines and Methods (meeting of researchers - picture)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturer: Václav Brázda, Soňa Legartová, Václav Bačovský
Timing: March 25, 2022 (10-16 h)
Responsible unit: Steering Commitee
Indicator(s)/Targets: Exchange of information in the field of advanced microscopy. It involved the following topics: 1) doc. Mgr. Václav Brázda, Ph.D.: Atomic Force Microscopy; 2) Mgr. Soňa Legartová, Ph.D.: Lifetime Fluorescence: TCSPC and FRET; 3) Václav Bačovský, Ph.D.: 3D SIM, lightning deconvolution and AiryScan detection. The activity was attended mainly by researchers, however it was available for all categories (R1-R4): R1/R2/R3/R4=20/18/7/7. Measurable indicator (number  of participants/number of scientists working in this field): 80%. Action 10.1 had high priority for both institutional strategy and for HRS4R.
The minutes from the seminar are here.
Number of participants: 53
Current status: Completed

Sub-Action 10.2
Title: Lecture on Non-B DNA and evolution (the invitation to the lecture is here, picture is here)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturer: prof. Kateryna Makova
Timing: April 27, 2022 (13-15 h)
Responsible unit: Steering Commitee
Indicator(s)/Targets: The lecture has involved 4 directions of research of prof. K. Makova: 1. Replication of non-B DNA (slowing down of polymerase, increase of the number of errors), 2. Mutation frequency of non-B DNA (SNP in G-quadruplexes), 3. Evolution of non-B DNA, 4. Sequencing errors increase in non-B DNA sequences. The activity was attended by all categories of scientists (R1-R4), the total number was 43, R1=17 (40%), R2=13 (30%), R3=5 (12%) and R4=8 (19%). Measurable indicator (number of participants/number of scientists working in this field): 100% (this lecture was extremely interesting and visited even by scientists workin out of the field). Action 10.2 had high priority for both institutional strategy and for HRS4R.
Number of participants: 43
Current status: Completed

Sub-Action 10.3
Title: From active demethylation to DNA repair in the context of early mammalian development (invitation see here)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturer: dr. Helena Fulková
Timing: May 3, 2022 (13-15 h)
Responsible unit: Steering Commitee
Indicator(s)/Targets: The lecture was focused to epigenetics of oncogenesis, DNA repair and early mammalian development. The activity was attended by all categories of scientists (R1-R4), the total number was 26, mainly scientists involved in the field of epigenetics: R1/R2/R3/R4=10/7/2/5.  Measurable indicator (number of participants/number of scientists working in this field): estimated to 80% (this lecture was interesting but focused to very narrow field of science). Action 10.3 had high priority for institutional strategy, average priority for HRS4R.
Number of participants: 26
Current status: Completed

Sub-Action 10.4
Title: In vivo and in vitro study of 17beta estradiol on altered age related neuronal parameters in naturally menopausal rats (picture)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturer: Prof. Pardeep Kumar
Timing: May 6, 2022
Responsible unit: Steering Commitee
Indicator(s)/Targets: The lecture was focused to age related neuronal parameters and their modification by estradiol. The lecture was focused to very narrow field of science. The total number of participants was 10, mainly scientists involved in the corresponding field. Measurable indicator: difficult to estimate. Action 10.4 had average priority for both institutional strategy and for HRS4R.
Number of participants: 10
Current status: Completed

Sub-Action 10.5
Title: Director's Collegium
Meeting program: 1) Presentation of the holders of internal support projects for the years 2020 and 2021 (doc. C. Hofr, dr. P. Jedlička, dr. A. Cantara, dr. S. Legartová, dr. K. Turková) 2) Information on the director's visions for the next term and current information 3) Information on the photovoltaic power plant (Dr. P. Vacek) 4) Discussion on publishing in MDPI journals
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: June 15, 2022
Responsible unit: Steering Commitee, Director of the Institute
Indicator(s)/Targets: The Collegium consists of all department leaders as well as management representatives and represents an important body for exchange of information and preliminary discussion of current problem, which can be solved at the Board of the Institute. The total number of participants was 21 from 27 members. Measurable indicator: 21/27=78%. Action 10.5 had high priority for both institutional strategy and for HRS4R.
Number of participants: 21
Current status: Completed

Sub-Action 10.6
Title: Establishing meeting of the "Czech Biophysical Association" (minutes)
Introduction: At the beginning, the director of the institute, E. Bártová, informed those present about the process of establishing the association, the reasons for its establishment and other circumstances. The association represents a continuation of the Committee for Biophysics, which ensured cooperation with the worldwide organization IUPAB, to which the Czech Academy of Sciences paid contributions. CAS no longer provides these payments, and therefore it is necessary to find a way to maintain the “Czech biophysical society” and its cooperation with IUPAB. The association should ensure organized activity in the field of biophysics and continuity with IUPAB, including the payment of a contribution. There was extensive discussion about this activity.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: June 23, 2022
Responsible unit: Steering Commitee, Director of the Institute
Indicator(s)/Targets: We take care of the field of biophysics at the level of the Czech Republic. The establishing meeting of the "Czech Biophysical Association" showed interest of the participants to stay at international organizations such as IUPAB or EBSA as well as involve more scientists in the society (list of members). Action 10.6 had high priority for both institutional strategy and for HRS4R.
Number of participants: 11
Current status: Completed

Sub-Action 10.7
Title: Methodological Seminar on Machines and Methods (meeting of researchers - picture)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturer: Jana Krejčí, Karel Souček, Radek Fedr
Timing: June 24, 2022 (10-16 h)
Responsible unit: Steering Commitee
Indicator(s)/Targets: Exchange of information in the field of advanced microscopy. It involved the following topics: 1) Jana Krejčí, Ph.D. was the first to give a lecture entitled "Chisostat – a device with a source of gamma radiation". She acquainted the students with the location and security of the chisostat and the working conditions during its use. She explained the basic concepts when working with the source of gamma-rays and the possibilities of its use. She offered the opportunity to agree on possible cooperation with irradiation of samples. Finally, she answered questions asked by the audience; 2)Karel Souček, Ph.D. provided a lecture on Small Animal Facility. Dr. Souček introduced to the audience the methodology of the  operations with laboratory mice, the type of rooms and the type of mice. He introduced the team and its organization of the daily schedule. He mentioned the methods of fluorescence, luminescence and X-ray techniques, showed some cytokinetic results. In case of interest in cooperation, he referred to the contact Mgr. Víchová. Again, questions were raised after the lecture, to which Dr. Souček answered. 3)The last lecturer was prezented by Mgr. Radek Fedr, who spoke about methods of highthroughput microscopy and about the use and application of highthroughput microscopy methods. He shared the results of the given methods and offered the possibility of cooperation. Even after this lecture, questions were answered. The activity was attended mainly by researchers, however it was available for all categories (R1-R4). They participated in the following proportions: R1=42%, R2=29%, R3=6%, R4=10%. Measurable indicator (number  of participants/number of scientists working in this field): 80%. Action 10.7 had high priority for both institutional strategy and for HRS4R.
The minutes from the seminar are here.
Number of participants: 31
Current status: Completed

Sub-Action 10.8
Title: Director's Collegium
Meeting program: 1) Presentation of the OP JAK project by the director or the Institute Eva Bártová, 2) Savings of enegy, information on the photovoltaic power plant (Pavel Vacek), 3) Information from economic department (Robin Ulrich), 4) List of selected publications for the national M17+ evaluation (Eva Bártová, Aleš Kovařík), 5) Coins of the Institute will be ordered and awarded on various occasions, 6) Program of the ISAB meeting has been discussed, 7) Crisis plan for the Institute for various calamities will be prepared (Peter Cembis), 8) Compensations for "home office" (information by the director of the Institute).
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: September 22, 2022
Responsible unit: Steering Commitee, Director of the Institute
Indicator(s)/Targets: The Collegium consists of all department leaders as well as management representatives and represents an important body for exchange of information and preliminary discussion of current problem, which can be solved at the Board of the Institute. The total number of participants was 26 from 27 members. Measurable indicator: 26/27=96%. Action 10.8 had high priority for both institutional strategy and for HRS4R.
Number of participants: 26
Current status: Completed

Sub-Action 10.9
Title: Introduction to NanoTemper methods for biophysical characterization of challenging molecular interactions (picture here)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturer: Pawel Kania
Timing: September 29, 2022
Responsible unit: Steering Commitee
Indicator(s)/Targets: The lecture was focused to biophysical methods measuring interactions of biomolecules. The activity was attended by all categories of scientists (R1-R4), the total number was 13, mainly scientists involved in the field of epigenetics. Measurable indicator (number of participants/number of scientists working in this field): estimated to 50% (this lecture was interesting but focused to very narrow field of science). Action 10.9 had high priority for institutional strategy, average priority for HRS4R.
Number of participants: 13
Current status: Completed

Sub-Action 10.10
Title: Extracellular vesicles (international meeting, the invitation see here)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: September 29, 2022, Lecture Hall of the Institute
Organizer: Lukáš Kubala
Responsible unit: Working Group, director of the Institute
Indicator(s)/Targets: In the meeting 20 scientists and students from Medical University of Vienna, Ludwik Hirszfeld Institute of Immunology and Experimental Therapy (Polish Academy of Sciences), Faculty of Medicine, Charles University and from the Institute of Biophysics CAS took part. The results of the corresponding laboratories on extracellular bacteerial vesicles have been prezented. Possibilities of further cooperation have been discussed. Measurable indicator (number of participants from the Institute/number of scientists and students from the Departments) approximately 60%. Action 10.10 have had high priority for institutional strategy as well as for HRS4R.
Number of participants: 20
Current status: Completed

Sub-Action 10.11
Title: ISAB meeting (see Program)
Meeting program:   Introductory prezentation by the director of the Institute, Eva Bártová (see picture). 1) The ISAB statement for OP-JAC project – how to make the project attractive, and we need a short recommendation. 2) Selection of 2 of the best young scientists (students) awarded by the ISAB - the ISAB Award, 3) ISAB opinion if we should publish in MDPI journals, 4) A motivation tool for department leaders how to recruit young scientists with the potential to apply for, e.g., Junior Star and Lumina Queruntur projects (200 000 Euro/year for 4-5 years – to build new teams), 5) Recommendation of prof. Mergny for a new contract that will also be discussed by the Institutional Council – how to continue in cooperation. Director of the Institute, Eva Bártová, prezented the main points of the strategy of the Institute including preparation of the JAK project, publications in MDPI journals or continuation of the SYMBIT project. ISAB discussed these points. See Meetings (here).
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: October 6, 2022
Responsible unit: Steering Commitee, Council of the Institute, Director of the Institute
Indicator(s)/Targets:  ISAB consists of famous foreign scientists: Tom Misteli (NIH, USA), Roland Foisner (Medical University, Wiena, Austria), Ben Luisi (Cambridge University, UK), Elena Ferapontova (Aarhus University of Copenhagen, Denmark), Mary Anne OConnell (Ceitec, Masaryk University, Czech Republic), Giovanni Natile (University of Bari, Italy) and Jiří Forejt (Institute of Molecular Genetic, CAS, Czech Republic). All ISAB members participated on the meeting. Measurable indicator: 100%. Action 10.11 had high priority for both institutional strategy and for HRS4R. 
Number of participants form the Institute: 47
Current status: Completed

Sub-Action 10.12
Title: Methodological seminar "Machines and Methods - Microscopy" (photo see here)
Meeting program:   Special Microscopy - V. Krzyzanek: High-resolution electron microscopy, K. Hrubanova: Clinical microbiology, biotechnology, Cryo-SEM methods, O. Samek: Raman spectroscopy/microscopy
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: October 20, 2022
Responsible unit: Steering Commitee, Council of the Institute, Director of the Institute
Indicator(s)/Targets:  The methodological seminar was dedicated to all categories R1-R4: category/participants: R1/8, R2/7, R3/7, R4/2. Measurable indicator: 100%. Action 10.12 had high priority for both institutional strategy and for HRS4R. 
Number of participants form the Institute: 30
Current status: Completed

Sub-Action 10.13
Title: Cullin-dependent ubiquitin legases in cancer progression
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: Novemer 7, 2022, Lecture Hall of the Institute
Organizer: Lukáš Čermák
Responsible unit: Working Group, director of the Institute
Indicator(s)/Targets: In the meeting 20 scientists and students from Brno region, mainly from the Institute of Biophysics CAS took part. The ratio R1/R2/R3/R4 was 6/6/1/1 participants and 6 students took part in the meeting. In the presentation, new results from cancer biology have been discussed. Measurable indicator (number of present participants from the Institute/number of scientists and students from all Departments) approximately 20%. Action 10.13 have had high priority for institutional strategy as well as for HRS4R.
Number of participants: 20
Current status: Completed

Sub-Action 10.14
Title: IBP CAREER DAY: "Per Aspera ad Astra" (detailed information see here, pictures can be seen here)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturers: Vladimíra Petráková, Martin Vita, Panagiotis Alexiou, Vratislav Košťál 
Timing: November 11, 2022, Lecture Hall of the Institute at 12:30 
Organizer: Hana Polášek-Sedláčková
Responsible unit: Working Group, director of the Institute
Indicator(s)/Targets: Young researchers of the Institute of Biophysics (IBP) of the Czech Academy of Sciences are inviting students and postdocs to IBP career day: Per Aspera Ad Astra focused on future career possibilities in the academic and industrial spheres. During the event, four outstanding scientists have shared stories of their scientific journeys and will lead popular round table discussions on various topics. Measurable indicator (number of participants/number of postdocs and PhD students at the Institute): the number of participants corresponded to the number of young researchers (approx 90%). R1/R2/R3/R4=21/9/2/0+30 students. Action 10.14 have had high priority for institutional strategy as well as for HRS4R.
Number of participants: 62
Current status: Completed

