See full texts of the following patents:PREPARATION OF COPOLYMERS FOR PREVENTION AND HEALING OF INFLAMMATION AFFECTIONS
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AUTHOR(S): Labsky J., Vacik J., Hosek P. (CORPORATE SOURCE Ustav Makromolekularni Chemie Akademie Ved Ceske Republiky, Czech Rep.).
CHEMICAL ABSTRACTS: 131:32273
SOURCE PCT: Int. Appl. WO 9928359 A1 10 Jun 1999, 54 pp.
DESIGNATED STATES: W: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW, AM, AZ, BY, KG, KZ, MD, RU, TJ, TM; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG. (English). (World Intellectual Property Organization).
ABSTRACT: A preparation for prevention and healing of inflammation affections comprising in an amount of 0.1 to 99.9 % by weight derivatives of sterically hindered amines selected from the group consisting of: soluble polymers or copolymers prepared by radical polymerization in the presence of 0.01 to 10 % by weight, of initiators prepared in a polymerization mixture comprising individually or in combination an aliphatic amine monomer of the general formula (A), soluble polymers or copolymers prepared by radical polymerization in the presence of 0.01 to 10% by weight of initiators from monomers of cyclic sterically hindered amines of the general formula (B), soluble polymers prepared by polycondensation of difunctional sterically hindered amines of the general formula (F), soluble polymers or copolymers prepared by polycondensation of difunctional cyclic sterically hindered amines of the general formula (G), soluble copolymers prepared by polycondensation of difunctional cyclic, sterically hindered amines of the general formula (G) and monofunctional cyclic sterically hindered amines in an amount of 0.1 to 15 %. by weight, based on the total polymerization mixture, of the general formula (H), derivatives of sterically hindered cyclic amines of the general formula (O), polymers, copolymers, or natural compounds comprising free reactive groups -OH, -NH2, -COOH, -CHO, oxiranyl, selected from the group poly(vinyl alcohol), cellulose, (2-hydroxyethyl)cellulose, (carboxymethyl)celullose, agar derivatives, polymers obtained by condensation, using alkanediol derivatives, oligomers and polymers of ethylene glycol or propylene glycol, natural or synthetic polymers, comprising a free carboxyl group, amino group or aldehyde group, prepared by additional functionalization of polymers or natural compounds by polymeranalogous reaction with a suitable sterically hindered amine.
POLYMER CARRIER FOR CULTIVATION OF KERATINOCYTES
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AUTHOR(S) : Labsky J., Vacik J., Smetana K., Dvorankova B. (CORPORATE SOURCE Ustav Makromolekularni Chemie Akademie Ved Ceske Republiky; Univerzita Karlova; 1. Lekarska Fakulta Univerzity Karlovy; 3. Lekarska Fakulta Univerzity Karlovy, Czech Rep.).
CHEMICAL ABSTRACTS: 132:32928
SOURCE PCT: Int. Appl. WO 9964563 A1 16 Dec 1999, 30 pp.
DESIGNATED STATES: W: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, DE, DK, EE, ES, FI, GB, GE, GH, GM, HR, HU, ID, IL, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW, AM, AZ, BY, KG, KZ, MD, RU, TJ, TM; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG. (English). (World Intellectual Property Organization).
ABSTRACT: A polymer carrier for keratinocyte cultivation on biologically active polymer bases, prepared by radical polymerization of a polymerization mixture containing 1-95 wt.-% of a radically polymerizable monomer, 0.1-10 wt.-% of a crosslinker, 0.1-10 wt.-% of an initiator, and/or 0.1-60 wt.-% of a solvent, and/or 0.1-60 wt.-% of a polymerizable saccharide derivative, and/or 0.1-50 wt.-% of a polymerizable derivative of a sterically hindered amine, and/or polymerizable derivatives of *-acryloyl- or methacryloyl amino acids and/or their reactive derivatives which can be used for additional modification of polymer carriers with appropriate saccharide or sterically hindered amine derivatives. A hydrophilic polymer carrier with no bonded polymerizable saccharide or sterically hindered amine derivatives can be activated by sorption of specific derivatives of biologically active substances on the carrier surface.
