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Výzkumné centrum Nová antivirotika a antineoplastika
Financováno Ministerstvem Školství České Republiky
Výzkumné centrum Nová antivirotika a antineoplastika
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Publikace Seznam publikací za rok 2006

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46. Németh-Pongrácz, V.; Snášel, J.; Rumlová, M.; Pichová, I.; Vértessy, B. G.: "Interacting partners of M-PMV nucleocapsid-dUTPase" Nucleos. Nucleot. Nucl. 2006, 25, 1197-1200.
45. Sobociková, M.; Štěpnička, P.; Ramella, D.; Kotora, M.: "Synthesis of 1-alkanoyl-1'-(trifluoroacetyl)ferrocenes" Collect. Czech. Chem. Commun. 2006, 71, 190-196.
44. Nečas, D.; Turský, M.; Tišlerová, I.; Kotora, M.: "Nickel-catalyzed cyclization of α,ω-dienes: formation vs. cleavage of C–C bonds" New J. Chem. 2006, 30, 671-674.
43. Turský, M.; Nečas, D.; Drabina, P.; Sedlák, M.; Kotora, M.: "Rhodium-Catalyzed Deallylation of Allylmalonates and Related Compounds" Organometallics 2006, 25, 901-907.
42. Herrmann, P.; Kotora, M.; Buděšínský, M.; Šaman, D.; Císařová, I.: "Synthesis of (±)-3-Methoxyestra-1,3,5(10)-trienes by the Repetitive Use of Negishi Reagent" Org. Lett. 2006, 8, 1315-1318.
41. Holý, A.: "Antiviral acyclic nucleoside phosphonates structure activity studies" Antivirals Res. 2006, 71, 248-253.
40. Česnek, M.; Masojídková, M.; Holý, A.; Šolínová, V.; Koval, D; Kašička, V.: "Synthesis and properties of 2-guanidinopurines" Collect. Czech. Chem. Commun. 2006, 71, 1303-1319.
39. Potměšil, P.; Krečmerová, M.; Kmoníčková, E.; Holý, A.; Zídek, Z.: "Nucleotide analogues with immunobiological properties: 9-[2-Hydroxy-3-(phosphonomethoxy)propyl]-adenine (HPMPA), -2,6-diaminopurine (HPMPDAP), and their N6-substituted derivatives" Eur. J. Pharmacol. 2006, 540, 191-199.
38. Hořejší, K.; Andrei, G.; De Clerq, E.; Snoeck, R.; Pohl, R; Holý, A.: "Tricyclic etheno analogs of PMEG and PMEDAP: Synthesis and biological activity" Bioorg. Med. Chem. 2006, 14, 8057-8065.
37. Šolínová, V.; Kašička, V.; Koval, D.; Česnek, M.; Holý, A.: "Determination of acid–base dissociation constants of amino- and guanidinopurine nucleotide analogs and related compounds by capillary zone electrophoresis" Electrophoresis 2006, 27, 1006-1019.
36. Hocek, M.; Šilhár, P.; Pohl, R.: "Cytostatic and activiral 6-arylpurine ribonucleosides VIII. Synthesis and evaluation of 6-substituted purine 3'-deoxyribonucletides" Collect. Czech. Chem. Commun. 2006, 71, 1484-1496.
35. Turek, P.; Novák, P.; Pohl, R.; Hocek, M.; Kotora, M.: "Preparation of Highly Substituted 6-Arylpurine Ribonucleosides by Ni-Catalyzed Cyclotrimerization. Scope of the Reaction" J. Org. Chem. 2006, 71, 8978-8981.
34. Klimentová, J.; Kosák, P.; Vávrová, K.; Holas, T.; Hrabálek, A.: "Influence of terminal branching on the transdermal permeation-enhancing activity in fatty alcohols and acids" Bioorg. Med. Chem. 2006, 14(23), 7681-7687.
33. Holas, T.; Vávrová, K.; Šíma, M.; Klimentová, J.; Hrabálek, A.: "Synthesis and transdermal permeation-enhancing activity of carbonate and carbamate analogs of Transkarbam 12" Bioorg. Med. Chem. 2006, 14(23), 7671-7680.
32. Kuchař, M.; Pohl, R.; Votruba, I.; Hocek, M.: "Synthesis of Purines Bearing Functionalized C-Substituents by the Conjugate Addition of Nucleophiles to 6-Vinylpurines and 6-Ethynylpurines" Eur. J. Org. Chem. 2006, 5083-5098.
