Joint Laboratory of IEB AS CR, v.v.i. and CRI, v.v.i.

GRANTS AND PROJECTS

International Projects

• Quantitative and qualitative determination of secondary metabolites in Coffea arabica. Universita Hamburk, (1991 - 1994) T. Vanìk
• Fate of the pesticides in the soil and environment. Project EC COST, COST 66.20, (1993-1998) T. Vanìk
• Biotransformation of xenobiotic compounds by plant cells. Swiss National Science Foundation, No. 7TPR J038652, (1994 - 1995) T. Vanìk
• The development of integrated system for large-scale propagation of elite plants using in vitro techniques. Project EC COST, COST 822.20, (1995 - 1999) T. Vanìk
• Regulation der Stressreaktionen durch Brassinosteroide bei Pflanzen. German Federal Ministry of Education and Research, Bilateral co-operation Czech-Germany No. TSR-043-97 (1997-99), Max-Planck-Institut f. Zuchtungsforschung, Koln - C. Koncz and IOCB AS CR - T. Macek
• Study of secondary metabolites with anticancer activity from medicinal plants of chinese origin. Grant of bilateral czech - chinese cooperation, No. 34-04, (1998-2000) T. Vanìk
• Synthesis of brassinosteroids and carrier-bound BS-analogues for isolation of plant receptors of brassinosteroid hormones. GA AV, No. A4055803, (1998-2001) T. Macek
• COST - Plant biotechnology for the removal of organic polutants and toxic metals from wastewaters and contaminated soils. No. COST 837.10 (1998-2003) T. Vanìk
• Quality enhancement of plant production through tissue culture. Project EC COST, No. COST 843.10, (2000-2004) T. Vanìk
• Theoretical and practical aspects of TNT phytoremediation. Bilateral cooperation Czech-Germany No. CZE 01/024, (2001-2004), Wasag Decon GmbH, Sythen - H. Thomas and IOCB AS CR - T. Vanìk
• Scale up and automation of in vitro-systems for rapid plant propagation and production of secondary metabolites. Bilateral cooperation Czech-Austria No. ME671 (2003-2004), Centre of Pharmacy, University of Vienna - C. Wawrosch and IOCB AS CR - T. Vanìk
• PhytoDec, EU project EVK1-CT-1999-00024, (2002-2004) T. Vanek
• Scale up and automation of in vitro-systems for rapid plant propagation and production of secondary metabolites, Kontakt ME671, (2003 - 2004), T. Vanìk
• Screen and identification of the bioactive Chinese pumpkin polysacharide, 37-15
  Chinese side: Professor Jidong Lou, College of Life Sciences, China Jiliang University
  Czech side: dr. Tomáš Vanìk, The Institute of Organic Chemistry and Biochemistry, ASCR, (2005-2007)
• Multidisciplinary study of the mechanism of phytoremediation of xenobiotics polluted soil and water, 37-30
  Chinese side: Professor Yongming Luo, Institute of Soil science, CAS
  Czech side: dr. Tomáš Vanìk, The Institute of Organic Chemistry and Biochemistry, ASCR, Praha, (2005-2007)
• Physiological and molecular basis of plant responses to pollution with nitroaromatic compounds, Èesko-Polská bilaterální spolupráce è. 40, 2006-2007, T. Vanìk
• COST 926: Impact of new technologies on the health benefits and safety of bioactive plant compounds, (2004 - 2008), T. Vanìk
• Cost 859: Phytotechnologies to promote sustainable land use management and improve food chain safety (2005 - 2009), T. Vanìk .
• COST 636: Xenobiotics in the urban water cycle, (2005 - 2009), T. Vanìk
• COST FA 0605: Study of plant response to heavy metal stress and production of stress protective compounds, (2009-2011), P. Soudek