Report for 2022
Title: Report about lectures provided by foreign scientists, director's collegia, meetings of researchers, meetings of WG and SC, meeting of parents in science in 2022
Detailed information: We have organized 4 lectures by foreigh scientists (K. Makova, H. Fulkova, P. Kumar, P. Kania), 3 Methodological Symposia (lecturers: Vaclav Brazda, Sona Legartova, Vaclav Bacovsky, Jana Krejci, Karel Soucek, Radek Fedr, Vladislaf Krzyzanek, Kamila Hrubanova, Ota Samek), 2 Director’s Collegia, a meeting to establish „Czech Biophysical Association“, one ISAB meeting, IBP Career Day (organized by Hana Polášek-Sedláčková) where a discussion on career possibilities has been arranged and International meeting on Extracellular Vesicles organized by L. Kubala. In addition meeting with parents in science has been organized during the Summer school (see Sub-Action 14.1).
Timing: report for 2022.
Responsible Unit: HR Award Team - Steering Commitee, Director
Indicator(s)/Targets:  Invitations and Minutes of these meetings have been archived and translated into English. Meetings are open for R1-R4 categories. The participation of scientists in these activities has been carefully checked. Measureable indicators: number of participants/number of available employes at given category (e.g. number of participants at the directors collegium/number of members of the collegium). In most cases, this indicator ranged between 60% and 100%. Action 10. has high priority for institutional strategy, average priority for HRS4R.
Current Status: Completed for 2022

Sub-Action 10.15
Title: Director's Collegium
Meeting program:
   a) Presentations of the candidates for the internal support projects for the year 2023:
1) dr. V. Tichý: "The role of non-coding RNAN in the initiation of UV-induced DNA damage response"
2) dr. V. Hudzieczek: "Genome-wide analysis of transcription factor binding sites to identify regulatory networks controlled by sex chromosomes"
3) Mgr. Pavel Veverka: "Objasnění funkce proteinu Codanin1 při regulaci depozice histonů prostřednictvím interakce s ASF1 a CDIN1"
4) dr. Jana Lunerová: Epigenetic regulation of bivalent and univalent chromosomes in dogrosesEpigenetic regulation of bivalent and univalent chromosomes in dogroses
   b) Requests of mobility projects:
1) Ondrej Hesko -Slovinsko, Lublaň, Analytical Chemistry Laboratory, National Institute of Chemistry
2) Tereza Mikešová - Umea University, Švédsko
    c) Information about the progress of HR Award action plan. S. Kozubek (responsible person for HRAW) informed Collegium about individual Actions and the plan for the next year.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: January 20, 2023
Responsible unit: Steering Commitee, Collegium, Director of the Institute
Indicator(s)/Targets: The Collegium consists of all department leaders as well as management representatives and represents an important body for exchange of information and preliminary discussion of current problem, which can be solved at the Board of the Institute. The total number of participants was 21 (members of the Collegium) from 27 members of the Collegium and 6 candidates for internal support. Measurable indicator: 21/27=78%. Action 10.15 had high priority for both institutional strategy and for HRS4R.
Number of participants: 21
Current status: Completed

Sub-Action 10.16
Title: Post-SYMBIT seminar (photo see here)
Detailed information: The seminar is organized within sustainability period of the project "Structural gymnastics of nucleic acids: from molecular principles through biological functions to therapeutic targets" This seminar involved the following lectures: J. Palacky: "Selected Applications of Raman Spectroscopy for the Study of Nucleic Acids", S. Hason: "Electrochemistry of Guanine at Graphene-Based Electrodes: from describing guanine oxidation to detecting formation of supramolecular motifs"
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: March 2, 2023, Lecture Hall of the Institute
Organizer: Miroslav Fojta
Responsible unit: Working Group, Steering Committee, director of the Institute
Indicator(s)/Targets: In the seminar 28 scientists and students from Brno region, mainly from the Institute of Biophysics CAS took part. The ratio R1/R2/R3/R4 was 10/5/7/2 and 4 students took part in the meeting. Measurable indicator (number of present participants from the Institute/number of scientists and students from all Departments participating in the SYMBIT project) approximately 60%. Action 10.16 have had high priority for institutional strategy as well as for HRS4R.
Number of participants: 28
Current status: Completed

Sub-Action 10.17
Title: IBP meeting on Machines and Methods (Invitation), illustrating photos (here).
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturer: Jiří Vorel
Timing: March 23, 2023 (13 h), IBP lecture hall
Responsible unit: Steering Commitee, director of the Institute
Indicator(s)/Targets: MetaCentrum - grid service for scientific computations and collaborative research will be prezented. The activity will be attended mainly by researchers, however it is available for all categories (R1-R4). Expected proportions: R1=31%, R2=38%, R3=19%, R4=6%. Measurable indicator (number of participants/number of scientists working in this field): 80%. Action 10.17 had high priority for both institutional strategy and for HRS4R.
Number of participants: 32
Current status: Completed

Sub-Action 10.18
Title: Water and electrochemistry (photos can be seen here )
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: May 5, 2023, Lecture Hall of the Institute
Organizer: Martin Pivokonsky
Responsible unit: Working Group, director of the Institute
Indicator(s)/Targets: In the meeting the director of the Institute of hydrodynamics, CAS, Prof. Martin Pivokonsky, Ph.D. and Mgr. Stanislav Hason, Ph.D. from the Institute of Biophysics, CAS presented their scientific results related to the quality of water resources. Possibilities of further cooperation have been discussed. Measurable indicator (number of participants from the Institute/number of scientists working in the field or related fields of science) approximately 80% (33 participants, R1 - 7, R2 - 10, R3 - 8, R4 - 5). Action 10.18 had had high priority for institutional strategy as well as for HRS4R.
Number of participants: 33
Current status: Completed

Sub-Action 10.19
Title: Merck seminar "Antibody zone"
Detailed information: Presentations on: Recombinant monoclonal antibodies as green alternatives, Turning the PAGE (SDS-PAGE/WB workflow tips and tricks"
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturers: Eliska Zizkova, Stanislav Kukla
Timing: May 24, 2023 (13-14:30), Seminar room No. 136, IBP CAS
Responsible unit: Steering Commitee, director of the Institute
Indicator(s)/Targets: The activity was attended mainly by young researchers, however it was available for all categories (R1-R4): R1=6 participants, R2=4 R3=0 R4=0. Measurable indicator (number  of participants/number of scientists working in this field): 20%. Action 10.19 had high priority for both institutional strategy and for HRS4R.
Number of participants: 12
Current status: Completed

Sub-Action 10.20
Title: Meeting of the Czech Biophysical Association: "Focused on Microscopic and Biophysical Techniques" (Invitation and Program), introductory photo see here.
Short program:
   Wednesday June 7, 2023, Start of the conference - Eva Bártová, Josef Lazar, Lecture Josef Lazar, Using optical directionality of fluorescent proteins in molecular probes. Overview of the activities of the Czech Biophysical Association (CBA), discussion and proposals for the next year, Members' meeting of the CBA.
   Thursday June 8, 2023, Invited lecture, Tomáš Polívka - Photoprotection in photosynthesis: How ultrafast energy transfer helps to survive under too much light; lectures of Radek Šachl, Jaroslav Malina, Vlastimil Tichý, Radka Vozárová, Josef Houser and Dita Strachotová.
    Friday June 9, 2023, Poster Session (short presentations, evaluation of posters), Keynote lecture: Jeanette Carey, Princeton, USA; invited lecture: Jaroslaw Jacak, Linz, Chasing the individual Extracellular Vesicles. Panel Discussion - Biophysics in the Czech Republic.
Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: June 7-9, 2023, Theatre Hall of the Academic Chateau in New Castle 
Responsible unit: Working Group, director of the Institute
Indicator(s)/Targets: The first conference of the CBA involved several highly valuable presentations, a number of scientific contributions and posters. The posters have been evaluated and the first 3 contributions have been awarded. The total number of participants was 43, from 21 from abroad. The ratio R1/R2/R3/R4 was approximately 50/20/20/10%. In the presentations, new techniques for cell and molecular biology were discussed. Measurable indicator: number of participants/lecture hall capacity was around 50%. Action 10.20 will have high priority for institutional strategy as well as for HRS4R.
Number of participants: 43
Current status: Completed

Sub-Action 10.21
Title: Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress (here) Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: May 25, 2022, Lecture Hall of the Institute
Lecturer: Dr. Jan Benada
Responsible unit: Working Group, director of the Institute
Indicator(s)/Targets: Dr. Jan Benada from Laboratory of Prof. Claus Sorensen, Biotech Research and Innovative Centre, University of Copenhagen, Denmark, presented us the lecture. The ratio R1/R2/R3/R4 was 11/13/3/5.  In the presentation, new results from cancer biology will be discussed. Measurable indicator (number of present participants from the Institute/number of scientists of the Institute working in the field) approx. 60%. Action 10.21 had high priority for institutional strategy as well as for HRS4R.
Number of participants: 35
Current status: Completed

Sub-Action 10.22
Title: Director's Collegium
Meeting program: 1) Presentation of the news by the director or the Institute Eva Bártová, 2) Presentation of project calls by the Project Manager, Ing. Šárka Dvořáková, 3) Information about Ph.D. studies by the member of the Council of the Academy of Sciences, prof. Jan Vondráček, 4) Presentations of the results of projects supported by the "Internal Support of Research Program": Mgr. Jiřina Procházková, RNDr. Lenka Šindlerová, Mgr. Jana Krejčí, Mgr. Martin Stojaspal, Ing. Václav Bačovský. The members of the Collegium selected the best results presented by Mgr. Jiřina Procházková. The director of the Institute awarded a prize to her including some financial reward.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: June 21, 2023
Responsible unit: Steering Commitee, Director of the Institute
Indicator(s)/Targets: The Collegium consists of all department leaders as well as management representatives and represents an important body for exchange of information and preliminary discussion of current problem, which can be solved at the Board of the Institute. The total number of participants was 22 from 27 members. Measurable indicator: 22/27=81%. Action 10.22 had high priority for both institutional strategy and for HRS4R.
Number of participants: 22
Current status: Completed

Sub-Action 10.23
Title: Post-SYMBIT seminar
Detailed information: The seminar is organized within sustainability period of the project "Structural gymnastics of nucleic acids: from molecular principles through biological functions to therapeutic targets" This seminar involved the following lectures: J.L. Mergny: Duplex-Quadruplex Competition, V. Brázda: What do G-quadruplexes in Viral Genomes Tell US?
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: July 12, 2023, Lecture Hall of the Institute
Organizer: Miroslav Fojta
Responsible unit: Working Group, Steering Committee, director of the Institute
Indicator(s)/Targets: In the seminar 31 scientists and students from Brno region, mainly from the Institute of Biophysics CAS took part. The ratio R1/R2/R3/R4 was 8/4/13/4 and 2 students took part in the meeting. Measurable indicator (number of present participants from the Institute/number of scientists and students from all Departments participating in the SYMBIT project) approximately 65%. Action 10.23 have had high priority for institutional strategy as well as for HRS4R.
Number of participants: 31
Current status: Completed

Sub-Action 10.24
Title: Conference on "Plant Chromosome Biology", Cytogenetics meeting 2023 (Programme and Photos 1, 2, 3)
Introduction: The conference brought together researchers investigating all aspects of plant genomes. Considering the ongoing progress in the field of chromosome biology, the focus of this meeting was the structure of plant chromosomes and genome dynamics in the light of epigenomic stability. Like the years before, the meeting provided excellent opportunities to stimulate scientific discussions regarding chromosome engineering, advanced chromosome biology and plant breeding. The program addressed a broad spectrum of fundamental and applied aspects of these topics. Confirmed speakers: Jiří Macas, Tony Heitkam, Holger Puchta, Jaroslav Doležel, Andreas Houben
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: September 11-13, 2023, Brno
Responsible unit: Steering Commitee, Director of the Institute
Indicator(s)/Targets: The meeting was held in Brno, Czech Republic and organized by Dr. Roman Hobza from the Department of Plant Developmental Genetics, Institute of Biophysics of the Czech Academy of Sciences and was supported by the Society for Plant Breeding e.V. (GPZ), section “Cytogenetic and Chromosome Analysis”.  Action 10.24 had high priority for both institutional strategy and for HRS4R.
Number of participants: 110
Current status: Completed

Sub-Action 10.25
Title: Post-SYMBIT seminar (photo see here)
Detailed information: The seminar is organized within sustainability period of the project "Structural gymnastics of nucleic acids: from molecular principles through biological functions to therapeutic targets" This seminar involved the following lectures: V. Vavrova: Systematic study of thermal and isothermal differential spectra of four-stranded structures of nucleic acids, D. Dobrovodsky: Electrochemical probes as tools for the study of DNA structure.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: September 14, 2023, Lecture Hall of the Institute
Organizer: Miroslav Fojta
Responsible unit: Working Group, Steering Committee, director of the Institute
Indicator(s)/Targets: In the seminar 23 scientists and students from Brno region, mainly from the Institute of Biophysics CAS took part. The ratio R1/R2/R3/R4 was 7/5/6/3 and 2 students took part in the meeting. Measurable indicator (number of present participants from the Institute/number of scientists and students from all Departments participating in the SYMBIT project) approximately 45%. Action 10.25 have had high priority for institutional strategy as well as for HRS4R.
Number of participants: 23
Current status: Completed