31. Liebl, D.; Difato, F.; Horníková, L.; Mannová, P.; Štokrová, J.; Forstová, J: "Mouse Polyomavirus Enters Early Endosomes, Requires Their Acidic pH for Productive Infection, and Meets Transferrin Cargo in Rab11-Positive Endosomes" J. Virol. 2006, 80, 4610-4622.
30. Hřebabecký, H.; Masojídková, M.; Dračínský, M.; Holý, A.: "Synthesis of Novel Conformationally Locked Carbocyclic Nucleosides Derived from 3-(Hydroxymethyl)bicyclo[2.2.1]heptane-2,5-diol" Collect. Czech. Chem. Commun. 2006, 71, 871-888.
29. Šála, M.; Hřebabecký, H.; Masojídková, M.; Holý, A.: "Synthesis of Novel Racemic Conformationally Locked Carbocyclic Nucleosides Derived from 7-Substituted Bicyclo{2.2.1]hept-5-ene-2,2-dimethanols" Collect. Czech. Chem. Commun. 2006, 71, 635-649.
28. Hocek, M.; Šilhár, P.; Shih, I.; Mabery, E.; Mackman, R.: "Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: Synthesis and evaluation of 6-substituted purine L-ribonucleosides" Bioorg. Med. Chem. Lett. 2006, 16, 5290?5293.
27. Hrabálek, A.; Doležal, P.; Vávrová, K.; Zbytovská, J.; Holas, T.; Klimentová, J.; Novotný, J.: "Synthesis and Enhancing Effect of Transkarbam 12 on the Transdermal Delivery of Theophylline, Clotrimazole, Flobufen, and Griseofulvin" Pharm. Res. 2006, 5, 912-919.
26. Čapek, P.; Pohl, R.; Hocek, M.: "Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl)- and (purin-6-yl)phenylalanines." Org. Biomol. Chem. 2006, 4, 2278-2284.
25. Šilhár, P.; Pohl, R.; Votruba, I.; Klepetářová, B.; Hocek, M.: "Synthesis of 6-Amino-, 6-Methyl- and 6-Aryl- 2-(Hydroxymethyl)purine Bases and Nucleosides" Collect. Czech. Chem. Commun. 2006, 71, 788-803.
24. Šilhár, P.; Pohl, R.; Votruba, I.; Hocek, M.: "Synthesis and Cytostatic Activity of Novel 6-(Difluoromethyl)purine Bases and Nucleosides" Synthesis 2006, 1848-1852.
23. Krečmerová, M.; Masojídková, M.; Holý, A.: "Preparation of C-5 Substituted Cidofovir Derivatives" Collect. Czech. Chem. Commun. 2006, 71, 579-594.
22. Vrbovská, S.; Holý, A.; Pohl, R.; Masojídková, M.: "Bifunctional Acyclic Nucleoside Phosphonates. 1. Symmetrical 1,3-Bis[(phosphonomethoxy)propan-2-yl] Derivatives of Purines and Pyrimidines" Collect. Czech. Chem. Commun. 2006, 71, 543-566.
21. Novák, P.; Pohl, R.; Kotora, M.; Hocek, M.: "Synthesis of C-Aryldeoxyribosides by [2 + 2 + 2]-Cyclotrimerization Catalyzed by Rh, Ni, Co, and Ru Complexes" Org. Lett. 2006, 8, 2051-2054.
20. Majerová-Uhlíková, T.; Dantuma, N. P.; Lindsten, K.; Masucci, M. G.; Konvalinka, J.: "Non-infectious Fluorimetric Assay for Phenotyping of Drug-Resistant HIV Proteinase Mutants" J. Clin. Virol. 2006, 36, 50-59.
19. Vale-Silva, L. A.; Buchta, V.; Vokurková, D.; Pour, M.: "Investigation of the mechanism of action of 3-(4-bromophenyl)-5-acyloxymethyl-2,5-dihydrofuran-2-one against Candida albicans by flow citometry" Bioorg. Med. Chem. Lett. 2006, 16, 2492-2495.
18. Matějíček, P., Cígler, P., Procházka, K., and Král, V.: "Molecular Assembly of Metallacarboranes in Water: Light Scattering and Microscopy Study" Langmuir 2006, 22, 575-581.
17. Mesters, J. R.; Bařinka, C.; Li, W., Tsukamoto, T.; Majer, P.; Slusher, B.; Konvalinka, J.; Hilgenfeld, R.: "Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer" EMBO J. 2006, 25, 1375-1384.
16. Hořejší, K.; Pohl, R.; Holý, A.: "Tricyclic purine analogs derived from 2-amino-6-chloropurine and 2,6-diaminopurine and their methylated quarternary salts" Collect. Czech. Chem. Commun. 2006, 71, 77-90.