National Projects

• Study of production of taxol and its analogues by plant tissue cultures, Grant Agency AS, No. 555114, (1993-1995) T. Vanìk
• Biotransformation of xenobiotics by plant tissue cultures, Grant Agency CR, No. 204/93/0836, (1993-1996) T. Vanìk
• Biotransformation of ergot alkaloids by plant peroxidases. Grant Agency AS, No. A455409, (1994-1996) T. Macek (co-investigator)
• Influence of exogennous carbohydrates on their endogenous levels and production of biologically active metabolites in plant cell cultures. Grant Agency of Charles University, No. 102 1994, (1994-1995) T. Vanìk (co-investigator)
• Production and biotransformation of biologically active compounds by plant cell cultures. Grant Agency CR, No. 203/94/0644, (1994-1996) T. Vanìk
• Studies on taxol preparation by plant tissue cultures. Lachema Comp. - Lachema 95/1744/51 (1995) T. Vanìk
• Research on Stevia as a source of natural non-saccharic sweetener. Grant Agency CR, No. 503/95/0249, (1995-1997) T. Vanìk (co-investigator)
• Biotransformation of natural compounds by plant enzymes. Grant Agency CR, 203/96/1267, (1996-1998) T. Macek (co-investigator)
• Studies of biodegradation of polychlorinated biphenyls by plant cells. Grant Agency CR, No. 203/96/0499, (1996-1998) T. Macek (co-investigator)
• Production of taxol and its analogs by in vitro cultivated plant cells of the taxus species. Grant Agency AS, No. A5055601, (1996-1998) T. Vanìk
• Studies on mechanism of regulation of cytokinine content and their activity in plant cells. Grant Agency CR, No. 204/96/1429, (1996-1998) T. Vanìk (co-investigator)
• Preservation and reproduction of gene sources of the main types of forest trees. Grant Agency CR, No. 522/96/K18, (1996-2001), T. Vanìk(co-investigator)
• Regulation of stress reactions in plants by brassinosteroids. Czech Ministry of Education, Project Kontakt ME-081, (1997-99) T. Macek
• Optimalization of technologies for growth, genetic material selection and screening of the content of active compounds in tonizating plants. Czech Min. of Agriculture - NAZV EP7227, CZU, (1997-2000) T. Vanìk (co-investigator)
• Preparation of Taxol and its analogues. Czech Min. of Industry and Trade, No. PZ CH/33, (1997-2001) T. Vanìk
• Synthesis of brassinosteroids and carrier-bound BS-analogues for isolation of plant receptors of brassinosteroid hormones. Grant Agency AS, No. A4055803, (1998-2001) T. Macek
• The study of the role of enzymes cytochrom P450 and peroxidases in the metabolism of xenobiotics by plants. Grant Agency CR, No. 203/99/1628, (1999-2001) T. Macek (co-investigator)
• Products of the metabolisation of polychlorinated biphenyls by plant cells. Grant Agency AS, No. B6127901, (1999-2001) T. Macek (co-investigator)
• Preparation of transgenic plant systems with increased ability to metabolise organic xenobiotics. Bilateral co-operation Czech Acad. Sci - Hungarian Acad. Sci., No. Cz/Hu-14 (Biol. Res. Center, Szeged - M. Szekeres). (1999-2001) T. Macek (co-investigator)
• Studies of phytoremediation of explosives by tissue cultures of higher plants. Grant Agency CR, No. 206/99/1252, (1999-2001) T. Vanìk
• Studies of the key enzyme in phytoremediation of explosives. Grant Agency CR, No. 206/99/P034, (1999-2001) A. Nepovím
• Plant tissue cultures as a model system for studies of phytoremediation of radionuclides released into the environment, Grant Agency AS, No. A6055902, (1999-2002) T. Vanìk
• Radiophytoremediation and radiophytomonitoring, Grant Agency AS, No. S S4055014, (2000-2004), T. Vanìk
• Strategies for the improvement of secondary metabolite production in plant cell culture of Panax species. Grant Agency CR, No. 521/02/P064, (2002-2004) L. Langhansová
• Study of enzymes participating in degradation of TNT. Grant Agency CR, No. 206/02/P065, (2002-2004) A. Nepovím
• Screening of antibacterial and anti/inflamatory activity of selected species of genus Nigella L. Grant Agency CR, No. 525/02/0257, (2002-2004) A. Nepovím (co-investigator)
• Preparation of taxol and its analogues. Grant Agency AS, No. IBS 4055301, (2003-2005) T. Vanìk
• Study of accumulation of toxic metals by plants from genus Allium and determination of possible mechanisms of uptake. Grant Agency CR, No. 522/06/P002, (2006-2008) P. Soudek
• Woody plants for soil decontamination, 526/04/0135, Dr. Malá, VULHM (2004-2006), T. Vanìk (co-investigator)
• Modern methods for explosive waste-waters cleaning, MPO, Tandem, Explosia, (2006-2008), T. Vanìk (co-investigator)
• Research centre: Functional genomics and proteomics for crop improvement (2006 - 2009), T. Vanìk (co-investigator)
• Projekt NPVII : The use of genomics and genetic engineering for identification and development of plant genotypes suitable for environment bioremediation, (2006 - 2011), T. Vanìk (co-investigator)
• Application of metabolomics on observation of induced production of plant secondary metabolites, Grant Agency AS CR, No. KJB400550705, (2007 - 2009), P. Maršík
• Biotechnological production and evaluation of biological activity of Vaccinium bracteatum, ME8070, (2008-2012), T. Vanìk
• Project NPVII 2B08058: Efective using of energetic plants for reclamation and sanitation of  devastation fields, (2008- 2011), T. Vanìk
• Project MZP SP/1b7/129/08: Green technology for air protection, (2008-2010), T. Vanìk
• Anti-inflammatory activity of plant quinones. Grant Agency CR, No. 525/09/P528 , (2009-2011) P. Landa