Sub-Action 10.26
Title: 23rd Joint Meeting of Biophysical Chemists and Electrochemists (invitation, see picture)
The main topics in the scope of the meeting are:  Electrochemistry and biophysics of molecular (redox) interactions, Biosensing and electroanalysis, Single-molecule spectroscopy and nanoscopy, Molecular electrochemistry and biocatalysis, In-silico calculations of molecular interactions, Biointerfaces
Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: November 1-2, 2023, J. Heyrovský Institute of Physical Chemistry of the CAS, v. v. i. Dolejškova 2155/3, 182 23 Prague 8, Czech Republic
Responsible unit: Working Group, director of the Institute
Indicator(s)/Targets: The best students have been awarded by the prize of Emil Paleček. Measurable indicator: number of participants/lecture hall capacity was around 80%. Action 10.26 had high priority for institutional strategy as well as for HRS4R.
Number of participants: 62
Current status: Completed

Sub-Action 10.27
Title: IBP CAREER DAY: "Per Aspera ad Astra" (pictures can be seen here)
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Lecturers: Vladimíra Petráková, Martin Vita, Panagiotis Alexiou, Vratislav Košťál 
Timing: November 9, 2023, Lecture Hall of the Institute
Organizer: Hana Polášek-Sedláčková
Responsible unit: Working Group, director of the Institute
Indicator(s)/Targets: Young researchers of the Institute of Biophysics (IBP) of the Czech Academy of Sciences are inviting students and postdocs to IBP career day: Per Aspera Ad Astra focused on future career possibilities in the academic and industrial spheres. During the event, four outstanding scientists have shared stories of their scientific journeys and have lead popular round table discussions on various topics. Measurable indicator (number of participants/number of postdocs and PhD students at the Institute). The number of participants corresponded to the number of young researchers (approx 80%), R1/R2/R3/R4=19/11/0/1. Action 10.27 had high priority for institutional strategy as well as for HRS4R.
Number of participants: 50
Current status: Completed

Sub-Action 10.28
Title: Director's Collegium
Meeting program: 1) Awards of IBP - presentations and selection by the Collegium members, 2) R. Ulrich: Projects of the Czech national agency, 3) S. Dvorakova: Information about the state of projects at IBP, 4) S. Kozubek: Evaluation of IBP by national methodology and preparation of the next academic evaluation, 5) K. Soucek: New facility fo cell sorting, 6) P. Cembis: Information on covid testing at IBP.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: November 14, 2023
Responsible unit: Steering Commitee, Director of the Institute
Indicator(s)/Targets: The Collegium consists of all department leaders as well as management representatives and represents an important body for exchange of information and preliminary discussion of current problem, which can be solved at the Board of the Institute. The total number of participants was 27 from 31 members. Measurable indicator: 27/31=87%. Action 10.28 had high priority for both institutional strategy and for HRS4R.
Number of participants: 27, 2 guests
Current status: Completed

Sub-Action 10.29
Title: Post-SYMBIT seminar
Detailed information: The seminar is organized within sustainability period of the project "Structural gymnastics of nucleic acids: from molecular principles through biological functions to therapeutic targets" This seminar involved the following lectures: Jiří Fajkus: Telomerase RNA gene paralogs: the usual pathway to unusual plant telomeres, Petr Fajkus: GERONIMO: a tool for systematic retrieval of structural RNAs in a broad evolutionary context, Vratislav Peška: TeloBase: a community-curated database of telomere sequences across the tree of life.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: November 15, 2023, Lecture Hall of the Institute, 13 h
Organizer: Miroslav Fojta
Responsible unit: Working Group, Steering Committee, director of the Institute
Indicator(s)/Targets: In the seminar 25 scientists and students from Brno region, mainly from the Institute of Biophysics CAS took part. The ratio R1/R2/R3/R4 was 11/6/9/7. Measurable indicator (number of present participants from the Institute/number of scientists and students from all Departments participating in the SYMBIT project) approximately 50%. Action 10.29 have had high priority for institutional strategy as well as for HRS4R.
Number of participants: 25
Current status: Completed

Sub-Action 10.30
Title: Methodological seminar "Machines and Methods: Basics of Metacentrum hands-on
Detailed information: This course shows how to process and analyse sequencing data using MetaCentrum NGI. Participants have been introduced to the basic usage of MetaCentrum, e.g. how to log in to the frontend server, how to manipulate data properly, and how to start an interactive or batch job.
GAP Principles: (+/-) 7. Good practice in research a (+/-) 28. Career development
Timing: November 30, 2023, Lecture hall of the Institute
Responsible unit: Steering Commitee, Council of the Institute, Director of the Institute
Indicator(s)/Targets:  The methodological seminar was dedicated to all categories R1-R4: category/participants: R1/5, R2/3, R3/1, R4/2. Measurable indicator: 100%. Action 10.30 had high priority for both institutional strategy and for HRS4R. 
Number of participants form the Institute: 11
Current status: Completed

Report for 2022-2023
Title: Report about lectures provided by foreign scientists, director's collegia, meetings of researchers, meetings of WG and SC, meetings of parents in science in 2022-2023
Detailed information: In 2022, we organized 4 lectures by foreign scientists (K. Makova, H. Fulkova, P. Kumar, P. Kania), 3 Methodological Symposia (lecturers: Vaclav Brazda, Sona Legartova, Vaclav Bacovsky, Jana Krejci, Karel Soucek, Radek Fedr, Vladislaf Krzyzanek, Kamila Hrubanova, Ota Samek), 2 Director’s Collegia, a meeting to establish „Czech Biophysical Association“, one ISAB meeting, IBP Career Day (organized by Hana Polášek-Sedláčková) where a discussion on career possibilities has been arranged and International meeting on Extracellular Vesicles organized by L. Kubala. In addition meeting with parents in science have been organized during the Summer schools (Action 14).
    In 2023, 3 lectures were organized in the Institute (L. Čermák, J. Vorel and J. Benada); Meeting of the Czech Biophysical Association: "Focused on Microscopic and Biophysical Techniques" was organized in Nové Hrady including 11 top lectures and 18 posters (see Action 10.16). The Czech Biophysical Association has been founded on April 7, 2022 in order to provide information, arrange workshops and meetings in biophysics in the Czech Republic as well as keep the link to the international union for biophysics (IUPAB). The CBA was admitted to the Council of the Czech Scientific Associations on April 24, 2023. In 2023, 3 Director's Collegia have been organized with standard programs (see Sub-Action 10.16, 10.22 and 10.28).
    During the first period (2022-2023) we have organized 6 meetings of the Working Group and 3 meetings of Steering Committee (see web page for HR, implementation).
Timing: 2022-2023.
Responsible Unit: HR Award Team - Steering Commitee, Director
Responsible Sub-Group: Stanislav Kozubek, Martin Falk, Miroslav Fojta, Pavel Vacek
Indicator(s)/Targets:  Invitations and Minutes of these meetings have been archived and translated into English. Meetings are open for R1-R4 categories. The participation of scientists in these activities has been carefully checked. Measureable indicators: number of participants/number of available employes at given category (e.g. number of participants at the directors collegium/number of members of the collegium). In most cases, this indicator ranged between 60% and 100%. Action 10 has high priority for institutional strategy, average priority for HRS4R.
Current Status: Completed for 2022-2023; in order to achieve higher level of lectures and scientific meetings, the activity will be continued and extended in the next period.

Action 11. (text from the Action Plan)
Title: Increased PR activities
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: We are going to present research results in media and popular science journals (report will be given at the last quarter each year). Within PR activities we will also organize the IBP Open House Days (4. quarter, each year) . We will also introduce the Institute at the Science Fair (2. quarter, each year). Also, we will participate in Mendel Festival in Brno (3. quarter, each year). We will coordinate updating of the IBP website; improvements must be made in the English version (end of this year). PR activities will be mediated through public journals and social media annually (report will be given at the end of each year).
Responsible Unit: Steering Commitee, WG
Indicator(s)/Targets: The PR manager provides activities related to PR (“public relations”). These activities will lead to the promotion of IBP research and its reputation in the public eyes. Advertisement on the IBP web page, social media, including Facebook, and Twitter. PR activity will be open for all categories, including students of all degrees, and secondary school students. At this point, 10-12 researchers will be engaged to organize PR activities each year. The percentage of categories involved in this activity is the following: 40/30/20/10. We will address the following principles: 9, 22 and this activity will be directed to students of all categories and the public. Measurable indicator: number of researchers involved in PR activities (% from all researchers). Action 11. has high priority for HRS4R, average priority for institutional strategy.
Current Status: In progress
Remarks:

Sub-Action 11.1
Title: Spring Concert at the Institute of Biophysics (invitation)
Performing singers: 1. Jana Chaloupková (soprano), Marta Vašková (piano), both from Faculty of Medicine, Masaryk University (see picture)
2. DNA group (Vašek Brázda, Institute of Biophysics, CAS)
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: April 28, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets: This activity leads to the promotion of research and particularly IBP research to the public eyes showing that scientists are engaged also in cultural life. The action was open to all employees of IBP. Number of participants: 30. Measurable indicator: all interested employees took part at the concert (100%). Action 11.1 had high priority of HRS4R.
Current Status: completed

Sub-Action 11.2
Title: Regular information on Institutional events on Facebook (year 2022)
Responsible scientists: Eda Kejnovský, Vojtěch Hudzieczek
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing/Title:
December 20, 2022, As part of the pre-Christmas meeting of researchers, at which the past year is traditionally evaluated, the employees of the BFÚ were presented with awards for the most significant achievements related to research activity.
December 8, 2022, Department of Radiobiolgy and cell biology is looking after postdoc in the field of pland telomeres and telomerases.
December 6, 2022, Postdoctoral researcher in the field of cancer biology (Marek Mraz, CEITEC, MU)
December 6, 2022, A recipe for longevity. Václav Brázda is looking for ingredients in the Greenland shark genome
December 1, 2022, Behind the secret of the smallhead shark's longevity (movie premiere) IBP, Ostrava univerzity
December 2, 2022, GMO topic at ScienceCafe V. Bergougnoux, V. Hudzieczek, F. Rolland and M. Warzaczek)
November 17, 2022, GMO topic at ScienceCafe (Czech Liaison Office for Education and Research in Brussels), speaker V. Hudzieczek
November 16, 2022, Telomeres of different organisms, research results of the Deparment of molecular epigenetics
November 15, 2022, Czech Liaison Office for Education and Research in Brussels organizes discussion on GMO, climatechange etc.
November 10, 2022, New publications of R. Vlček and H. Ulbrechtová were prezented
November 4, 2022, The prizes for youg scientists and students were awarded by the director, Eva Bártová, based on ISAB evaluation
November 3, 2022, Prezentations from the Open Day (short video)
November 2, 2022, One of the most important project SYMBIT has been finished (31.10.2022)
Novemeber 1, 2022, Senior club at IBP organizes Meeting of senior scientists with young scientists) (3.11.2022)
October 27, 2022, Open Day at the Institute (in the frame of the Week of the Czech Academy of Sciences)
October 25, 2022, Autumn School of Electron Microsocpy 2022 (Institute of Scientific Instruments in collaboration with IBP)
October 20, 2022, Grand agency of the Czech republic opens call for evaluators of research projects
October 4, 2022, IBP career day: Per Aspera Ad Astra focused on future career possibilities in the academic and industrial spheres.
October 4, 2022, Nobel prize for paleogeneticist Svante Pääb
September 30, 2022, Today is a Night of Scientists at our institute - feel free to come, you can see our supermicroscopess,
September 23, 2022, "Telomeres and their neighbors" - paper from the Department of radiobiology and cell biology.
September 20, 2022, Institute is joining the action "Night of Scientists".
September 16, 2022, International workshop (29-30.9.2022) about bacterial extracellular vesicles is organized by the Department of biophysics of immune system.
September 9, 2022, Exhibition Centre, Science Fair 2022, Institute of Biophysics at stand no.3.
September 8, 2022, Information about "Junior Star 2022" projects
September 6, 2022, Information about the electrochemistry meeting organized jointly by IBP and Heyrovsky institute.
September 6, 2022, Information about the children group at the Institute "Elánek BFÚ"
September 5, 2022, Genetic engineering, Scientific Fair at the exhibition center in Brno (building A1)
September 2, 2022, A question: Are RNA modifications markers of damaged RNA or contribute to the repair of damaged DNA? Alena Kovaříková Svobodová and Eva Bártová
August 31, 2022, P. Vacek: Production of electricity from our photovoltaic power station (July)
August 22, 2022, The influence of radioactivity on the cells (Martin Falk)
August 15, 2022, Senior club at the Institute of Biophysics, CAS
August 8, 2022 The department of Molecular biophysics and pharmacology popularized their results 
August 1, 2022, P. Vacek: Production of electricity from our photovoltaic power station (July),
August 1, 2022, Information about the "Week of the Czech Academy of Sciences" (October 31, 2022 - November 6, 2022),
July 27, 2022, Information about HR Award,
July 25, 2022, Stand of the Institute of Biophysics, CAS at the Mendel Fair,
July 12, 2022, The Department of Cell Biology and Epigenetics is looking for a postdoctoral fellow.
June 30, 2022, P. Vacek: Production of electricity from our photovoltaic power station (June),
June 24, 2022, Department of structure and dynamics of nucleic acids described different types of connections between DNA ends,
June 21, 2022, President of the CAS, Prof. E. Zazimalova congratulates Prof. B. Vyskot and Prof. A. Lojek to their award of "Emeritus Researchers",
June 21, 2022, President of the CAS, Prof. E. Zazimalova congratulates Mgr. P. Fajkus to his Otto Wichterle award,
June 16, 2022, O. Wichterle prize awarded to P. Fajkus, 
June 16, 2022, Director of the Institute congratulates Mgr. P. Fajkus to his Otto Wichterle award,
June 16, 2022, Medal for PR awarded to E. Kejnovský and medal for merits of CAS awarded to S. Kozubek,
June 16, 2022, P. Vacek: Production of electricity from our photovoltaic power station,
June 10, 2022, Exhibition of photography from a light and electron microscope,
June 9, 2022, Junior Star project awarded to H. Polášek-Sedláčková,
June 8, 2022, E. Kejnovský: The origin of life (YOUTUBE),
June 7, 2022, Childrens Day was held on June 3, 2022,
June 7, 2022, E. Kejnovský: Are viruses alive? (YOUTUBE),
June 2, 2022, Our Institute at the Fair of Science (see Action 11.5),
May 26, 2022, Mayor of Brno - Žabovřesky, Lucie Pokorná, visited our Institute,
May 23, 2022, "Milestones of genetics" by E. Kejnovsky,
May 26, 2022, Fair of Science will start in a week,
May 20, 2022, Vanilin formula at 3D print,
May 18, 2022, DNA model from 3D printer,
May 13, 2022, Application Laboratory,
May 4, 2022, Summer school,
April 28, 2022, Sex determination in plants,
April 25, 2022, Guanin complexes in viruses,
April 19, 2022, Shark aging, Evaluation according to M17+ methodology,
April 15, 2022, up to March 29, 2022 Riding by bike to the workplace,
March 28, 2022, Conference on evaluation of science,
March 24, 2022, International Conference on Microscopy, Brno (information),
March 11, 2022, PhD position at IBP, March 8, 2022 Conference "The Biomania Student Scientific Meeting on Biotechnology,
March 8, 2022, PhD position in IBP,
March 7, 2022, Collection of donations for Ukraine,
March 7, 2022, G-quadruplexes in infection treatment,
February 28, 2022, Collection of donations for Ukraine,
February 2, 2022, Toxic concentration of metals in plants,
January 28, 2022, Announcement of the selection procedure for the post of director,
January 13, 2022, Evaluation of science - contribution in the Czech Journal of Physics,
January 4, 2022, Events of the last year.
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets: This activity leads to the popularisation of research and particularly IBP research to the public eyes showing the most interesting results of research as well as achievements of the Institute and its position among other research organisations. The action is open to the society interested in science. Number of contributions from the beginning of the year: 84 . Measurable indicator: number of likes = 240. Action 11.2 had high priority for HRS4R.
Current Status: in progress

