Structural Biology of Signaling Proteins - Institute of Physiology AS CR, v.v.i.

Structural Biology
of Signaling Proteins

We obtained the prize for the best publication of Institute of Physiology for 2017

Our new paper in FEBS Journal: September 2018

14-3-3 protein masks the nuclear localization sequence of caspase-2.

Our two new papers in BBA-General Subjects: July and August 2018

CaMKK2 kinase domain interacts with the autoinhibitory region through the N-terminal lobe including the RP insert.

14-3-3 protein directly interacts with the kinase domain of calcium/calmodulin-dependent protein kinase kinase (CaMKK2).

Succesfull defences June + September 2018:

Bachelor thesis: Klára Kohoutová and Martina Mikulů

Ph.D. thesis: Olívia Petrvalská and Salome Kylarová

Our new paper in BBRC: November 2017

Human procaspase-2 phosphorylation at both S139 and S164 is required for 14-3-3 binding.

Our new paper in PNAS: November 2017

Molecular basis of the 14-3-3 protein-dependent activation of yeast neutral trehalase Nth1.

May 2017 .... we moved to BIOCEV....

Our new paper in Biophysical Journal: April 2017

Structural Basis for the 14-3-3 Protein-Dependent Inhibition of Phosducin Function.