Optical Biosensors

Focus

The team is engaged in the research of photonic and plasmonic (nano) structures and functional biomolecular files, the development of optical measuring methods and systems, the study of biomolecular interactions and detection of chemical and biological agents in areas such as medical diagnostics, food quality control or environmental monitoring.

Research projects

• Multifunctional nanostructures for plasmonic sensing of biomolecules related to oncohematological diseases
• Novel biophotonic tools for investigation of cellular processes
• Advanced plasmonic biosensors: towards the next-generation biomolecular interaction analysis

Complete overview of research projects

Publications

1. A. Libánská, T. Špringer, L. Peštová, K. Kotalík, R. Konefał, A. Šimonová, T. Křížek, J. Homola, E. Randárová, T. Etrych: Using surface plasmon resonance, capillary electrophoresis and diffusion-ordered NMR spectroscopy to study drug release kinetics, Communications Chemistry 6, Article number: 180 (2023). doi
2. L. Chrastinová, O. Pastva, M. Bocková, H. Kovářová, E. Ceznerová, R. Kotlín, P. Pecherková, J. Štikarová, A. Hlaváčková, M. Havlíček, J. Válka, J. Homola & J. Suttnar: Linking aberrant glycosylation of plasma glycoproteins with progression of myelodysplastic syndromes: a study based on plasmonic biosensor and lectin array, Scientific Reports volume 13, Article number: 12816 (2023).
3. T. Wiste, O. Maliuk, V. Tikhonchuk, T. Lastovicka, J. Homola, K. Chadt, S. Weber: Additive manufactured foam targets for experiments on high-power laser–matter interaction, Journal of Applied Physics, 133, 043101 (2023).
4. J. Slabý, J. Homola, Performance of label-free optical biosensors: What is figure of merit (not) telling us?, Biosensors and Bioelectronics, Volume 212, 114426 (2022). 
5. Y. Wang, A. Kálosi, Y. Halahovets, I. Romanenko, J. Slabý, J. Homola, J. Svoboda, A. de los Santos Pereira, O. Pop-Georgievski, Grafting density and antifouling properties of poly[N-(2-hydroxypropyl) methacrylamide] brushes prepared by “grafting to” and “grafting from”, Polymer Chemistry 13, 3815-3826 (2022).

Complete overview of publications