Sub-Action 11.3
Title: Traditional activities: Open Day, Science Fair at Prague, Mendel Festival at Brno
Responsible scientists: Eda Kejnovský, Vojtěch Hudzieczek
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: November 2, 2022 - Open Day, June 2-4, 2022 Science Fair, July 23, 2022 Mende Festival
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets: These activities will lead to the promotion of IBP research and its reputation in the public eyes. These activities will be open for all categories, including students of all degrees, and secondary school students. At this point, 10-12 researchers will be engaged to organize PR activities each year. The percentage of categories involved in this activity is the following: 40/30/20/10. The activities will be directed to students of all categories and the public. Measurable indicator: % of researchers involved in PR activities (60% of all researchers). Action 11. has high priority for HRS4R, average priority for institutional strategy.
Current Status: In progress

Sub-Action 11.4
Title: Milestones of genetics (title page)
Publication "Milestones of genetics: from Mendel to the present time" (Academia 2022/5) provides comprehensive information about advances of genetics starting from J.G. Mendel who founded genetics by revolutionary discoveries in Brno monastery up to recent discoveries enabling targetted changes of genetic information at the level of organisms. 
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: May 1, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of readers about the immense importance of genetics and science. This activity is open to the public, including students of all degrees, and secondary school students. Action 11.4 has high priority for HRS4R, average priority for institutional strategy.
Current Status: Completed

Sub-Action 11.5
Title: Fair of Science 2022
Invitation: How does DNA structure affect cell function? How does modern microscopy work and what information does it provide us with? Why have we historically been involved in space research? What is genome editing and why has this technology changed the world? What are genetically modified plants for? And how these topics relate to the life and work of Johann Gregor Mendel? You will learn all this and much more when you visit the stand of the Institute of Biophysics of the CAS at the Science Fair, the largest popular science event in the Czech Republic. We are waiting for you at booth number 3, from Thursday 2.6. until Saturday 4.6., always between 10.-18. hour.
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: June 2, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. This activity is open to the public, including students and children. Measurable indicator: % of researchers involved in PR activities (10% of all researchers). Action 11.5 has high priority for HRS4R.

Sub-Action 11.6
Title: Mendel Festival - The stand of the Institute of Biophysics CAS
Detailed information:  CAS and our Institute participated in the Mendel Festival that incuded: round table "Ethical questions in genetics" (Eva Zažímalová, Tomáš Machula, Jan Konvalinka, Dominik Opatrný, Marek Svoboda, Hynek Latta. Moderují Věra Franková a Milan Macek jr.), discussion with the author of The Glass Room and Mendel's Dwarf (Simon Mawer), history of the old Brno (Marek Peška, Lenka Sedláčková, Petr Vachůt), Genetic genealogy or what is written about our ancestors in our DNA (Martin Kotačka), Mendel University in Brno - about Mendel life, how to live a longer and healthier life? (discussion with Petr Smejkal and Petr Ludwig). The festival ended with a performance by Ewa Farná and fireworks.
The stand of the Institute of Biophysics at the Mendel Festival on Mendel Square in Brno was visited by hundreds of people interested in science, especially children and students. We were also honored with a visit by the Minister of Health, Prof. Vlastimil Válek (see here), vice-rector of MU prof. Šárka Pospíšilová (see here) and of course our director, doc. Eva Bártová (see here). Despite the hot weather, the interested parties enjoyed, for example, looking into our microscopes.
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: July 20-24, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targeted general awareness of public about the importance of science. This activity was open to the public, including students and children. Measurable indicator: % of researchers involved in PR activities (10% of all researchers). Action 11.6 had high priority for HRS4R.
Current Status: Completed

Sub-Action 11.7
Title: The Secrets of Genes (series of youtube lectures covering genetics and evolution from the origin of life on the Earth to human genome).
Detailed information:  New lectures are published on each Wednesday, Chapter 1: Are viruses alive?, Chapter 2: The origin of life on the earth, Chapter 3: Hell or Heaven: The Origin of Life on the Ocean Floor, Chapter 4: Did the life come from outer space? The theory of panspermia, Chapter 5: The oldest life on Earth: Stromatolites, Chapter 6: How do genes work?, Chapter 7: The ancient world of RNA molecules, Chapter 8: Genetic Code. The latest chapter: https://www.youtube.com/watch?v=SvhDj02KdhY
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: starting on January, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. The number of Youtube video views is up to 350 (for the first chapter). Action 11.7 had high priority for HRS4R.
Current Status: In Progress

Sub-Action 11.8
Title: New achievements in the research of anti-cancer drugs (Facebook, Twitter, Web).
Detailed information:  Employees of the Department of Molecular Biophysics and Pharmacology (DMBP) of the Institute of Biophysics of the Czech Academy of Sciences are investigating the possibilities of better use of anti-cancer drugs. Their research is focused on cytostatics containing metal atoms, the so-called metallopharmaceuticals. An example of a promising photoactivatable cytostatic recently tested in the laboratories of the DMBP of is an iridium complex combined with a coumarin molecule, which after photoactivation is able to effectively destroy both stem cells and other rapidly multiplying tumor cells, especially prostate tumors. It is the second most common type of cancer in men worldwide (https://onlinelibrary.wiley.com/doi/10.1002/anie.201901268).
Responsible scientists: Viktor Brabec
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: August 3, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Action 11.8 has high priority for HRS4R.
Current Status: Completed

Sub-Action 11.9
Title: Night of Scientists
Detailed information: Institute of Biophysics, CAS was involved in the "Night of Scientists" organized in the Czech Republic. The topic of this year was "microscopy". Scientists of the Institute introduced the microscopic techniques to the visitors (mainly children or young visitors).
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: September 30, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Measurable indicator: % of researchers involved in PR activities (60% of all researchers). Action 11.9 had high priority for HRS4R.
Current Status: Completed

Sub-Action 11.10
Title: How "radioactivity" damages our cells, how cells protect themselves from this damage, and how we can study these processes (Facebook, Twitter, Web).
Detailed information:  What connects the Jachymov spa, the planned flight to Mars and space research in general, the current occupation of Ukraine by Russia, the transformation of healthy cells into cancer cells and, conversely, the effective treatment of cancer patients, diagnostic imaging in medicine, relatively ecological energy sources, but also tragic nuclear power plant accidents, threatening terrorist attacks using the so-called dirty bomb, the largest project in the history of science (the Manhattan Project), nuclear weapons and the atomic bombing of the Japanese cities of Hiroshima and Nagasaki, poorly built houses on "radon bedrock", research into fundamental life processes in cells, the natural evolution of organisms, a lot other important phenomena and research of the Department of Cell Biology and Radiobiology of the Institute of Biophysics of the Czech Academy of Sciences? This is ionizing radiation and its ubiquitous effect on living organisms, including humans. If you are interested in these topics, find it difficult to navigate media reports that usually hyperbolize anything related to radioactivity, need a better understanding of radiobiological units and the relationship between the type of ionizing radiation, its dose and health risk, or are professionals and just want to learn more about our research and the current state of knowledge in the field of radiobiology and radiation biophysics, then follow this new series of contributions, in which we will gradually address interesting radiobiological problems and events in more detail. The article below provides an introduction to this series.
Responsible scientists: Martin Falk
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: August 26, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Action 11.10 has high priority for HRS4R.
Current Status: In Progress

Sub-Action 11.11
Title: Open Day
Detailed information: Institute of Biophysics, CAS was involved in the "Week of Czech Academy of Sciences" organized by the Czech Academy of Sciences. Scientists of the Institute prezented lectures and showed laboratories and particularly devices (e.g. microscopes) to interested students.
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: November 2, 2022, beginning at 9 h
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Measurable indicator: % of researchers involved in PR activities (90% of all researchers). Action 11.11 had high priority for HRS4R.
Current Status: Completed

Sub-Action 11.12
Title:  Project "Structural gymnastics of nucleic acids: from molecular principles through biological functions to therapeutic targets" is finished (Facebook, Twitter, Web).
Detailed information:  As of October 31, 2022, the almost six-year OP VVV financing period of the SYMBIT project expired (details about the project here https://www.ibp.cz/opvvv/symbit/). The project, based on the collaboration of experts in the field of structure and interactions of nucleic acids, led by the renowned foreign scientist Jean-Louis Mergny, produced a number of original results published in more than 150 peer-reviewed articles and in a number of other communications. New knowledge about the so-called non-canonical structures of DNA and RNA, their stability and dynamics, as well as their interactions with specific ligands - potential drugs and their recognition by proteins with known regulatory roles in important biological processes have been obtained. Using experimental and bioinformatics procedures, the occurrence of sequences with the potential to create non-canonical structures in the genomes of various organisms was mapped and new knowledge about their evolution was obtained. In parallel with these studies, new methods of studying the structure of DNA and RNA were developed, including computational methods, bioinformatics tools and experimental techniques based on nuclear magnetic resonance or electrochemistry. The financing of the project made it possible to establish new foreign collaborations and for young scientists from BFÚ (doctoral students and postdocs) to complete internships abroad, where they gained valuable international experience. A series of regular seminars contributed to scientific communication within the project and externally. The activities of the SYMBIT project will be further developed within the five-year sustainability period of the project and in subsequent scientific and educational projects.
Responsible scientists: Mirek Fojta
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: November 1, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Measurable indicator: % of researchers involved in PR activities (40% of all researchers). Action 11.12 has high priority for HRS4R.
Current Status: Completed

Report for 2022
Title: Report on increased PR activities in 2022
Detailed information: We have presented research results in media and our web pages (series on „how radioactivity damages our cells“, information about the project „Structural gymnastics of nucleic acids“, new achievements in the research of anti-cancer drugs). Regular information has been presented at Facebook (at least 75 contributions in 2022 and 75 contributions so far in 2023), Twitter or Youtube (series of lectures covering genetics and evolution). We also regularly organize the IBP Open Days, Spring Concert, Night of Scientists as well as we take part in the Science Fair and Mendel Festival in Brno (both in 2022 and 2023. We updated some parts of the IBP website (further improvements are needed).
Timing: report for 2022-2023.
Responsible Unit:  Steering Commitee, Working Group, Eduard Kejnovský
Indicator(s)/Targets:  Eduard Kejnovský together with other scientists provided activities related to PR („public relations“). PR activities consisted of contributions on the IBP web page, social media, including Facebook, and Twitter, participation at Open Days, Night of Scientists, Science Fair or organizing Spring Concert and have lead to the promotion of IBP research and its reputation in the public eyes. PR activities were open for all R1-R4 categories, including students of all degrees, and secondary school students. The percentage of categories involved in this activities corresponded  approximately to the plan (40/30/20/10%). We have addressed the principles: 9, 22 and this activity has been directed to students of all categories and the public. Measurable indicator: number of researchers involved in PR activities (% from all researchers): approximately 20-90%. Action 11. has high priority for HRS4R, average priority for institutional strategy.
Current Status: Completed for 2022-2023, the activity will be continued with some improvements.

