Contacts

Group head: 

Roman Pleskot

Centre: 

Lysolaje

Address: 

Rozvojová 263, 165 02 Praha 6 - Lysolaje, Česká republika

Email: 

pleskotueb [dot] cas [dot] cz

Phone: 

+420 225 106 407

The laboratory aims to understand how the wiring of different biomolecules drives fundamental processes of the plant cell, such as cytokinesis, cell-wall material secretion or nutrient uptake. We employ a multidisciplinary strategy combining experimental and computational approaches to achieve this goal. We utilise methods of molecular biology, biochemistry and state-of-the-art microscopy. By combining the experimental techniques with the computational ones (structural bioinformatics, molecular dynamics) in an integrative fashion, we can obtain unprecedented details of a given process, leading to novel biological implications.

Keywords

Integrative Structural Biology, Structural Bioinformatics, Molecular Dynamics, Biochemistry, Microscopy, Cell Division, Callose Synthesis, Endocytosis, TPLATE complex, protein-membrane interfaces.