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2013

Janouskova H, Ray AM, Noulet F, Lelong-Rebel I, Choulier L, Schaffner F, Lehmann M, Martin S, Teisinger J, Dontenwill M.

Activation of p53 pathway by Nutlin-3a inhibits the expression of the therapeutic target α5 integrin in colon cancer cells

Cancer Lett. 2013 Mar 21; doi:pii: S0304-3835(13)00246-2. 10.1016/j.canlet.2013.03.018.

IF = 4.238

Bily J, Grycova L, Holendova B, Jirku M, Janouskova H, Bousova K, Teisinger J.

Characterization of the S100A1 Protein Binding Site on TRPC6 C-Terminus

PLoS One. 2013 May 3;8(5):e62677

IF = 4.092

Boukalova S, Teisinger J, Vlachova V.

Protons stabilize the closed conformation of gain-of-function mutants of the TRPV1 channel

Biochimica Et Biophysica Acta-Molecular Cell Research 2013 Mar;1833(3):520-8

IF = 5.538

Macakova E, Kopecka M, Kukacka Z, Veisova D, Novak P, Man P, Obsil T, Obsilova V

Structural basis of the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1

Biochimica Et Biophysica Acta-General Subjects 2013 May 20; doi:10.1016/j.bbagen.2013.05.025

IF = 5

2012

Rezabkova L, Kacirova M, Sulc M, Herman P, Vecer J, Stepanek M, Obsilova V, Obsil T

Structural modulation of phosducin by the phosphorylation and the 14-3-3 protein binding

Biophysical Journal 2012 Nov;103(9):1960–1969.

IF = 3.653

Grycova L, Holendova B, Bumba L, Bily J, Jirku M, Lansky Z, Teisinger J.

Integrative Binding Sites within Intracellular Termini of TRPV1 Receptor.

PLoS One. 2012;7(10):e48437.

IF = 4.092

Holendova B, Grycova L, Jirku M, Teisinger J.

PtdIns(4,5)P 2 interacts with CaM binding domains on TRPM3 N-terminus

Channels (Austin). 2012 Sep 18;6(6)

IF = 2.14

Krasny L, Pompach P, Strohalm M, Obsilova V, Strnadova M, Novak P and Volny M.

In-situ enrichment of phosphopeptides on MALDI plates modified by ambient ion landing.

J Mass Spectrom. 2012 Oct;47(10):1294–1302

IF = 3.268

Haladova K, Mrazek H, Jecmen T, Halada P, Man P, Novak P, Chmelik J, Obsil T, Sulc M.

The combination of hydrogen/deuterium exchange or chemical cross-linking techniques with mass spectrometry: mapping of human 14-3-3ζ homodimer interface.

J Struct Biol. 2012 Jul;179(1):10-7

IF = 3.406

Janouskova H, Maglott A, Leger DY, Bossert C, Noulet F, Guerin E, Guenot D, Pinel S, Chastagner P, Plenat F, Entz-Werle N, Lehmann-Che J, Godet J, Martin S, Teisinger J, Dontenwill M.

Integrin α5β1 Plays a Critical Role in Resistance to Temozolomide by Interfering with the p53 Pathway in High-Grade Glioma.

Cancer Res. 2012 Jul 15;72(14):3463-70.

IF = 7.856

Holakovska B, Grycova L, Jirku M, Sulc M, Bumba L, Teisinger J.

Calmodulin and S100A1 interact with N-terminus of TRPM3 channel.

J Biol Chem. 2012 May 11;287(20):16645-55.

IF = 5.328

Veisova D, Macakova E, Rezabkova L, Sulc M, Vacha P, Sychrova H, Obsil T, Obsilova V.

Role of individual phosphorylation sites for the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1.

Biochem J. 2012 May 1;443(3):663-70.

IF = 5.016

2011

Rezabkova L, Man P, Novak P, Herman P, Vecer J, Obsilova V, Obsil T.

Structural basis for the 14-3-3 protein-dependent inhibition of the regulator of G-Protein signaling 3 (RGS3) function.

J Biol Chem. 2011 Dec 16;286(50):43527-36.

IF = 5.328

Obsil T, Obsilova V.

Structural basis of 14-3-3 protein functions.

Semin Cell Dev Biol. 2011 Sep;22(7):663-72.

IF = 6.342

Obsil T, Obsilova V.

Structural basis for DNA recognition by FOXO proteins.

Biochim Biophys Acta. 2011 Nov;1813(11):1946-53.

IF = 4.374

Coddou C, Yan Z, Obsil T, Huidobro-Toro JP, Stojilkovic SS.