Sub-Action 11.13
Title: Regular information on genes "The Secrets of Genes - from the Origin of Life to the Human Genome" (Youtube, in Czech language), see the advertisement in the journal Vesmir (here).
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing/Title:

1. Definition of life: Are viruses alive? (1/6/2022)
2. The origin of life on Earth (8.6.2022)
3. Hell or Paradise: The Origin of Life on the Ocean Floor (6/15/2022)
4. Did life come from outer space? Panspermia theory (6/22/2022)¨
5. The oldest life on Earth: Stromatolites (6/29/2022)
6. How do genes work? (7/6/2022)
7. The ancient world of RNA molecules (7/13/2022)
8. Genetic code (20.7.2022)
9. Why is hereditary information stored in DNA? (27/07/2022)
10. Silicon-Based Life (3/8/2022)
11. The first genome: From RNA to DNA (17.8.2022)
12. Living minimum of bacteria (24.8.2022)
13. Artificial life (31.8.2022)
14. How does DNA fit into a cell? (7/9/2022)
15. How big are genomes? (14/09/2022)
16. Major leaps in evolution (September 21, 2022)
17. Genomes and the origin of sexuality (September 28, 2022)
18. Rises and falls of genomes (5/10/2022)
19. Genome Landscape (12/10/2022)
20. Jumping genes – genomic parasites? (19/10/2022)
21. Jumping genes in our brain (26.10.2022)
22. Jumping genes as helpers (11/2/2022)
23. What do genes look like? (9/11/2022)
24. How do genes change? (11/16/2022)
25. Will men become extinct? Answer geneticist (23/11/2022)
26. GMOs: Threat or Hope? (30/11/2022)
27. What is promiscuous DNA? (7/12/2022)
28. Do genes travel between organizations? (14/12/2022)
29. Evolution of man (21.12.2022)
30. Evolution of man, genus Homo (28.12.2022)
31. Are Neanderthals our ancestors? (4/1/2023)
32. What can we read from human DNA? (11/1/2023)
33. Children on order (January 18, 2023)
34. I want to know my genome (25.1.2023)
35. Microbiome – a new organ (February 1, 2023)
36. Man as an ecosystem (2/8/2023)
37. Viruses and the Web of Life (2/15/2023)
38. Viruses on the edge of life (2/22/2023)
39. Evolutionary thought (1.3.2023)
40. Genes or education? (15/03/2023)
41. DNA as a window into the past (22.3.2023)
42. DNA as a window to the future (4/5/2023)
43. Genetic deserts (4/12/2023)
44. Genomic obesity (19.4.20203)
45. Genome of man, chimpanzee and Neanderthal (26/04/2023)
46. ​​Humanity Gene (3/5/2023)
47. Epigenetics (17.5.2023)
48. Genetic dactyloscopy (24/05/2023)
49. Something for something (31.5.2023)
50. Benefits of hereditary diseases (7/6/2023)

51. The lock and key principle (6/21/2023)
52. Examples of the principle of complementarity (6/28/2023)
53. Cells (7/12/2023)
54. Chromosomes (19/7/2023)
55. Milestones of genetics 1 (26/7/2023)
56. Milestones of genetics 2 (9/8/2023)
57. Milestones of genetics 3 (16/08/2023)
58. Milestones of genetics 4 (23/8/2023)
59. Milestones of genetics 5 (6/9/2023)

Responsible Unit: Eduard Kejnovský, Steering Commitee, WG, director of the Institute
Indicator(s)/Targets: This activity represents the popularisation of research to the public eyes showing the most interesting results of research. The action is open to the society interested in science. Number of contributions: 50 . Measurable indicator: numbere of views = 9700. Action 11.13 had high priority for HRS4R.
Current Status: In progress

Sub-Action 11.14
Title: Mysterious underwater world through the eyes of creative photography (here)
Detailed information: author's exhibition by Michal Štros
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: April 4, 2023 - May 5, 2023
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Measurable indicator: % of researchers involved in PR activities (80% of all researchers). Action 11.14 had high priority for HRS4R.
Current Status: Completed

Sub-Action 11.15
Title: Fair of Science 2023 (photo with the President of the Czech Academy of Sciences see here)
Invitation: In the Fair of Science participated all institutest of the Czech Academy of Sciences. Institute of Biophysics of the Academy of Sciences of the Czech Republic fucused attention to the broad field of questions from research into the origin of life to genetic engineering. How does the structure of DNA affect the functioning of cells? How does modern microscopy work and what information does it convey to us? Why have we historically participated in space exploration? What is genome editing and why has this technology changed the world? What are genetically modified plants for? You will learn all this and much more when you visit our stand at the Science Fair, the largest popular science event in the Czech Republic. Institute of Biophysics, that is a rich history and modern science!
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: June 8-10, 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. This activity is open to the public, including students and children. Measurable indicator: % of researchers involved in PR activities (60% of all researchers). Action 11.15 has high priority for HRS4R.

Sub-Action 11.16
Title: Variability of Inverted Repeats in All Available Genomes of Bacteria (Facebook, Twitter, Web).
Detailed information:  Important biological roles of cruciform structures formed by inverted repeats (IRs) have been demonstrated in diverse organisms, including humans. Using Palindrome analyser, we analyzed IRs in all accessible bacterial genome sequences to determine their frequencies, lengths, and localizations. IR sequences were identified in all species, but their frequencies differed significantly across various evolutionary groups. This first comprehensive analysis of IRs in all available bacterial genomes demonstrates their genomic ubiquity, nonrandom distribution, and enrichment in genomic regulatory regions.
Responsible scientists: Václav Brázda
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: June 26, 2023
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Action 11.16 has high priority for HRS4R.
Current Status: Completed

Sub-Action 11.17
Title: Banning plant DNA editing is evolutionary suicide (Facebook, Twitter, Web).
Detailed information:  What currently threatens the fertility of European fields the most? Climate change of course. At the same time, the debate about its existence is completely unnecessary. Everything is always changing, that is the essence of evolution. And we have to adapt. Humanity sometimes thinks that by some miracle it can preserve the current state of things that we see around us right now. But we will never succeed. Nature has tremendous power and is always moving somewhere. We don't know where, but we have to try to adapt. Now it might be drought, a change in temperature or the structure of the pests that are present here. The conditions for crops in a given place are constantly changing and we have to respond to this either by starting to grow completely different plants, or by preserving the existing ones and breeding them to new conditions. That's actually what we've always done. By the way, the new conditions include, for example, an increase in the human population. Therefore, we had to start breeding crops for greater yield. We've always adapted and there's no reason we shouldn't continue to do so.
Responsible scientists: Roman Hobza
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: June 29, 2023
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Action 11.17 has high priority for HRS4R.
Current Status: Completed

Sub-Action 11.18
Title: G-quadruplexses in the evolution of hepatitis B virus (Facebook, Twitter, Web).
Detailed information:  Hepatitis B virus (HBV) is one of the most dangerous human pathogenic viruses found in all corners of the world. Recent sequencing of ancient HBV viruses revealed that these viruses have accompanied humanity for several millenia. As G-quadruplexes are considered to be potential therapeutic targets in virology, we examined G-quadruplex-forming sequences (PQS) in modern and ancient HBV genomes. The results, which constitute the first paleogenomics analysis of G4 propensity, are in agreement with our hypothesis that, for viruses causing chronic infections, their PQS frequencies tend to converge evolutionarily with those of their hosts, as a kind of ‘genetic camouflage’ to both hijack host cell transcriptional regulatory systems and to avoid recognition as foreign material.
Responsible scientists: Václav Brázda, Jean-Louis Mergny
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: July 4, 2023
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Action 11.18 has high priority for HRS4R.
Current Status: Completed

Sub-Action 11.19
Title: Mendel Festival 2023  (Invitation)
Detailed information: The magical combination of quality music, educational activities and popular-scientific lectures in the setting of the Augustinian Abbey on Mendlová náměstí in Brno brings the right mix of culture and knowledge every year. Thanks to this connection, the festival has a unique atmosphere and has become one of the most visited events in the South Moravian region.
       The Mendel festival is traditionally opened by a holy mass in the Basilica of the Assumption of the Virgin Mary on Sunday, July 16, from 11 a.m. Mass will be celebrated by Father Marek Orcho Vácha. The festival will then offer a number of interesting events throughout the following week, which we present on the Program at partners page and will culminate with the Saturday program in the abbey garden, which starts from 2 p.m.
       In 2023, the Czech Academy of Sciences and particularly our Institute participated in the Mendel Festival that incuded: Music program - Saturday Lineup (music bands "Poletíme?", "Fanfare Ciocarlia (Ro)" and "Gipsy Kings (Fr)".
       Lectures in Mendel Green House (Eduard Kejnovský from our Institute: "Secrets of genes - from the origin of life to the human genome" (see pictures), Dana Fialová and Šárka Pospíšilová (Masaryk University): "New insights into Mendelian traits read from the genome – eye color, tastes, smoking tendencies, etc", Michaela Nekardová (Society for Genetic Genealogy): "Genetic genealogy" and other lecturers).
       Interactive entertainment program for families with children at various sites (Institute of Biophysics, Academy of Sciences of the Czech Republic - World under the microscope, Mendel museum - The world under microscope, Stand of the Statutory City of Brno with a crocodile, Jiří Mahen Library, and other), tours (Tour of the Mendel museum, Tours of the Old Brno Abbey Museum, Starobrno Brewery – guided tours of the brewery,  Tour of the Mendelianum).
Responsible scientists from Institute of Biophysics: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: July 21-22, 2023
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targeted general awareness of public about the importance of science. This activity was open to the public, including students and children. Measurable indicator: % of researchers involved in PR activities (80% of all researchers). Action 11.19 had high priority for HRS4R.
Current Status: Completed

