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Centrum pro inovace v oboru nanomateriálů a nanotechnologií

Department of Biophysical Chemistry

 Oddělení teoretické chemie    Oddělení fotochemie, spektroskopie a iontové chemie    Oddělení biofyzikální chemie    Oddělení struktury a dynamiky v katalýze    Oddělení syntézy a katalýzy    Oddělení elektrochemických materiálů    Oddělení elektrokatalýzy    Oddělení molekulární elektrochemie   

About the Department

Management

Head of the Department



Deputy Head


Research interests

Development of new fluorescence methods and their application in the research of structure, functionality and dynamics of biomembranes; single molecule spectroscopy in biological systems, dynamics characterization in model and biomembranes on the picosecond to millisecond time scale; characterisation of DNA condensation processes relevant to gene therapy; advanced in vivo fluorescence microscopy.

Elucidation of the function of biologically active molecules based on their electrochemical reactivity. The interim aims will be the elucidation of (i) creation and stability of monolayers on polarized interfaces and (ii) charge transfer reactions.

Biospectroscopy Group

presentation video (in Czech):download

Leader: Doc. HOF Martin, Dr. rer. nat. DSc.

Members:
Mgr. BENDA Aleš, Ph. D.
Mgr. HUMPOLIČKOVÁ Jana, Ph. D.
Mgr. JURKIEWICZ Piotr, Ph.D.
Dr. KRAL Tereza
Mgr. MISZTA Adam
Mgr. SÝKORA Jan, Ph. D.

Student(s):
Mgr. BARUCHA - KRASZEWSKA Justyna
Mgr. BERANOVÁ Lenka
Mgr. MACHÁŇ Radek
Mgr. ŠACHL Radek
Mgr. ŠTEFL Martin
Mgr. ZAŃ - KULAKOWSKA Anna


Other students:
Mgr. Alena Semerádtová (Ph. D. student, Faculty of Biomedical Engineering, Czech Technical University in Prague).


Laboratory is oriented towards:
  • Applications of the solvent relaxation technique in biomembrane and protein research;

  • development and applications of new variants of Fluorescence Correlation Spectroscopy (z-scan FCS, Lifetimes FCS);

  • tryptophan fluorescence in protein sciences;

  • characterisation of Supported Lipid Bilayers (SLB’s) by ellipsometry, Laser Scanning Microscopy (LSM), and FCS;.

  • function of antibacterial peptides; interaction with SLB’s;

  • DNA condensation and FCS;

  • advanced in vivo imaging.


Bioelectrochemistry Group

Leader: Prof. Ing. MAREČEK Vladimír, DrSc.

Members:
HEYROVSKÝ Michael, Ph. D.
RNDr. HOLUB Karel, CSc.
RNDr. JÄNCHENOVÁ Hana
Prof. RNDr. KALVODA Robert, DrSc.
Dr. Ing. NAVRÁTIL Tomáš
RNDr. ŠESTÁKOVÁ Ivana, CSc.
YOSYPCHUK Bogdan, Ph. D.

Student(s):
Mgr. ŠUSTROVÁ Barbora

Students:
Mgr. Aleš Daňhel, Mgr. Ivan Jiránek (Ph. D. students, Faculty of Science, Charles University, Prague);
Kamila Szabová (undergraduate, Institute of Chemical Technology, Prague);
Martina Parisová (bachelor study, Faculty of Science, Charles University, Prague);
Pavel Jakubec (secondary school students).

Laboratory is oriented towards:
  • preparation and characterization of phospholipid bilayers at stabilized phase boundaries enabling studies of transfer of charged and uncharged species between the two phases;

  • studies of transfer of charged and uncharged species between the two phases;

  • transport of compounds across the model membrane using cell permeable peptides;

  • studies on electrochemical properties of biologically important species;

  • development of new types of electrochemical sensors, devices and methods for following DNA, proteins and other biologically active substances;

  • novel techniques of DNA damage detection;

  • research on function and structure of metallothioneins and phytochelatins (bioligands);

  • biophysical and biochemical problems accompanying utilization of electrochemical techniques;

  • state of solutions and its effect on electrode processes;

  • bioavailable forms of trace elements present in soil solution and their availability to plants.


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