Activation and regulation of purinergic P2X receptor channels.

Pharmacol Rev. 2011 Sep;63(3):641-83.

IF = 18.861

Valis K, Prochazka L, Boura E, Chladova J, Obsil T, Rohlena J, Truksa J, Dong LF, Ralph SJ, Neuzil J.

Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner.

Cancer Res. 2011 Feb 1;71(3):946-54.

IF = 7.543

Touska F, Marsakova L, Teisinger J, Vlachova V.

A "Cute" Desensitization of TRPV1.

Curr Pharm Biotechnol. 12(1):122-9. Review. 2011

IF = 3.455

Samad A, Sura L, Benedikt J, Ettrich R, Minofar B, Teisinger J, Vlachova V.

The C-terminal basic residues contribute to the chemical and voltage-dependent activation of TRPA1.

Biochem J. 433(1):197-204. 2011

IF = 5.016

Holakovska B, Grycova L, Bily J, Teisinger J.

Characterization of calmodulin binding domains in TRPV2 and TRPV5 C-tails.

Amino Acids 40(2):741-8. 2011

IF = 4.106

2010

Stojilkovic SS, Yan Z, Obsil T, Zemkova H.

Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells.

Cell Mol Neurobiol. 2010 Nov;30(8):1251-8.

IF = 3.226

Veisova, D., Rezabkova, L., Stepanek, M., Novotna, P., Herman, P., Vecer, J., Obsil, T., Obsilova, V.

C-terminal segment of yeast BMH proteins exhibits different structure compared to other 14-3-3 protein isoforms.

Biochemistry 49(18), 3853-3861, 2010

IF = 3.226

Rezabkova, L., Boura, E., Herman, P., Vecer, J., Bourova, L., Sulc, M., Svoboda, P., Obsilova, V., Obsil

14-3-3 protein interacts with and affects the structure of RGS domain of regulator of G-protein signaling 3 (RGS3).

J. Struct. Biol. 170(3), 451-461, 2010

IF = 3.673

Boura E, Rezabkova L, Brynda J, Obsilova V, Obsil T.

Crystal structure of human FOXO4-DBD/DNA complex at 1.9 A resolution reveals new details on FOXO binding to the DNA

Acta Crystallographica Section D, 2010 [Epub ahead of print].

IF = 6.326

Friedlova E, Grycova L, Holakovska B, Silhan J, Janouskova H, Sulc M, Obsilova V, Obsil T, Teisinger J.

The interactions of the C-terminal region of the TRPC6 channel with calmodulin.

Neurochem Int. 2010 Jan;56(2):363-6.

IF = 3.541

Boukalova S, Marsakova L, Teisinger J, Vlachova V.

Conserved residues within the putative S4-S5 region serve distinct functions among thermosensitive TRPV channels.

Physiol Res. 59(6):927-35. 2010

IF = 1.653

2009

Grycova L. - Sklenovsky P. - Lansky Z. - Janovska M. - Otyepka M. - Amler E. - Teisinger J. - Kubala M.

ATP and magnesium drive conformational changes of the Na+/K+-ATPase cytoplasmic headpiece.

Biochimica Et Biophysica Acta-Biomembranes, 1788(5), 1081-1091, 2009

IF = 4.18

Benedikt J. - Samad A. - Ettrich R. - Teisinger J. - Vlachova V.

Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel.

Biochimica Et Biophysica Acta-Molecular Cell Research, 1793(7), 1279-1288, 2009

IF = 4.893

Kubala M. - Grycova L. - Lansky Z. - Sklenovsky P. - Janovska M. - Otyepka M. - Teisinger J.

Changes in electrostatic surface potential of Na+/K+-ATPase cytoplasmic headpiece induced by cytoplasmic ligand(s) binding.

Biophysical Journal, 97(6), 1756-1764, 2009

IF = 4.683

Silhan J. - Vacha P. - Strnadova P. - Vecer J. - Herman P. - Sulc M. - Teisinger J. - Obsilova V. - Obsil T.

14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4.

Journal of Biological Chemistry, 284(29), 19349-19360, 2009

IF = 5.52

Jindrichova M. - Vavra V. - Obsil T. - Stojilkovic S. S. - Zemkova H.

Functional relevance of aromatic residues in the first transmembrane domain of P2X receptors.

Journal of Neurochemistry, 109(3), 923-934, 2009

IF = 4.5

2008

Grycova L. - Lansky Z. - Friedlova E. - Obsilova V. - Janouskova H. - Obsil T. - Teisinger J.

Ionic interactions are essential for TRPV1 C-terminus binding to calmodulin.