Sub-Action 11.20
Title: Regular information on Institutional events on Facebook (year 2023)
Responsible scientists: Eda Kejnovský, Vojtěch Hudzieczek
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing/Title:
December 5, 2023, Electrochemical properties of an orange pigment Sudan I has been studied by the Department of biophysical chemistry and molecular oncology
December 4, 2023, New grants awarded by the Czech grant agency - 5 projects will be solved at IBP
November 27, 2023, Research of revmatoid arthritis at IBP - a new breakthrough
November 17, 2023, Department of the biophysics of immune system published a new paper on adenyl cyclase pathway
November 15, 2023 Information about Senior Day
November 15, 2023, Information about workshop on microscopy Leica STELLARIS
November 11, 2023, Eduard Kejnovsky: About Darwin and Mendel in a paper published in VESMIR
November 10, 2023, IBP Career Day
November 6, 2023, Two years from the instalation of photovoltaic station at IBP
November 5, 2023, IBP awarded the price of Emil Paleček to Ravery Jovinar Sebuyoya
November 3, 2023, Meeting at J. Heyrovsky Institute with participation of scientists from IBP
October 6, 2023, Night of scientists in Brno
October 6, 2023, Nobel prize for peace has been awarded to Narges Mohammadiova.
October 5, 2023, Nobel prize for literature has been awarded to Jon Fosse.
October 4, 2023,  Nobel prizes for chemistry have been awarded to Moungi Bawendi, Louis Brus and Alexej Jekimov for research of quantum dots.
October 3, 2023, Nobel prizes for physics have been awarded to Pierre Agostini, Ferenc Krausz and Anne L'Huillierová for the research of electrons in atoms and molecules.
October 2, 2023,  Nobel prize for physiology and medicine has been awarded to Katalin Kariko and Drew Weissman for the development of mRNA vaccines against covid-19.
October 2, 2023 A new "Radiobiology textbook" with co-author Martin Falk from our Institute has been published.
September 27, 2023, EMBO course on academic writing - graphics in scientific publications.
September 27, 2023, IBP career day: Per Aspera Ad Astra 2023.
September 25, 2023, One of the research directions of our Institute - Epigenetics - is prezented.
September 22, 2023, Information about the comming "Night of Scientists 2023" with participation of our Institute.
September 21, 2023, "Czech Society for Extracelluolar Vesicles" has been founded in August 2023 with Kristýna Turková and Gabriela Ambrožová from our Institute as founding members.
September 20, 2023, Information about the conference on "Functional Organization of the Cell Nucleus" will take place in Prague on October 16, 2023 with participation of our Institute.
September 14, 2023, Assoc. Prof. Eduard Kejnovsky reached 60 contributions to the series on "Secrets of Genes"
September 11, 2023, Plant Chromosome Biology: Cytogenetics meeting 2023 at Brno under the patronage of the Institute of Biophysics (several contributions).
September 8, 2023, Dr. Hana Polášek-Sedláčková prezented a lecture on Eucaryotic DNA Replication and Genome Maingenance at Cold Spring Harbor conference.
September 5, 2023, Assoc. Prof. Eduard Kejnovsky: Milestones of genetics 5.
September 5, 2023, Science and Technology Festival 2023 at Brno exhibition areal with participation of our Institute (several contributions).
September 4, 2023, Podcast of Václav Brázda on the recipe for longevity.
August 28, 2023, The 49th year of the conference "Earth Breadwinner" in České Budějovice, has brought many interesting discussions. For example, the debate on the topic "New genomic breeding techniques: The path to sustainable food production?" Minister of Agriculture Marek Výborný and MEP Michaela Šojdrová, as well as representative of the Institute of Biophysics of the Academy of Sciences of the Czech Republic Vojta Hudzieczek spoke in the panel discussion.
August 22, 2023, The Institute of Biophysics will hold a traditional volleyball tournament.
August 16, 2023, A summer school of biophysics for children started at our Institute.
August 15, 2023, The department of Roman Hobza is one of the partnera of OP JAK project "New knowledge for plants of new generation" which has been granted by the Ministry of Education.
August 15, 2023, Assoc. Prof. Eduard Kejnovsky: Milestones of genetics 3.
August 14, 2023, A group of plant scientists from CEITEC Masaryk University and the Institute of Biophysics of the Czech Academy of Sciences (CAS) led by Jiri Fajkus, Petr Fajkus and Vratislav Peska made a fascinating discovery about plant DNA and how evolution has shaped plant telomeres.
August 8, 2023, Assoc. Prof. Eduard Kejnovsky from our Institute was awarded for his PR activites by the medal of Vojtěch Náprstek from the Czech Academy of Science.
August 1, 2023, The production of our FVE in July 2023 is approximately 20 MWh.
July 22, 2023, Mendel festival 2023 with the stand of our Institute.
July 13, 2023, Information about the Summer school in the Institute for children.
July 12, 2023, Invitation to the Summer Science Camp organized by the Czech Academy of Scinces in April 2023 for teachers of basic schools.
July 4, 2023, Václav Brázda, Jean-Louis Mergny and other authors published the first paleogenomic analysis in Nucleic Acid Research: "G-quadruplexes in the evolution of hepatitis B virus"
July 1, 2023, Energy produced by the Fotovolaic power station in the Institute.
June 29, 2023,  Roman Hobza has published in the attachement of "Hospodařské noviny" the following considerations: The problem of nutrition in the next years.
June 27, 2023, A new study written by Martin Bartas and Václav Brázda on specific DNA structures (palindroms) in bacteria  has been published in the famous journal "Microbiology spectrum".
June 27, 2023, Invitation to the Mendel Science Festival, stand of our Institute.
June 24, 2023, Collegium of the Institute awarded financial support to Jiřina Procházková, the Department of Cytokinetics, to solve the project on "Profiling sfingolipids on the surface of tumour cells".
June 21, 2023, Alena Kovaříková and Lenka Stixová published a paper explaining function of modified RNA in DNA repar.
June 15, 2023, A new site for lab meetings has been arranged in the garden of the Institute.
June 13, 2023, Czech Biophysical Association organized conference "Focus on microscopic and biophysical techniques" on 7-9.6.2023 in Nové Hrady. The conference was visited by 14 students from Princeton University, USA.
June 12, 2023 Academy of Sciences does not agree with the reduction of the budget for the next years.
June 10, 2023 Fair of Science - visit of the Ministrer for Science, Helena Langšádlová to the stands of academic institutes.
June 9, 2023, Secrets of sharks and its DNA, invitation to the stand of our Institute by Václav Brázda.
June 9, 2023, Fair of Science, stand of our Institute - secrets of human body.
June 8, 2023 Fair of Science, stand of our Institute - visit of the Chairman of the CAS, Eva Zažímalová and Minister for Science, Helena Langšádlová.
June 6, 2023, Invitation to PR activities such as Fair of Science, Mendel Festival of Science, Summer School of Biophysics.
June 6, 2023, Children's Day in the Institute
June 2, 2023,  Invitation to the Children's Day
June 1, 2023,  Invitation to the Fair of Science, stand of our Institute.
May 30, 2023, The Laboratory of Cell Biophysics offers a wide spectrum of microscopic analyses.
May 28, 2023, Fotovoltaic electric power station of the Institute generates energy.
May 25, 2023, The garden of the Institute of Biophysics, CAS, reveals its secrets.
May 23, 2023, An Agreement on collaboration between the Institute of Biophysics, CAS and Faculty Hospital St. Anne in Brno has been signed.
May 17, 2023, Scientists from our Institute and from CEITEC about bumble-beew in TV.
May 15, 2023, The best scientists in the field of chemistry - among 50 the best scientists belong Jiří Šponer, Viktor Brabec, Emil Paleček (in memmorial), Miroslav Fojta and Jana Kašpárková from our Institute.
May 12, 2023, Official agreement on collaboration has been signed between our Institute and the Institute of Chemical Processes of the Italian National Council.
May 12, 2023, Invitation to the Fair of Science, where scientists from the Institute also take part.
May 11, 2023, Chairman of the Czech Academy of Sciences visited the Institute of Biophysics, CAS, visited Junior Star laboratory, Application laboratory and discussed with young scientists.
May 7, 2023, Research activities of the Institute of Biophysics, CAS: Investigations of the structure, function and dynamics of biological systems using biophysical methods.
May 5, 2023, Invitation to the Children Day in the Institute of Biophysics, CAS
May 4, 2023, Invitation to the conference "Plant Chromosome Biology: Cytogenetics meeting 2023" from September 11-13, 2023 in Brno.
April 25, 2023, Lecture of Eduard Kejnovský "Secrets of Genes - from the Origin of Life to the Human Genome" (Observatory Brno).
April 24, 2023, Petra Školáková, Michaela Vorlíčková and other authors published in Nucleic Acid Research the article "DNA i-motif formation at neutral pH is driven by kinetic partitioning" about structure of DNA.
April 21, 2023, Eduard Kejnovký: "The life of jumping genes" (https://gacr.cz/zajimave-poznatky-ze-zivota-skakajicich-genu/)
April 20, 2023, Lenka Šindlerová from the Department of Biophysics of Immune System explained the influence of cyanobacteria on our immune systemin the presentation: "Cyanobacrerial water bloom"
April 19, 2023, Lecture of Jan Benada, Univ of Copenhagen: "Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress"
April 17, 2023, In the Institute of Biophysics, CAS, there several shared laboratories with regional or CR significance (Laboratory for Cell Biophysics, Virus Laboratory, Quantitative PCR techniques, Computer Graphics, Gamma-Rays Laboratory, Laboratory for Embryonal Stem Cells, GMO Laboratory, Green House, Application Laboratory, Laboratory of Biophysical Methods, Mouse Breeding Facility).
Apri 14, 2023, "Water and electrochemistry" by Martin Pivokonský from the Institute of Hydrodynamics.
April 14, 2023, An interesting paper of Jana Krejčí on "110 μm thin endo-microscope for deep-brain in vivo observations of neuronal connectivity, activity and blood flow dynamics" (collaboration with ISI CAS).
April 6, 2023, Happy Easter wishes the Institute of Biophysics.
April 5, 2023, Genetics and evolution - youtube lecture of Eduard Kejnovský.
April 4, 2023, Searching for the lost time. Outstanding Czech scientist, Antonín Holý, developed medicine for HIV, hepatitis of type B a further virus diseases.
April 4, 2023 Photogalery on underwater world has been shown in Academia cafe.
April 4, 2023, The results of the questionnaire on HR activities in the Institute have been published.
April 4, 2023, Our colleague, Václav Brázda, published a paper on the shark longevity.
March 31, 2023, EMBO course on writing research articles.
March 30, 2023, Photovoltaic power plant of the Institute represents an important sources of energy.
March 30, 2023, PR and HR activites of the Institute of Biophysics.
March 28, 2023, Thermo Fisher Scientific announces a grant 200 th. Czech Crowns for students or young scientific workers. The deadline is May 31, 2023.
March 28, 2023, Announcement of the 2-year stay for yougn scientists by the Thermo Fisher Scientific CZ and Czech Microscopic Society.
March 17, 2023, Our colleague, Vojta Hudzieczek, commented the law on gene editing.
March 16, 2023, How to clone a human? Biology and etical issues. Invivation to Prague, Hybernská Campus.
March 25, 2023, Night of Scientists - about secrets of science.
March 20, 2023, Invitation to the lecture on the "Origin of life" in Brno planetarim.
March 7, 2023, Congratulation to all women to their women's Day.
March 5, 2023, Institute announces positions of PR specialist and project manager.
February 28, 2023, Application laboratory of the Department of plant evolutionary genetics started a new project on the evaluation of the quality of land fertility.
February 24, 2023, Lecture of our colleague, Eduard Kenovský, on Origin of Life.
February 1, 2023, Our employee, Zuzana Machálková became an expert of the Ministry of the Environment.
January 31, 2023, Visualization of the bond of RNA to proteins by our Department of structural dynamics.
January 27, 2023, We are saddened to announce that our colleague, dr. Karel Nejedlý he has passed away.
January 27, 2023, Interesting work of dr. Lenka Stixová on DNA repair in tumour cells.
January 25, 2023, Dr. Jiří Široký became "Emeritus scientists" of the Czech Academy of Sciences
January 17, 2023, Graphical summary of the most important events of year 2022
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets: This activity leads to the popularisation of research and particularly IBP research to the public eyes showing the most interesting results of research as well as achievements of the Institute and its position among other research organisations. The action is open to the society interested in science. Number of contributions from the beginning of the year: 104 . Measurable indicator: numbere of likes = 240. Action 11.20 had high priority for HRS4R.
Current Status: in progress

Sub-Action 11.21
Title: Open Day, photo see here.
Detailed information: Institute of Biophysics, CAS was involved in the "Week of Czech Academy of Sciences" organized by the Czech Academy of Sciences. Scientists of the Institute prezented lectures and showed laboratories and particularly devices (e.g. microscopes) to interested students. Lectures: R. Hobza - Genetically modified organisms, J. Kasparkova - New drugs for cancer treatment, M. Fojta - Electrochemistry and biological sciences.
Responsible scientists: Eda Kejnovský
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: November 8, 2023, beginning at 9 h
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Measurable indicator: % of researchers involved in PR activities (80% of all researchers). Action 11.11 had high priority for HRS4R.
Current Status: Completed

Sub-Action 11.22
Title: Martin Falk one of the co-authors of the new RADIOBIOLOGY TEXTBOOK
Detailed information:  We are pleased and proud to announce that Assoc. Prof. RNDr. Martin Falk, Ph.D. from the Institute of Biophysics of the CAS co-authored and published a new textbook entitled RADIOBIOLOGY TEXTBOOK. The new book has been produced under the auspices of the European Radiation Research Society (ERRS), with about 100 authors working on it. The book fills a long-existing gap for a review book and textbook in the field. It is the latest textbook (1st edition) providing not only the basic knowledge of radiobiology that every undergraduate student should know, but also a book summarizing in an overview manner the most important broader spectrum of expanding information on advances in a wide range of radiobiological and (radio)medical fields. The interpretation is accompanied by numerous illustrations and real research data, and the basic knowledge that the reader should acquire after reading the chapter is highlighted and summarized in the form of clear tables. The book has approximately 600 pages, was published by Springer and is available as a FREE electronic download. It can be purchased in print form there for 53.49 euros (hardcover) or cheaper (paperback).
Responsible scientists: Martin Falk
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: October 2, 2023
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets students of radiobiology as well as general awareness of public about the importance of science. Action 11.22 has high priority for HRS4R.
Current Status: Completed

Sub-Action 11.23
Title: The Department of Structure and Dynamics of Nucleonic Acids (Jiri Sponer, see here) publishes a paper in the Journal of Chemical Theory and Computation.
Detailed information:  In the latest paper, the department of prof. J. Sponer identified a subtle yet visible force-field artifact that had eluded force-field developers for the past decade. The artifact is connected with a steric clash between atoms involved in base-phoshate interactions. The authors proposed and tested simple correction which is improving the performance of the the state-of-the-art RNA force field.
Responsible scientists: Jiri Sponer
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: November 11, 2023
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Action 11.23 has high priority for HRS4R.
Current Status: Completed

Sub-Action 11.24
Title: A new paper from the Department of Biophysics of the Immune System (Lukas Kubala).
Detailed information:  New research focusing on the immune system suggests that the adenylyl cyclase (AC) signaling pathway may play a key role in regulating immune system function. The study focused on the effects of cyclic adenosine monophosphate (cAMP) on the differentiation and function of T helper (Th) cells, specifically on the development of Th1, Th2 and Th17 subsets.
Responsible scientists: Lukas Kubala
GAP Principles: (+/-) 9. Public engagement, (++) 22. Recognition of the profession
Timing: November 17, 2023
Responsible Unit: Steering Commitee, WG, director of the Institute
Indicator(s)/Targets:  This activity targets general awareness of public about the importance of science. Action 11.24 has high priority for HRS4R.
Current Status: Completed

Report for 2022-2023
Title: Report on increased PR activities in 2022-2023
Detailed information: In 2022, we have presented research results in media and our web pages (series on „How radioactivity damages our cells“ by M. Falk, information about the project „Structural gymnastics of nucleic acids“ by M. Fojta and "New achievements in the research of anti-cancer drugs" by V. Brabec). These activities were continued in 2023 (Variability of "Inverted Repeats in All Available Genomes of Bacteria" by V. Brázda, "Banning plant DNA editing is evolutionary suicide" by R. Hobza, "G-quadruplexses in the evolution of hepatitis B virus" by J.L. Mergny, new "Radiobiology textbook" by Martin Falk, "Publication in the Journal of Chemical Theory and Computation" by Jiri Sponer and "A new paper from the Department of Biophysics of the Immune System" by Lukas Kubala). Regular information has been presented at Facebook (at least 75 contributions in 2022 and 99 contributions up to October 2023), Twitter or Youtube (series of lectures covering genetics and evolution 30 lectures in 2022 and 28 lectures in 2023). Within PR activities also organized the IBP Open Days, Spring Concert, Nights of Scientists. We have taken part in the Science Fairs in both years (see 11.5 and 11.15). We also participated in a large international actions "Mendel Festival in Brno" (see 11.6 and 11.19). We updated some parts of the IBP website (further improvements are needed).
Timing: report for 2022-2023.
Responsible Unit:  Steering Commitee, Working Group, PR manager: Eduard Kejnovský
Responsible Sub-Group: Eva Bártová, Iva Falková, Daniel Renčiuk, Pavel Vacek
Indicator(s)/Targets:  The PR manager together with other scientists provided activities related to PR („public relations“). PR activities consisted of contributions on the IBP web page, social media, including Facebook, and Twitter, participation at Open Days, Nights of Scientists, Science Fairs, Mendel Festivals or organizing Spring Concert and have lead to the promotion of IBP research and its reputation in the public eyes. PR activities were open for all R1-R4 categories, including students of all degrees, and secondary school students. The percentage of categories involved in this activities corresponded  approximately to the plan (40/30/20/10%). We have addressed the principles: 9, 22 and this activity has been directed to students of all categories and the public. Measurable indicator: % of employees actively participating in PR activities: 10%-90% from all employees. Action 11. has high priority for HRS4R, average priority for institutional strategy.
Current Status: Completed for 2022-2023, we will continue this activity with some improvements.

Action 12. (text from the Action Plan)
Title: An Improvement of job descriptions, advertisements, and strengthening of grant applications, and application to the Czech Academy of Sciences for postdoctoral support (PPLZ).
GAP Principles: 2, 4, 6, 9, 12, 13, 25, 26
Timing: Improvement of job descriptions for individual positions and implementation of a structured employee evaluation involving more transparent procedures (2. quarter of  2023). All employees, departments and groups must be well visible to the public eye as well as the scientific community. It will help us to improve the quality of research and working conditions. Positions will be advertised on the EURAXESS portal and the IBP web page (starting from the beginning of 2022). A piece of information on how to prolong an employment contract via the Institutional support of funding will be provided in the individual advertisement (2. quarter of  2023). 
Responsible Unit: Steering Commitee, WG, responsible scientist: Eda Kejnovsky
Indicator(s)/Targets: The numbers of advertisements on ERURAXESS portal are the measureable indicators. We will address all categories R1-R4, but a number of calls depend on the grant efficiency and the level of Institutional funding from the Czech Academy of Sciences. From this view, WG will encourage scientists to apply to local and EU grant agencies and postdocs for PPLZ support. Annually, we plan to apply for 10-15 standard projects and 1-3 junior projects, and 2-4 PPLZ supports. Action 12. has high priority for both institutional strategy and HRS4R.
Current Status: In progress
Remarkts:

Sub-Action 12.1
Title: Support of human resources by the Czech Academy of Sciences (Hana Švachová, Alena Kovaříková)
Timing: January 1, 2022
Responsible unit: Steering Commitee and Working Group
Indicator(s)/Targets: WG encouraged postdocs to apply for the support of human resources by the CAS. The following applications have been accepted: Hana Švachova "Regulation of DNA replication origins during cardiogenesis" and Alena Kovaříková "Epigenetic modifications of RNA molecules and their role in the repair of damaged DNA. The number of applications was optimal. We were 100% successful. Action 12.1. had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 12.2
Title: Strengthening of grant applications
Timing: 6 April, 2022
Responsible unit: Steering Commitee and Working Group
Indicator(s)/Targets: Working Group encouraged scientists to apply to local grant agency (GACR) and as a consequence the Institute have sent 26 applications (grant applications 2022). As compared to previous years, the number of applications approached 100%. The applications will be evaluated and some of them will be granted in the beginning of 2023. Action 12.2. has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 12.3
Title: Otto Wichterle prize awarded to Mgr. Petr Fajkus, PhD.
Detailed information: The award for young researchers is named after Professor Otto Wichterle in memory of the outstanding world-class Czech chemist who became president of the Czechoslovak Academy of Sciences after November 1989. It has been awarded since 2002 and is associated with a financial reward. The Academy of Sciences of the Czech Republic awards the Otto Wichterle Prize to selected, exceptionally high quality and promising researchers of the Academy of Sciences of the Czech Republic who contribute excellent results to the development of scientific knowledge, hold scientific degrees or degrees (CSc., Dr., Ph.D., DrSc., DSc. ) and reach a maximum age of 35 in the calendar year of the submission of the proposal. Proposals for the award of the premium are submitted by the directors of the institutes of the ASCR after consultation with the councils of the institutes. The most significant success of Petr Fajkus's work so far is the characterization of RNA subunits of plant telomerases.
Timing: June 20, 2022
Responsible unit: Steering Commitee and Working Group
Indicator(s)/Targets: The institute suggested 2 candidates for the prize of Otto Wichterle. Committee of the CAS selected one of them - Mgr. Petr Fajkus, PhD. Owing to the fact that the Academy awarded only 25 prizes (for 50 Institutes), the result is favorable for our Institute. Action 12.3. has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 12.4
Title: Support of human resources by the Czech Academy of Sciences (Viktor Tokan)
Timing: July 1, 2022
Responsible unit: Steering Commitee and Working Group
Indicator(s)/Targets: WG encouraged postdocs to apply for the support of human resources by the CAS. The following applications have been accepted: Viktor Tokan "Domestication of transposons at centromeres and telomeres: characterization and utilization". The number of applications (2) was optimal. One applicant has been supported. We were 50% successful. Action 12.4 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Sub-Action 12.5
Title: Support of human resources by the Czech Academy of Sciences 
Timing: September 21, 2022
Responsible unit: Steering Commitee and Working Group
Indicator(s)/Targets: WG encouraged postdocs to apply for the support of human resources by the CAS. The following applications have been suggested by the Council of the Institute: Monika Hermanová, Eva Vojtková. The number of applications (2) was optimal. Action 12.5 had high priority for both institutional strategy and HRS4R.
Current Status: Completed

Report for 2022
Title: Report on improvements of job descriptions, advertisements, and strengthening of grant applications, and application to the Czech Academy of Sciences for postdoctoral support (PPLZ) in 2022
Detailed information: Job descriptions have been improved, paricularly, we have established relation between EU R1-R4 positions and V1-V6 postions of the Czech Academy of Sciences (see here). Positions are advertised on the EURAXESS portal and the IBP web page (the quality of advertisements increases). We have applied to the Czech Grant Agency (GACR) (26 applications) as well as to the Czech Academy of Sciences (Support of Human Resources – 3 successful applications, Otto Wichterle prize – 1 successful application).  
Timing: report for 2022.
Responsible Unit:  Steering Commitee, WG
Indicator(s)/Targets:  Annually, we planed to apply for 10-15 standard projects and 1-3 junior projects, and 2-4 PPLZ supports, which was fullfilled. Measurable indicator: the number of advertisements on EURAXESS/total number of adveertisements – 100%; the number of successful applications to the Czech Academy of Sciences – 75%. The number of successful grant applications will be known in January 2023. Action 12.2. has high priority for both institutional strategy and HRS4R.
Current Status: Completed for 2022

Sub-Action 12.6
Title: Support of young researchers by Internal Support Research Program
Timing: January 20, 2023
Responsible unit: Council of the Institute, Steering Commitee and Working Group, Director of the Institute
Indicator(s)/Targets: Research in the Institute can be supported in the case of 3 types of projects: junior, pilot and bridging projects. Director decided to provide such support to 4 scientists: pilot project of V. Hudzieczek: Genome-wide analysis of transcription factor binding sites to identify regulatory networks controlled by sex chromosomes, pilot project of J. Lunerová: Epigenetic regulation of bivalent and univalent chromosomes in dogroses, junior project of P. Veverka: Clarification of the function of Codanin1 protein in regulation of deposition of histones by means of interaction with ASF1 and CDIN1, and pilot project of  V. Tichý: The role of non-coding RNA in the initiation of UV-induced DNA damage response.  Action 12.6 had high priority for both institutional strategy and HRS4R.
Current Status: In Progress

Sub-Action 12.7
Title: Strengthening of grant applications
Timing: April 3, 2023
Responsible unit: Steering Commitee and Working Group
Indicator(s)/Targets: Working Group encouraged scientists to apply to local grant agency (GACR) and as a consequence the Institute have sent in 2023 in total 22 applications (grant applications 2023). The number of applications was about 80% of maximum from previous years. The applications will be evaluated and some of them will be granted in the beginning of 2024. Action 12.7. has high priority for both institutional strategy and HRS4R.
Current Status: In Progress

Sub-Action 12.8
Title: Strengthening of grant applications (results of evaluation)
Detailed information: As a result of evaluation we have 5 projects granted, 3 project will be coordinated in the Institute, in 2 applications we will participate as partners (see our web page).
Timing: December 4, 2023
Responsible unit: Steering Commitee and Working Group
Indicator(s)/Targets: The Institute have sent in 2023 in total 22 applications (see 12.7). The number of granted applications is 3/22=14% This rate is similar to the general probability of success in national scale. Action 12.8. has high priority for both institutional strategy and HRS4R.
Current Status: Completed

Report for 2022-2023
Title: Report on improvements of job descriptions, advertisements, and strengthening of grant applications, and application to the Czech Academy of Sciences for postdoctoral support (PPLZ) in 2022 and 2023
Detailed information: Job descriptions have been improved, particularly, we have established relation between EU R1-R4 positions and V1-V6 postions of the Czech Academy of Sciences (see here). Positions are advertised on the EURAXESS portal and the IBP web page (the quality of advertisements approaches standards required by OTM-R, see the Action 2). We have applied to the Czech Grant Agency (GACR) (26 applications in 2022 and 22 applications in 2023) as well as to the Czech Academy of Sciences (Support of Human Resources, PPLZ – 3 successful applications in 2022, Otto Wichterle prize – 1 successful application in 2022; we were not successful in PPLZ and Otto Wichterle prize in 2023, however, the next application for PPLZ will be possible to the end of this year).  In addition, we have granted 4 scientists from the Internal Support of Research Program (see 12.6).
Timing: report for 2022-2023.
Responsible Unit:  Steering Commitee, WG
Responsible Sub-Group: Eva Bártová, Klára Bednářová, Daniel Renčiuk, Miroslav Krepl
Indicator(s)/Targets:  Annually, we planed to apply for 20-25 standard projects and 1-3 junior projects to the Czech Grant Agecy, and 2-4 PPLZ supports from the CAS, which was fullfilled. Measurable indicator: the number of advertisements on EURAXESS/total number of adveertisements – 100%; the number of successful applications to GACR (2022): 30%, the number of successful applications to the Czech Academy of Sciences – 40%. The number of successful grant applications for 2023 will be known in January 2023. Action 12 has high priority for both institutional strategy and HRS4R.
Current Status: Completed for 2022-2023, we will continue this activity in the next period of HRAW.

Action 13. (text from the Action Plan)
Title: Evaluation of departments and students by the International Advisory Board (ISAB) and the Czech Academy of Sciences.
GAP Principles: 24, 34, 36, 37, 40
Timing: ISAB will solve the most general problems of the Institute such as focusing on research in the most promising areas and establishment of new departments or reduction of less successful ones (meetings are biannual, the next meeting is planned in 2023). We are keen to build new laboratories at the Institute. During sessions of the Attestation Commission, all department leaders will be motivated to improve the quality of research and working conditions at their laboratories. Students will be evaluated annually (at the end of the year). Working group will encourage department leaders to find new motivation tolls for the work of excellent students. We have to find a way how to recruit the best students of local universities, and these students must fruitfully interact with their supervisors.
Responsible Unit: Steering Committee, Director and ISAB members, WG
Indicator(s)/Targets: Every 2nd year, ISAB will evaluate individual departments, the Director, the scientific incubator and the progress of Internal support of science. Annually, the Attestation Commission will evaluate categorization R1-R4, and every 5th year the Czech Academy of Sciences evaluation departments and the whole institute.
Minutes from the meetings will be available online on the HRS4R IBP web page. All categories R1-R4 will be engaged in this activity. Measurable indicator: number of departments (students) evaluated positively/total numbers. Action 13. has high priority for institutional strategy, average priority for HRS4R.
Current Status: In progress
Remarks:

Sub-Action 13.1
Title: ISAB meeting (see Program)
Meeting program:   Introductory prezentation by the director of the Institute, Eva Bártová (see picture). Main points of the program: 1) The ISAB statement for OP-JAC project – how to make the project attractive, and we need a short recommendation. 2) Selection of 2 of the best young scientists (students) awarded by the ISAB - the ISAB Award, 3) ISAB opinion if we should publish in MDPI journals, 4) A motivation tool for department leaders how to recruit young scientists with the potential to apply for, e.g., Junior Star and Lumina Queruntur projects (200 000 Euro/year for 4-5 years – to build new teams), 5) Recommendation of prof. Mergny for a new contract that will also be discussed by the Institutional Council – how to continue in cooperation. In addition, we presented to ISAB our recruitment procedure including new "Internal regulation on recruitment and selection".
GAP Principles: 24, 34, 36, 37, 40
Timing: October 6, 2022
Responsible unit: Steering Committee, Director and ISAB members, WG
Indicator(s)/Targets: This meeting program involved mainly prezentations of young scientists (students or postdocs): Vojtěch Novohradský, Soňa Legartová, Petr Fajkus, Monika Hermanová, Radka Vozárová, Ondřej Vacek, Miroslav Krepl, Viktor Tokan, Jan Víteček and Tereza Pavlícová.  All young scientists prezented their research results and directions. Measurable indicator: 100%. Action 4.3 had high priority for both institutional strategy and for HRS4R. ISAB will decide about the quality of prezentations and speakers. ISAB approved our recruitment guidelines and the whole process.
Number of participants form the Institute: 45
Current status: Completed

Sub-Action 13.2
Title: Evaluation of students by the International Advisory Board (ISAB)
Detailed information:   During the ISAB meeting research results of postdocs and PhD students have been presented. Subsequently, ISAB evaluated these presentation and selected the best postdocs and student. In the category of students the award of the best presentation (and the best research results) has obtained Radky Vozárová (see here).
GAP Principles: 24, 34, 36, 37, 40
Timing: October 6, 2022
Responsible unit: Steering Committee, Director and ISAB members, WG
Indicator(s)/Targets: This meeting program involved mainly presentations of young scientists (students or postdocs): see 13.1.  All young scientists prezented their research results and directions. Measurable indicator: 100%. Action 4.3 had high priority for both institutional strategy and for HRS4R. ISAB will decide about the quality of presentations and speakers.
Number of participants form the Institute: 45
Current status: Completed

Report for 2022
Title: Report on the evaluation of departments and students by the International Advisory Board (ISAB) and the Czech Academy of Sciences in 2022
Detailed information: Hybrid meeting of ISAB was organized on October 6, 2022. The program involved introductory prezentation by the director of the Institute, Eva Bártová. Main points of the program were the following: 1) The ISAB statement for OP-JAC project. 2) Selection of 2 of the best young scientists (students) awarded by the ISAB, 3) ISAB opinion on MDPI journals, 4) Recruitment of young scientists to build new teams), 5) Recommendation of prof. Mergny for a new contract. In order to encourage excellent young scientists and students in their research, ISAB evaluated presentations and subsequently 2 young scientists and 1 student obtained a prize awarded by the director, Eva Bártová (see 5.1 and 13.2).
Timing: report for 2022.
Responsible Unit:  Steering Committee, Director and ISAB members, WG
Indicator(s)/Targets:  Evaluation of the depertments by ISAB is planned for the next year as well as the discussion on other important problems related to the functioning of the Institute. Measurable indicator: number of presentations of young scientists or students evaluated positively/total number of presentations – near to 80%.  Action 12 has high priority for both institutional strategy and HRS4R.
Current Status: Completed for 2022

Sub-Action 13.3
Title: National evaluation of our Institute in 2023 (results)
Detailed information: National evalution consists of of peer-review of a few papers (7 papers for our Institute), bibliometry of the total output for 5 years and comparison of the first quartile and decile of the best papers (according to the scale defined by AIS) with EU15, world and Czech Republic. Socio-economical impact, quality of management, international collaborations and proposed plans for the next period are also considered by the panel of stakeholders. National evalutation has been introduced for 5 years and in 2022/2023 achieved its final extent and quality.
Timing: Evaluation has been performed for years 2017-2020 and finished at the end of 2022/beginning 2023
GAP Principles: 4, 10, 11, 15, 23
Responsible Unit: Collegium of the Director, Director of the Institute
Indicator(s)/Targets: Measurable indicators: comparison to EU and world standards - in all main FORD fields of the Institute the production of outputs in the top decile and top quartile is higher or at the level of EU15 and substantially higher as compared with national levels. Based on these results, the final decision of the evaluation panel was that the Institute is among the best research organizations in the Czech Academy of Science (category A). Action 13.3 has high priority for institutional strategy average priority for HRS4R. 
Current Status: Completed
Remarks: The basic results and experience from the national evaluation have been presented at the Conference on the implementation of the national evaluation M17+ in Pardubice which was held on 15 June, 2023.