Biochemical and Biophysical Research Communications, 375(4), 680-683, 2008

IF = 2.648

Obsilova V. - Nedbalkova E. - Silhan J. - Boura E. - Herman P. - Vecer J. - Sulc M. - Teisinger J. - Dyda F. - Obsil T.

The 14-3-3 protein affects the conformation of the regulatory domain of human tyrosine hydroxylase.

Biochemistry, 47(6), 1768-1777, 2008

IF = 3.379

Mazna P. - Grycova L. - Balik A. - Zemkova H. - Friedlova E. - Obsilova V. - Obsil T. - Teisinger J.

The role of proline residues in the structure and function of human MT2 melatonin receptor

Journal of Pineal Research, 45(4), 361-372, 2008

IF = 5.056

Obsil T. - Obsilova V.

Structure/function relationships underlying regulation of FOXO transcription factors.

Oncogene, 27(16), 2263-2275, 2008

IF = 7.216

Jelinkova I. - Vavra V. - Jindrichova M. - Obsil T. - Zemkova H.W. - Zemkova H. - Stojilkovic S. S.

Identification of P2X(4) receptor transmembrane residues contributing to channel gating and interaction with ivermectin.

Pflügers Archiv, 465(5), 939-950, 2008

IF = 3.526

Obsilova V, Silhan J, Boura E, Teisinger J, Obsil T.

14-3-3 proteins: a family of versatile molecular regulators.

Physiol Res. 57 Suppl 3:S11-21, 2008. Review.

IF = 1.653

Drastichova Z. - Bourova L. - Lisy V. - Hejnova L. - Rudajev V. - Stohr J. - Durchankova D. - Ostasov P. - Teisinger J. - Soukup T. - Novotny J. - Svoboda P.

Subcellular redistribution of trimeric G-proteins--potential mechanism of desensitization of hormone response: internalization, solubilization, down-regulation.

Physiological Research, 57, S1-S10, 2008

IF = 1.653

2007

Grycova L. - Lansky Z. - Friedlova E. - Vlachova V. - Kubala M. - Obsilova V. - Obsil T. - Teisinger J.

ATP binding site on the C-terminus of the vanilloid receptor.

Archives of Biochemistry and Biophysics, 465(2), 389-398, 2007

IF = 2.578

Boura E. - Silhan J. - Herman P. - Vecer J. - Teisinger J. - Obsilova V. - Obsil T.

Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding.

Journal of Biological Chemistry, 282(11), 8265-8275, 2007

IF = 5.581

Benedikt J. - Teisinger J. - Vyklicky ml. L. - Vlachova V.

Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate.

Journal of Neurochemistry, 100(1), 211-224, 2007

IF = 4.451

Zemkova H. - Yan Z. - Liang Z. - Jelinkova I. - Tomic M. - Stojilkovic S. S.

Role of aromatic and charged ectodomain residues in the P2X(4) receptor functions.

Journal of Neurochemistry, 102(4), 1139-1150, 2007

IF = 4.451

Susankova K. - Ettrich R. - Vyklicky st. L. - Teisinger J. - Vlachova V.

Contribution of the putative inner-pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1).

Journal of Neuroscience, 27(28), 7578-7585, 2007

IF = 7.49

Novakova-Tousova K. - Vyklicky st. L. - Susankova K. - Benedikt J. - Samad A. - Teisinger J. - Vlachova V.

Functional changes in the vanilloid receptor subtype 1 channel during and after acute desensitization.

Neuroscience, 149(1), 144-154, 2007

IF = 3.352

2006

Jelinkova I. - Yan Z. - Liang Z. - Moonat S. - Teisinger J. - Stojilkovic S. S. - Zemkova H.

Identification of P2X4 receptor-specific residues contributing to the ivermectin effects on channel deactivation.

Biochemical and Biophysical Research Communications, 349(2), 619-625, 2006

IF = 2.855

Susankova K. - Tousova K. - Vyklicky st. L. - Teisinger J. - Vlachova V.

Reducing and oxidizing agents sensitize heat-activated vanilloid receptor (TRPV1) current.

Molecular Pharmacology, 70(1), 383-394, 2006

IF = 4.469

2005

Mazna P. - Berka K. - Jelinkova I. - Balik A. - Svoboda P. - Obsilova V. - Obsil T. - Teisinger J.

Ligand binding to the human MT2 melatonin receptor: the role of residues in transmembrane domains 3, 6, and 7.

Biochemical and Biophysical Research Communications, 332(3), 726-734, 2005

IF = 3

Obsilova V. - Vecer J. - Herman P. - Pabianova A. - Sulc M. - Teisinger J. - Boura E. - Obsil T.