Report for 2022-2023
Title: Report on the evaluation of departments and students by the International Advisory Board (ISAB) and the Czech Academy of Sciences in 2022-2023
Detailed information: Hybrid meeting of ISAB was organized on October 6, 2022. The program involved introductory prezentation by the director of the Institute, Eva Bártová. Main points of the program were the following: 1) The ISAB statement for OP-JAC project. 2) Selection of 2 of the best young scientists (students) awarded by the ISAB, 3) ISAB opinion on MDPI journals, 4) Recruitment of young scientists to build new teams), 5) Recommendation of prof. Mergny for a new contract. In order to encourage excellent young scientists and students in their research, ISAB evaluated presentations and subsequently 2 young scientists and 1 student obtained a prize awarded by the director, Eva Bártová (see 5.1 and 13.2). In 2023, we had no ISAB meeting owing to more detailed national evaluation (see 13.3) and financial situation (reduction of financial support of research in 2024 by 10%), which do not allow substantial changes or investments in the subsequent year. We can rely on results of evaluation by the Czech Academy of Sciences in 2020 and more recently on the latest evaluation by M17+ methodology (national evaluation).
Timing: report for 2022-2023.
Responsible Unit:  Steering Committee, Director and ISAB members, WG
Responsible Sub-Group: Eva Bártová, Stanislav Kozubek, Bohuslav Janoušek, Olga Nováková
Indicator(s)/Targets:  Evaluation of the depertments by ISAB is planned for the year 2024 as well as the discussion on other important problems related to the functioning of the Institute. Measurable indicator: number of presentations of young scientists or students evaluated positively/total number of presentations – near to 80%.  Action 12 has high priority for both institutional strategy and HRS4R.
Current Status: Completed for 2022-2023, the action will be continued in the next period and will be focused more to the ARRA document adopted by EU.

Action 14. (text from the Action Plan)
Title: Summer schools
GAP Principles: 9, 33
Timing: We are going to organize Summer school (2.-3. quareter each year) in a frame of IBP activity and the activity of the Society for the Czech biophysics, This school will be intended for kids of employees who will participate as mentors and will familiarize their kids with basic principles of laboratory work, biophysics, biology and chemistry. 
Responsible Unit: WG, management of the institute
Indicator(s)/Targets: Approximately 15-20 mentors from the IBP will organize the Summer schools each year. The percentage of R1-R4 categories involved in this activity is the following: 25/40/25/10. Measurable indicator: the number of children participating. Action 14. has high priority for HRS4R.
Current Status: In progress
Remarks:

Sub-Action 14.1
Title: Summer school of biophysical sciences for children (6-10 years old) (invitation see here, photos see here: 1, 2, 3, 4, 5)
Detailed information: Batch I. Day 1 (Monday), Responsible person: A. Daňhel, Listening stories, coloring books, books, magazines, welcome (8:15-8:30) (J. Poláková, P. Novotná, dating games), dancing (L. Stixová), crystal making (clubhouse) (Daňhel A., Poláková J), snack, flame tests (Daňhel A., D. Kovaříková), leisure in the garden (singing and musical instruments) (M. Fojta), principle and examples of 3D printing (birds, DNA bases) and making a DNA model from paper/skewers/string of self-hardening compound and cutters (A. Daňhel, J. Poláková, J. Kovařík), football (field). Day 2 (Tuesday) Responsible person J. Kašpárková. Listening fairy tales, coloring books, books, magazines (J. Poláková), dancing (L. Stixová), t-shirt production (J. Kašpárková, L. Stixová), snack, making a fizzy bath bomb (J. Poláková, Grodecká), leisure in the garden (singing and musical instruments) (Čegan, Novotná, Grodecká), The World Around Us (S. Kozubek), fumes and foam (A. Daňhel), football (field). Day 3 (Wednesday), Responsible person: E. Bártová, Listening stories, coloring books, books, magazines (J. Poláková), dancing (L. Stixová), collection of samples for microscopy (garden), funnels, examination under a microscope (V. Hudziecek, L. Stixová), snack (J. Kovařík), examination of objects under a microscope and a demonstration of a confocal microscope (E. Bártová), free time in the garden, singing, musical instruments (Čegan, Novotná, Grodecká), collection of plants for the herbarium (A.  Daňhle, D. Kovaříková), snack, tossed around/petanque (E. Bártová, J. Poláková). Day 4 (Thursday), Responsible person: M. Hermanová, Listening stories, coloring books, books, magazines (J. Poláková), dancing (L. Stixová), flowers and fruits as pH indicators (clubhouse), (M. Hermanová, V. Skočková, H. Kašparová), snack, experiments with vacuum, color mixing (P. Fajkus, M. Hermanová), free time in the garden, singing, musical instruments (Čegan, Novotná, Grodecká), pipetting and volume measurement (clubroom), box filling competition (M. Hermanová), snack, athletics, long jump, long throw, target throw, boat race, Day 5 (Friday) Responsible person: V. Hudzieczek, Listening stories, coloring books, books, magazines (J. Poláková), dancing (L. Stixová), a day with the bees (A. Hyršlová, A. Vaculová, P. Hyršl), snack, a day with the bees (A. Hyršlová, A. Vaculová, P. Hyršl), free time in the garden, singing, musical instruments (Čegan, Novotná, Grodecká), slime production (H. Kašparová, M. Hermanová), snack, roasting. Meeting with parents was organized where working conditions and possible improvements had been discussed.  
Timing: 18.7.-22.7.2022
Responsible Unit: WG, management of the institute, responsible scientist: Aleš Daňhel (danhel@ibp.cz)
Indicator(s)/Targets: Approximately 15-20 mentors from the IBP will organize the Summer school. Measurable indicator: the number of children participating: 10. Action 14.1 had high priority for HRS4R. 
Current Status: Completed

Sub-Action 14.2
Title: Summer school of biophysical sciences for children (6-10 years old) (invitation see here, photos will be provided)
Detailed information: Batch II. Day 1 (Monday), Responsible person: A. Daňhel, Listening stories, coloring books, books, magazines, welcome (8:15-8:30), crystal making (clubhouse) (Daňhel A., Suchánková T.), snack, precipitation reaction (A. Daňhel, T. Suchánková), lunch, leisure in the garden (singing and musical instruments) (Čegan, Novotná, Grodecká), principle and examples of 3D printing (birds, DNA cutters, DNA model production from paper/glue/string, self-hardening material/cutters (A. Daňhel, J. Poláková), snack, football (field) (A. Daňhel); Day 2 (Tuesday) Responsible person K. Řehůřková. Listening fairy tales, coloring books, books, magazines, nitrogen, snack, isolation of DNA, lunch, leisure in the garden (singing and musical instruments) (Čegan, Novotná, Grodecká), production of medals from clay, athletics (long jump, long throw, target throw, sprint); Day 3 (Wednesday), Responsible person: J. Poláková, Listening stories, coloring books, books, magazines, a day with bees - R. Hobza and R. Čegan, snack, a day with bees - R. Hobza and R. Čegan, luch, leisure in the garden (singing and musical instruments) (Čegan, Novotná, Grodecká), snack, tossing, petanque (E. Bártová); Day 4 (Thursday), Responsible person: L. Grodecká, dancing(L. Stixová), T-shirt production (L. Grodecká), making a fizzy bath bomb (J. Poláková, L. Grodecká), lunch, leisure in the garden (singing and musical instruments) (Čegan, Novotná, Grodecká), snack, football (field); Day 5 (Friday) Responsible person: T. Suchánková, Listening stories, coloring books, books, magazines (J. Poláková), lunch, leisure in the garden (singing and musical instruments) (Čegan, Novotná, Grodecká), fighting game/tracking in the garden (T. Suchánková), roasting (all). Meeting with parents was organized where working conditions and possible improvements had been discussed (see "Meeting for parents in science").
Timing: 8.8.-12.8.2022
Responsible Unit: WG, management of the institute, responsible scientist: Aleš Daňhel (danhel@ibp.cz)
Indicator(s)/Targets: Approximately 15-20 mentors from the IBP will organize the Summer school. Measurable indicator: the number of children participating: 9. Action 14.2 has high priority for HRS4R. 
Current Status: Completed

Report for 2022
Title: Report on „Summer Schools“ in 2022
Detailed information: Summer schools have been organized on July 18-22, 2022 and August 8-12, 2022 in the frame of IBP activity and the activity of the Czech Biophysical Association. The schools were devoted to kids of employees who participated as mentors. The kids were familiarized with laboratory work and science in very popular way (for detailed description see 14.1 and 14.2). Meeting with parents was organized where working conditions and possible improvements were discussed.
Timing: report for 2022.
Responsible Unit:  Steering Committee, Director and ISAB members, WG, responsible scientist: Aleš Daňhel.
Indicator(s)/Targets: Approximately 15-20 mentors from IBP participated in the organization of the Summer schools. The percentage of R1-R4 categories involved in this activity was corresponded approximately to the earlier plan: 25/40/25/10%. Measurable indicator: the number of children participating 9-10.  Action 14 had high priority for HRS4R.
Current Status: Completed for 2022

Sub-Action 14.3
Title: Summer school of biophysical sciences for children (6-10 years old) (invitation see here, photos see here:1, 2, 3, 4, 5, 6, 7, 8, 9, 10)
Detailed information: Children of employees of the Biophysical Institute participated in the summer school of biophysics, which the Institute organized together with the Czech Biophysical Association in the week from 10.7. to 14.7.2023. During the week, the children became familiar with microscopic techniques, DNA isolation, make their own herbarium, soap, and are shown some simple chemical experiments. The last day, they played with flowers and fruits as pH indicators and at the end there had to be good in old-fashioned roasting.
Timing: 10.7.-14.7.2023
Responsible Unit: WG, management of the institute, responsible scientist: Aleš Daňhel (danhel@ibp.cz)
Indicator(s)/Targets: Approximately 15-20 mentors from the IBP will organize the Summer school. Measurable indicator: the number of children participating: 14. Action 14.3 had high priority for HRS4R. 
Current Status: Completed

Sub-Action 14.4
Title: Summer school of biophysical sciences for children (6-10 years old) (photos see here:1, 2, 3, 4, 5)
Detailed information: Children of employees of the Biophysical Institute participated in the summer school of biophysics, which the Institute organized together with the Czech Biophysical Association in the week from 14.8. to 18.8.2023. During the week, the children became familiar with a number of simple techniques (pipetting, bioinformatics as a game, entomological window, creation of a soap, senses - smell, taste, touch, plants in the herbarium, etc). The last day, they played football, petanque and competed in athletics.
Timing: 14.8.-18.8.2023
Responsible Unit: WG, management of the institute, responsible scientist: Aleš Daňhel (danhel@ibp.cz)
Indicator(s)/Targets: Approximately 15-20 mentors from the IBP will organize the Summer school. Measurable indicator: the number of children participating: 15. Action 14.4 had high priority for HRS4R. 
Current Status: Completed

Report for 2022-2023
Title: Report on „Summer Schools“ in 2022-2023
Detailed information: Summer schools have been organized on July 18-22, 2022 and August 8-12, 2022 in the frame of IBP activity and the activity of the Czech Biophysical Association. Also in 2023 similar school has been organized on July 10-14, 2023 and in August, 2023. The schools were devoted to kids of employees who participated as mentors. The kids were familiarized with laboratory work and science in very popular way (for detailed description see 14.1, 14.2, and 14.3). Meetings with parents were organized where working conditions and possible improvements were discussed.
Timing: report for 2022-2023.
Responsible Unit:  Steering Committee, Director and ISAB members, WG, responsible scientist: Aleš Daňhel.
Responsible Sub-Group: Eva Bártová, Aleš Daňhel, Kateřina Svobodová, Radek Fedr
Indicator(s)/Targets: Approximately 15-20 mentors from IBP participated in the organization of the Summer schools. The percentage of R1-R4 categories involved in this activity was corresponded approximately to the earlier plan: 25/40/25/10%. Measurable indicator: the number of children participating 9-10 in 2022 and 12 in 2023.  Action 14 has high priority for HRS4R.
Current Status: Completed for 2022-2023, we will continue this acitivity in the next period of HRAW.