14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4.

Biochemistry, 44(34), 11608-11617, 2005

IF = 3.848

2004

Lansky Z. - Kubala M. - Ettrich R. - Kuty M. - Plasek J. - Teisinger J. - Schoner W. - Amler E.

The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.

Biochemistry, 43(26), 8303-8311, 2004

IF = 4.008

Obsilova V. - Herman P. - Vecer J. - Sulc M. - Teisinger J. - Obsil T.

14-3-3zeta C-terminal stretch changes its conformation upon ligand binding and phosphorylation at Thr232.

Journal of Biological Chemistry, 279(6), 4531-4540, 2004

IF = 6.355

Silhan J. - Obsilova V. - Vecer J. - Herman P. - Sulc M. - Teisinger J. - Obsil T.

14-3-3 protein C-terminal stretch occupies ligand binding groove and is displaced by phosphopeptide binding.

Journal of Biological Chemistry, 279(47), 49113-49119, 2004

IF = 6.355

Mazna P. - Obsilova V. - Jelinkova I. - Balik A. - Berka K. - Sovova Z. - Ettrich R. - Svoboda P. - Obsil T. - Teisinger J.

Molecular modeling of human MT2 melatonin receptor: the role of Val204, Leu272 and Tyr298 in ligand binding.

Journal of Neurochemistry, 91(4), 836-842, 2004

IF = 4.824

Tousova K. - Susankova K. - Teisinger J. - Vyklicky st. L. - Vlachova V.

Oxidizing reagent copper-o-phenanthroline is an open channel blocker of the vanilloid receptor TRPV1.

Neuropharmacology, 47(2), 273-285, 2004

IF = 3.734

Kubala M. - Obsil T. - Obsilova V. - Lansky Z. - Amler E.

Protein modeling combined with spectroscopic techniques: an attractive quick alternative to obtain structural information.

Physiological Research, 53(Suppl. 1), S187-S197, 2004

IF = 1.14

Svoboda P. - Teisinger J. - Novotny J. - Bourova L. - Drmota T. - Hejnova L. - Moravcova Z. - Lisy V. - Rudajev V. - Stohr J. - Vokurkova A. - Svandova I. - Durchankova D.

Biochemistry of transmembrane signaling mediated by trimeric G proteins.

Physiological Research, 53(Suppl. 1), S141-S152, 2004

IF = 1.14

2003

Krumscheid R. - Susankova K. - Ettrich R. - Teisinger J. - Amler E. - Schoner W.

Localization of catalytic active sites in the large cytoplasmic domain of Na+/K+-ATPase.

Annals of the New York Academy of Sciences, 986(-), 242-244, 2003

IF = 1.892

Hofbauerova K. - Kopecky ml. V. - Ettrich R. - Kubala M. - Teisinger J. - Amler E.

ATP-binding is stabilized by a stacking interaction within the binding site of Na+/K+ -ATPase.

Biochemical and Biophysical Research Communications, 306(2), 416-420, 2003

IF = 2.836

Kubala M. - Teisinger J. - Ettrich R. - Hofbauerova K. - Kopecky ml. V. - Baumruk V. - Krumscheid R. - Plasek J. - Schoner W. - Amler E.

Eight amino acids form the ATP recognition site of Na(+)/K(+)-ATPase.

Biochemistry, 42(21), 6446-6452, 2003

IF = 3.922

Vlachova V. - Teisinger J. - Susankova K. - Lyfenko A. - Ettrich R. - Vyklicky st. L.

Functional role of C-terminal cytoplasmic tail of rat vanilloid receptor 1.

Journal of Neuroscience, 23(4), 1340-1350, 2003

IF = 8.306

2002

Kubala M. - Hofbauerova K. - Ettrich R. - Kopecky ml. V. - Krumscheid R. - Plasek J. - Teisinger J. - Schoner W. - Amler E.

Phe(475) and Glu(446) but not Ser(445) participate in ATP-binding to the alpha-subunit of Na(+)/K(+)-ATPase.

Biochemical and Biophysical Research Communications, 297(1), 154-159, 2002

IF = 2.935

Abdrachmanova G. - Teisinger J. - Vyklicky ml. L.

Molecular and functional properties of synaptically activated NMDA receptors in neonatal motoneurons in rat spinal cord slices.

Journal of Physiology, 538(1), 53-63, 2002

IF = 4.65

Vyklicky st. L. - Lyfenko A. - Susankova K. - Teisinger J. - Vlachova V.

Reducing agent dithiothreitol facilitates activity of the capsaicin receptor VR-1.

Neuroscience, 111(3), 435-441, 2002

IF = 3.457